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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TWIST2
Full Name:
Twist-related protein 2
Alias:
Bhlha39; Dermo1; Twist 2; Twist2
Type:
Mass (Da):
18124
Number AA:
160
UniProt ID:
Q8WVJ9
International Prot ID:
IPI00103145
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0016564
PhosphoSite+
KinaseNET
Biological Process:
GO:0030154
GO:0007275
GO:0045668
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S5
_
_
_
M
E
E
G
S
S
S
P
V
S
P
V
Site 2
S6
_
_
M
E
E
G
S
S
S
P
V
S
P
V
D
Site 3
S7
_
M
E
E
G
S
S
S
P
V
S
P
V
D
S
Site 4
S10
E
G
S
S
S
P
V
S
P
V
D
S
L
G
T
Site 5
S14
S
P
V
S
P
V
D
S
L
G
T
S
E
E
E
Site 6
S18
P
V
D
S
L
G
T
S
E
E
E
L
E
R
Q
Site 7
Y35
R
F
G
R
K
R
R
Y
S
K
K
S
S
E
D
Site 8
S36
F
G
R
K
R
R
Y
S
K
K
S
S
E
D
G
Site 9
S39
K
R
R
Y
S
K
K
S
S
E
D
G
S
P
T
Site 10
S40
R
R
Y
S
K
K
S
S
E
D
G
S
P
T
P
Site 11
S44
K
K
S
S
E
D
G
S
P
T
P
G
K
R
G
Site 12
T46
S
S
E
D
G
S
P
T
P
G
K
R
G
K
K
Site 13
S55
G
K
R
G
K
K
G
S
P
S
A
Q
S
F
E
Site 14
S57
R
G
K
K
G
S
P
S
A
Q
S
F
E
E
L
Site 15
S60
K
G
S
P
S
A
Q
S
F
E
E
L
Q
S
Q
Site 16
S66
Q
S
F
E
E
L
Q
S
Q
R
I
L
A
N
V
Site 17
T79
N
V
R
E
R
Q
R
T
Q
S
L
N
E
A
F
Site 18
S81
R
E
R
Q
R
T
Q
S
L
N
E
A
F
A
A
Site 19
T95
A
L
R
K
I
I
P
T
L
P
S
D
K
L
S
Site 20
S98
K
I
I
P
T
L
P
S
D
K
L
S
K
I
Q
Site 21
S102
T
L
P
S
D
K
L
S
K
I
Q
T
L
K
L
Site 22
T106
D
K
L
S
K
I
Q
T
L
K
L
A
A
R
Y
Site 23
Y118
A
R
Y
I
D
F
L
Y
Q
V
L
Q
S
D
E
Site 24
Y135
N
K
M
T
S
C
S
Y
V
A
H
E
R
L
S
Site 25
Y143
V
A
H
E
R
L
S
Y
A
F
S
V
W
R
M
Site 26
S146
E
R
L
S
Y
A
F
S
V
W
R
M
E
G
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation