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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
WDR60
Full Name:
WD repeat-containing protein 60
Alias:
FLJ10300; WD repeat domain 60
Type:
Mass (Da):
122640
Number AA:
UniProt ID:
Q8WVS4
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T8
M
E
P
G
K
R
R
T
K
D
D
T
W
K
A
Site 2
T12
K
R
R
T
K
D
D
T
W
K
A
D
D
L
R
Site 3
S27
K
H
L
W
A
I
Q
S
G
G
S
K
E
E
R
Site 4
S45
E
K
K
L
R
K
E
S
E
M
D
L
P
E
H
Site 5
S66
D
P
D
Q
D
A
R
S
R
D
R
V
A
E
V
Site 6
S79
E
V
H
T
A
K
E
S
P
R
G
E
R
D
R
Site 7
S114
K
H
R
E
A
E
K
S
H
S
R
G
K
D
R
Site 8
T137
R
K
E
E
L
R
Q
T
V
A
H
H
N
L
L
Site 9
S163
R
A
E
R
K
G
R
S
V
S
K
V
R
S
E
Site 10
S165
E
R
K
G
R
S
V
S
K
V
R
S
E
E
K
Site 11
S169
R
S
V
S
K
V
R
S
E
E
K
D
E
D
S
Site 12
S176
S
E
E
K
D
E
D
S
E
R
G
D
E
D
R
Site 13
Y187
D
E
D
R
E
R
R
Y
R
E
R
K
L
Q
Y
Site 14
S197
R
K
L
Q
Y
G
D
S
K
D
N
P
L
K
Y
Site 15
Y204
S
K
D
N
P
L
K
Y
W
L
Y
K
E
E
G
Site 16
Y207
N
P
L
K
Y
W
L
Y
K
E
E
G
E
R
R
Site 17
S231
D
K
K
H
R
E
K
S
S
T
R
E
K
R
E
Site 18
S232
K
K
H
R
E
K
S
S
T
R
E
K
R
E
K
Site 19
T233
K
H
R
E
K
S
S
T
R
E
K
R
E
K
Y
Site 20
Y240
T
R
E
K
R
E
K
Y
S
K
E
K
S
N
S
Site 21
S241
R
E
K
R
E
K
Y
S
K
E
K
S
N
S
F
Site 22
S245
E
K
Y
S
K
E
K
S
N
S
F
S
D
K
G
Site 23
S247
Y
S
K
E
K
S
N
S
F
S
D
K
G
E
E
Site 24
S249
K
E
K
S
N
S
F
S
D
K
G
E
E
R
H
Site 25
S274
F
D
D
E
R
H
Q
S
N
V
D
R
K
E
K
Site 26
S282
N
V
D
R
K
E
K
S
A
K
D
E
P
R
K
Site 27
S303
E
H
R
N
R
G
A
S
S
K
R
D
G
T
S
Site 28
S304
H
R
N
R
G
A
S
S
K
R
D
G
T
S
S
Site 29
T309
A
S
S
K
R
D
G
T
S
S
Q
H
A
E
N
Site 30
S311
S
K
R
D
G
T
S
S
Q
H
A
E
N
L
V
Site 31
S327
N
H
G
K
D
K
D
S
R
R
K
H
G
H
E
Site 32
T352
Q
R
P
G
G
E
E
T
V
E
I
E
K
E
E
Site 33
T360
V
E
I
E
K
E
E
T
D
L
E
N
A
R
A
Site 34
Y370
E
N
A
R
A
D
A
Y
T
A
S
C
E
D
D
Site 35
T371
N
A
R
A
D
A
Y
T
A
S
C
E
D
D
F
Site 36
S373
R
A
D
A
Y
T
A
S
C
E
D
D
F
E
D
Site 37
Y381
C
E
D
D
F
E
D
Y
E
D
D
F
E
V
C
Site 38
S395
C
D
G
D
D
D
E
S
S
N
E
P
E
S
R
Site 39
S396
D
G
D
D
D
E
S
S
N
E
P
E
S
R
E
Site 40
S401
E
S
S
N
E
P
E
S
R
E
K
L
E
E
L
Site 41
S434
N
E
R
I
G
E
L
S
L
K
L
F
Q
K
R
Site 42
T444
L
F
Q
K
R
G
R
T
E
F
E
K
E
P
R
Site 43
T452
E
F
E
K
E
P
R
T
D
T
N
S
S
P
S
Site 44
T454
E
K
E
P
R
T
D
T
N
S
S
P
S
R
A
Site 45
S456
E
P
R
T
D
T
N
S
S
P
S
R
A
S
V
Site 46
S457
P
R
T
D
T
N
S
S
P
S
R
A
S
V
C
Site 47
S462
N
S
S
P
S
R
A
S
V
C
G
I
F
V
D
Site 48
S472
G
I
F
V
D
F
A
S
A
S
H
R
Q
K
S
Site 49
S474
F
V
D
F
A
S
A
S
H
R
Q
K
S
R
T
Site 50
S479
S
A
S
H
R
Q
K
S
R
T
Q
A
L
K
Q
Site 51
T481
S
H
R
Q
K
S
R
T
Q
A
L
K
Q
K
M
Site 52
T491
L
K
Q
K
M
R
S
T
K
L
L
R
L
I
D
Site 53
Y519
P
V
N
E
Y
D
M
Y
I
R
N
F
G
K
K
Site 54
Y532
K
K
N
T
K
Q
A
Y
V
Q
C
N
E
D
N
Site 55
T551
I
Q
T
E
E
I
E
T
R
E
V
W
T
Q
H
Site 56
T556
I
E
T
R
E
V
W
T
Q
H
P
G
E
S
T
Site 57
S562
W
T
Q
H
P
G
E
S
T
V
V
S
G
G
S
Site 58
T563
T
Q
H
P
G
E
S
T
V
V
S
G
G
S
E
Site 59
S566
P
G
E
S
T
V
V
S
G
G
S
E
Q
R
D
Site 60
T574
G
G
S
E
Q
R
D
T
S
D
A
V
V
M
P
Site 61
S575
G
S
E
Q
R
D
T
S
D
A
V
V
M
P
K
Site 62
S613
D
R
L
A
A
E
P
S
W
N
L
R
A
Q
D
Site 63
Y624
R
A
Q
D
R
A
L
Y
F
S
D
S
S
S
Q
Site 64
S626
Q
D
R
A
L
Y
F
S
D
S
S
S
Q
L
N
Site 65
S628
R
A
L
Y
F
S
D
S
S
S
Q
L
N
T
S
Site 66
S630
L
Y
F
S
D
S
S
S
Q
L
N
T
S
L
P
Site 67
T634
D
S
S
S
Q
L
N
T
S
L
P
F
L
Q
N
Site 68
S635
S
S
S
Q
L
N
T
S
L
P
F
L
Q
N
R
Site 69
S645
F
L
Q
N
R
K
V
S
S
L
H
T
S
R
V
Site 70
S646
L
Q
N
R
K
V
S
S
L
H
T
S
R
V
Q
Site 71
T649
R
K
V
S
S
L
H
T
S
R
V
Q
R
Q
M
Site 72
S650
K
V
S
S
L
H
T
S
R
V
Q
R
Q
M
V
Site 73
S659
V
Q
R
Q
M
V
V
S
V
H
D
L
P
E
K
Site 74
S667
V
H
D
L
P
E
K
S
F
V
P
L
L
D
S
Site 75
S730
V
W
D
L
R
E
D
S
R
L
H
Y
S
V
T
Site 76
Y734
R
E
D
S
R
L
H
Y
S
V
T
L
S
D
G
Site 77
S735
E
D
S
R
L
H
Y
S
V
T
L
S
D
G
F
Site 78
T737
S
R
L
H
Y
S
V
T
L
S
D
G
F
W
T
Site 79
T744
T
L
S
D
G
F
W
T
F
R
T
A
T
F
S
Site 80
T747
D
G
F
W
T
F
R
T
A
T
F
S
T
D
G
Site 81
S758
S
T
D
G
I
L
T
S
V
N
H
R
S
P
L
Site 82
S763
L
T
S
V
N
H
R
S
P
L
Q
A
V
E
P
Site 83
S772
L
Q
A
V
E
P
I
S
T
S
V
H
K
K
Q
Site 84
S774
A
V
E
P
I
S
T
S
V
H
K
K
Q
S
F
Site 85
S780
T
S
V
H
K
K
Q
S
F
V
L
S
P
F
S
Site 86
S784
K
K
Q
S
F
V
L
S
P
F
S
T
Q
E
E
Site 87
S787
S
F
V
L
S
P
F
S
T
Q
E
E
M
S
G
Site 88
S796
Q
E
E
M
S
G
L
S
F
H
I
A
S
L
D
Site 89
S849
A
L
I
Q
L
G
D
S
L
S
H
K
G
N
E
Site 90
S851
I
Q
L
G
D
S
L
S
H
K
G
N
E
F
W
Site 91
T860
K
G
N
E
F
W
G
T
T
Q
T
L
N
V
K
Site 92
T863
E
F
W
G
T
T
Q
T
L
N
V
K
F
L
P
Site 93
S933
L
A
G
C
S
D
G
S
I
R
L
H
Q
L
S
Site 94
S950
F
P
L
L
Q
W
D
S
S
T
D
S
H
A
V
Site 95
S951
P
L
L
Q
W
D
S
S
T
D
S
H
A
V
T
Site 96
T952
L
L
Q
W
D
S
S
T
D
S
H
A
V
T
G
Site 97
S954
Q
W
D
S
S
T
D
S
H
A
V
T
G
L
Q
Site 98
T958
S
T
D
S
H
A
V
T
G
L
Q
W
S
P
T
Site 99
Y980
Q
D
D
T
S
N
I
Y
I
W
D
L
L
Q
S
Site 100
S998
P
V
A
K
Q
Q
V
S
P
N
R
L
V
A
M
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation