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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SDR42E1
Full Name:
Short-chain dehydrogenase/reductase family 42E member 1
Alias:
Type:
Mass (Da):
44284
Number AA:
393
UniProt ID:
Q8WUS8
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
D
P
K
R
S
Q
K
E
S
V
L
I
Site 2
S10
P
K
R
S
Q
K
E
S
V
L
I
T
G
G
S
Site 3
T14
Q
K
E
S
V
L
I
T
G
G
S
G
Y
F
G
Site 4
T46
D
I
S
S
P
A
Q
T
I
P
E
G
I
K
F
Site 5
S62
Q
G
D
I
R
H
L
S
D
V
E
K
A
F
Q
Site 6
S85
H
I
A
S
Y
G
M
S
G
R
E
Q
L
N
R
Site 7
T103
K
E
V
N
V
R
G
T
D
N
I
L
Q
V
C
Site 8
S139
V
I
R
N
G
D
E
S
L
P
Y
L
P
L
H
Site 9
Y142
N
G
D
E
S
L
P
Y
L
P
L
H
L
H
P
Site 10
Y152
L
H
L
H
P
D
H
Y
S
R
T
K
S
I
A
Site 11
S153
H
L
H
P
D
H
Y
S
R
T
K
S
I
A
E
Site 12
S157
D
H
Y
S
R
T
K
S
I
A
E
Q
K
V
L
Site 13
T169
K
V
L
E
A
N
A
T
P
L
D
R
G
D
G
Site 14
T180
R
G
D
G
V
L
R
T
C
A
L
R
P
A
G
Site 15
Y189
A
L
R
P
A
G
I
Y
G
P
G
E
Q
R
H
Site 16
S202
R
H
L
P
R
I
V
S
Y
I
E
K
G
L
F
Site 17
Y203
H
L
P
R
I
V
S
Y
I
E
K
G
L
F
K
Site 18
Y213
K
G
L
F
K
F
V
Y
G
D
P
R
S
L
V
Site 19
S248
A
D
K
G
H
I
A
S
G
Q
P
Y
F
I
S
Site 20
Y252
H
I
A
S
G
Q
P
Y
F
I
S
D
G
R
P
Site 21
S255
S
G
Q
P
Y
F
I
S
D
G
R
P
V
N
N
Site 22
T319
T
R
T
E
V
Y
K
T
G
V
T
H
Y
F
S
Site 23
T322
E
V
Y
K
T
G
V
T
H
Y
F
S
L
E
K
Site 24
Y324
Y
K
T
G
V
T
H
Y
F
S
L
E
K
A
K
Site 25
S326
T
G
V
T
H
Y
F
S
L
E
K
A
K
K
E
Site 26
S359
A
H
G
H
G
R
S
S
G
S
R
D
S
E
C
Site 27
S361
G
H
G
R
S
S
G
S
R
D
S
E
C
F
V
Site 28
S364
R
S
S
G
S
R
D
S
E
C
F
V
W
D
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation