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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KBTBD7
Full Name:
Kelch repeat and BTB domain-containing protein 7
Alias:
Type:
Mass (Da):
77163
Number AA:
684
UniProt ID:
Q8WVZ9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S3
_
_
_
_
_
M
Q
S
R
E
D
V
P
R
S
Site 2
S10
S
R
E
D
V
P
R
S
R
R
L
A
S
P
R
Site 3
S15
P
R
S
R
R
L
A
S
P
R
G
G
R
R
P
Site 4
S26
G
R
R
P
K
R
I
S
K
P
S
V
S
A
F
Site 5
S29
P
K
R
I
S
K
P
S
V
S
A
F
F
T
G
Site 6
S31
R
I
S
K
P
S
V
S
A
F
F
T
G
P
E
Site 7
T35
P
S
V
S
A
F
F
T
G
P
E
E
L
K
D
Site 8
T43
G
P
E
E
L
K
D
T
A
H
S
A
A
L
L
Site 9
T78
T
P
G
S
G
P
G
T
G
R
L
F
S
C
N
Site 10
S83
P
G
T
G
R
L
F
S
C
N
R
N
V
L
A
Site 11
Y105
S
M
F
T
G
G
M
Y
E
S
Q
Q
A
S
V
Site 12
S107
F
T
G
G
M
Y
E
S
Q
Q
A
S
V
T
M
Site 13
S121
M
H
D
V
D
A
E
S
F
E
V
L
V
D
Y
Site 14
S135
Y
C
Y
T
G
R
V
S
L
S
E
A
N
V
Q
Site 15
S137
Y
T
G
R
V
S
L
S
E
A
N
V
Q
R
L
Site 16
Y145
E
A
N
V
Q
R
L
Y
A
A
S
D
M
L
Q
Site 17
S148
V
Q
R
L
Y
A
A
S
D
M
L
Q
L
E
Y
Site 18
Y155
S
D
M
L
Q
L
E
Y
V
R
E
A
C
A
S
Site 19
S162
Y
V
R
E
A
C
A
S
F
L
A
R
R
L
D
Site 20
S190
F
D
H
H
K
L
R
S
Q
A
Q
S
Y
I
A
Site 21
S194
K
L
R
S
Q
A
Q
S
Y
I
A
H
N
F
K
Site 22
S204
A
H
N
F
K
Q
L
S
R
M
G
S
I
R
E
Site 23
S208
K
Q
L
S
R
M
G
S
I
R
E
E
T
L
A
Site 24
S230
L
A
V
L
R
L
D
S
L
D
I
E
S
E
R
Site 25
S235
L
D
S
L
D
I
E
S
E
R
T
V
C
H
V
Site 26
S257
A
A
K
E
R
G
P
S
A
A
E
V
F
K
C
Site 27
Y277
F
T
E
E
D
Q
D
Y
L
E
G
L
L
T
K
Site 28
T283
D
Y
L
E
G
L
L
T
K
P
I
V
K
K
Y
Site 29
Y290
T
K
P
I
V
K
K
Y
C
L
D
V
I
E
G
Site 30
Y303
E
G
A
L
Q
M
R
Y
G
D
L
L
Y
K
S
Site 31
Y308
M
R
Y
G
D
L
L
Y
K
S
L
V
P
V
P
Site 32
S310
Y
G
D
L
L
Y
K
S
L
V
P
V
P
N
S
Site 33
S317
S
L
V
P
V
P
N
S
S
S
S
S
S
S
S
Site 34
S318
L
V
P
V
P
N
S
S
S
S
S
S
S
S
N
Site 35
S319
V
P
V
P
N
S
S
S
S
S
S
S
S
N
S
Site 36
S320
P
V
P
N
S
S
S
S
S
S
S
S
N
S
L
Site 37
S321
V
P
N
S
S
S
S
S
S
S
S
N
S
L
V
Site 38
S322
P
N
S
S
S
S
S
S
S
S
N
S
L
V
S
Site 39
S323
N
S
S
S
S
S
S
S
S
N
S
L
V
S
A
Site 40
S324
S
S
S
S
S
S
S
S
N
S
L
V
S
A
A
Site 41
S326
S
S
S
S
S
S
N
S
L
V
S
A
A
E
N
Site 42
S329
S
S
S
N
S
L
V
S
A
A
E
N
P
P
Q
Site 43
Y359
P
R
D
P
F
L
C
Y
D
P
Y
S
G
D
I
Site 44
Y362
P
F
L
C
Y
D
P
Y
S
G
D
I
Y
T
M
Site 45
Y367
D
P
Y
S
G
D
I
Y
T
M
P
S
P
L
T
Site 46
T368
P
Y
S
G
D
I
Y
T
M
P
S
P
L
T
S
Site 47
S371
G
D
I
Y
T
M
P
S
P
L
T
S
F
A
H
Site 48
S375
T
M
P
S
P
L
T
S
F
A
H
T
K
T
V
Site 49
T379
P
L
T
S
F
A
H
T
K
T
V
T
S
S
A
Site 50
S385
H
T
K
T
V
T
S
S
A
V
C
V
S
P
D
Site 51
Y396
V
S
P
D
H
D
I
Y
L
A
A
Q
P
R
K
Site 52
Y408
P
R
K
D
L
W
V
Y
K
P
A
Q
N
S
W
Site 53
Y438
A
Y
L
N
G
Y
I
Y
I
L
G
G
R
D
P
Site 54
T447
L
G
G
R
D
P
I
T
G
V
K
L
K
E
V
Site 55
Y457
K
L
K
E
V
E
C
Y
S
V
Q
R
N
Q
W
Site 56
S513
N
C
A
S
L
K
R
S
D
F
Q
E
A
C
V
Site 57
Y537
D
I
P
V
M
K
V
Y
N
P
A
R
G
E
W
Site 58
S548
R
G
E
W
R
R
I
S
N
I
P
L
D
S
E
Site 59
Y559
L
D
S
E
T
H
N
Y
Q
I
V
N
H
D
Q
Site 60
S573
Q
K
L
L
L
I
T
S
T
T
P
Q
W
K
K
Site 61
T575
L
L
L
I
T
S
T
T
P
Q
W
K
K
N
R
Site 62
Y586
K
K
N
R
V
T
V
Y
E
Y
D
T
R
E
D
Site 63
Y588
N
R
V
T
V
Y
E
Y
D
T
R
E
D
Q
W
Site 64
S628
S
C
L
E
P
G
Q
S
F
I
T
E
E
D
D
Site 65
S638
T
E
E
D
D
A
R
S
E
S
S
T
E
W
D
Site 66
S640
E
D
D
A
R
S
E
S
S
T
E
W
D
L
D
Site 67
T642
D
A
R
S
E
S
S
T
E
W
D
L
D
G
F
Site 68
S650
E
W
D
L
D
G
F
S
E
L
D
S
E
S
G
Site 69
S654
D
G
F
S
E
L
D
S
E
S
G
S
S
S
S
Site 70
S656
F
S
E
L
D
S
E
S
G
S
S
S
S
F
S
Site 71
S658
E
L
D
S
E
S
G
S
S
S
S
F
S
D
D
Site 72
S659
L
D
S
E
S
G
S
S
S
S
F
S
D
D
E
Site 73
S660
D
S
E
S
G
S
S
S
S
F
S
D
D
E
V
Site 74
S661
S
E
S
G
S
S
S
S
F
S
D
D
E
V
W
Site 75
S663
S
G
S
S
S
S
F
S
D
D
E
V
W
V
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation