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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
UBE2Q2
Full Name:
Ubiquitin-conjugating enzyme E2 Q2
Alias:
DKFZp762C143; EC 6.3.2.19; UB2Q2; Ubiquitin carrier protein Q2; Ubiquitin-conjugating enzyme E2Q family member 2; Ubiquitin-protein ligase Q2
Type:
Ubiquitin ligase; Ubiquitin conjugating system; Ligase; EC 6.3.2.19
Mass (Da):
42818
Number AA:
375
UniProt ID:
Q8WVN8
International Prot ID:
IPI00103165
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0004842
PhosphoSite+
KinaseNET
Biological Process:
GO:0019941
GO:0043687
GO:0051246
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S15
A
E
L
K
F
L
A
S
I
F
D
K
N
H
E
Site 2
S28
H
E
R
F
R
I
V
S
W
K
L
D
E
L
H
Site 3
S45
F
L
V
P
Q
Q
G
S
P
H
S
L
P
P
P
Site 4
S48
P
Q
Q
G
S
P
H
S
L
P
P
P
L
T
L
Site 5
T54
H
S
L
P
P
P
L
T
L
H
C
N
I
T
E
Site 6
T60
L
T
L
H
C
N
I
T
E
S
Y
P
S
S
S
Site 7
S62
L
H
C
N
I
T
E
S
Y
P
S
S
S
P
I
Site 8
Y63
H
C
N
I
T
E
S
Y
P
S
S
S
P
I
W
Site 9
S65
N
I
T
E
S
Y
P
S
S
S
P
I
W
F
V
Site 10
S66
I
T
E
S
Y
P
S
S
S
P
I
W
F
V
D
Site 11
S67
T
E
S
Y
P
S
S
S
P
I
W
F
V
D
S
Site 12
S74
S
P
I
W
F
V
D
S
E
D
P
N
L
T
S
Site 13
S81
S
E
D
P
N
L
T
S
V
L
E
R
L
E
D
Site 14
S138
G
T
T
E
E
V
T
S
E
E
E
E
E
E
E
Site 15
Y157
D
I
E
D
L
D
H
Y
E
M
K
E
E
E
P
Site 16
S166
M
K
E
E
E
P
I
S
G
K
K
S
E
D
E
Site 17
S170
E
P
I
S
G
K
K
S
E
D
E
G
I
E
K
Site 18
T189
I
L
E
K
I
R
K
T
Q
R
Q
D
H
L
N
Site 19
S200
D
H
L
N
G
A
V
S
G
S
V
Q
A
S
D
Site 20
S202
L
N
G
A
V
S
G
S
V
Q
A
S
D
R
L
Site 21
S206
V
S
G
S
V
Q
A
S
D
R
L
M
K
E
L
Site 22
Y217
M
K
E
L
R
D
I
Y
R
S
Q
S
Y
K
T
Site 23
S219
E
L
R
D
I
Y
R
S
Q
S
Y
K
T
G
I
Site 24
S221
R
D
I
Y
R
S
Q
S
Y
K
T
G
I
Y
S
Site 25
S228
S
Y
K
T
G
I
Y
S
V
E
L
I
N
D
S
Site 26
S235
S
V
E
L
I
N
D
S
L
Y
D
W
H
V
K
Site 27
Y237
E
L
I
N
D
S
L
Y
D
W
H
V
K
L
Q
Site 28
S250
L
Q
K
V
D
P
D
S
P
L
H
S
D
L
Q
Site 29
S254
D
P
D
S
P
L
H
S
D
L
Q
I
L
K
E
Site 30
Y267
K
E
K
E
G
I
E
Y
I
L
L
N
F
S
F
Site 31
S314
L
L
T
K
Q
G
W
S
S
A
Y
S
I
E
S
Site 32
S315
L
T
K
Q
G
W
S
S
A
Y
S
I
E
S
V
Site 33
S318
Q
G
W
S
S
A
Y
S
I
E
S
V
I
M
Q
Site 34
Y346
F
G
A
N
K
N
Q
Y
N
L
A
R
A
Q
Q
Site 35
Y355
L
A
R
A
Q
Q
S
Y
N
S
I
V
Q
I
H
Site 36
Y368
I
H
E
K
N
G
W
Y
T
P
P
K
E
D
G
Site 37
T369
H
E
K
N
G
W
Y
T
P
P
K
E
D
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation