KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
RNF138
Full Name:
E3 ubiquitin-protein ligase RNF138
Alias:
HSD-4; ring finger protein 138; RN138; STRIN
Type:
Ubiquitin ligase; Ubiquitin conjugating system; Ligase; EC 6.3.2.-
Mass (Da):
28193
Number AA:
245
UniProt ID:
Q8WVD3
International Prot ID:
IPI00328938
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005622
Uniprot
OncoNet
Molecular Function:
GO:0016874
GO:0019901
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0016055
GO:0019941
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
A
E
D
L
S
A
A
T
S
Y
T
E
Site 2
S10
E
D
L
S
A
A
T
S
Y
T
E
D
D
F
Y
Site 3
Y17
S
Y
T
E
D
D
F
Y
C
P
V
C
Q
E
V
Site 4
Y96
C
A
K
Q
I
K
F
Y
R
M
R
H
H
Y
K
Site 5
Y108
H
Y
K
S
C
K
K
Y
Q
D
E
Y
G
V
S
Site 6
Y112
C
K
K
Y
Q
D
E
Y
G
V
S
S
I
I
P
Site 7
S124
I
I
P
N
F
Q
I
S
Q
D
S
V
G
N
S
Site 8
S127
N
F
Q
I
S
Q
D
S
V
G
N
S
N
R
S
Site 9
S131
S
Q
D
S
V
G
N
S
N
R
S
E
T
S
T
Site 10
S134
S
V
G
N
S
N
R
S
E
T
S
T
S
D
N
Site 11
T136
G
N
S
N
R
S
E
T
S
T
S
D
N
T
E
Site 12
T138
S
N
R
S
E
T
S
T
S
D
N
T
E
T
Y
Site 13
S139
N
R
S
E
T
S
T
S
D
N
T
E
T
Y
Q
Site 14
T144
S
T
S
D
N
T
E
T
Y
Q
E
N
T
S
S
Site 15
Y145
T
S
D
N
T
E
T
Y
Q
E
N
T
S
S
S
Site 16
S151
T
Y
Q
E
N
T
S
S
S
G
H
P
T
F
K
Site 17
S152
Y
Q
E
N
T
S
S
S
G
H
P
T
F
K
C
Site 18
T156
T
S
S
S
G
H
P
T
F
K
C
P
L
C
Q
Site 19
T168
L
C
Q
E
S
N
F
T
R
Q
R
L
L
D
H
Site 20
S201
S
L
P
W
G
D
P
S
Q
I
T
R
N
F
V
Site 21
Y219
N
Q
R
H
Q
F
D
Y
G
E
F
V
N
L
Q
Site 22
Y233
Q
L
D
E
E
T
Q
Y
Q
T
A
V
E
E
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation