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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PCNP
Full Name:
PEST proteolytic signal-containing nuclear protein
Alias:
PEST-containing nuclear protein
Type:
Uncharacterized protein
Mass (Da):
18925
Number AA:
178
UniProt ID:
Q8WW12
International Prot ID:
IPI00291608
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0043226
GO:0043227
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0005515
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
GO:0007049
GO:0043161
GO:0016567
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S14
G
D
E
K
P
E
K
S
Q
R
A
G
A
A
G
Site 2
T33
E
A
E
K
P
V
K
T
K
T
V
S
S
S
N
Site 3
T35
E
K
P
V
K
T
K
T
V
S
S
S
N
G
G
Site 4
S37
P
V
K
T
K
T
V
S
S
S
N
G
G
E
S
Site 5
S39
K
T
K
T
V
S
S
S
N
G
G
E
S
S
S
Site 6
S44
S
S
S
N
G
G
E
S
S
S
R
S
A
E
K
Site 7
S45
S
S
N
G
G
E
S
S
S
R
S
A
E
K
R
Site 8
S46
S
N
G
G
E
S
S
S
R
S
A
E
K
R
S
Site 9
S48
G
G
E
S
S
S
R
S
A
E
K
R
S
A
E
Site 10
T66
A
D
L
P
T
K
P
T
K
I
S
K
F
G
F
Site 11
S69
P
T
K
P
T
K
I
S
K
F
G
F
A
I
G
Site 12
S77
K
F
G
F
A
I
G
S
Q
T
T
K
K
A
S
Site 13
S84
S
Q
T
T
K
K
A
S
A
I
S
I
K
L
G
Site 14
S87
T
K
K
A
S
A
I
S
I
K
L
G
S
S
K
Site 15
S93
I
S
I
K
L
G
S
S
K
P
K
E
T
V
P
Site 16
T101
K
P
K
E
T
V
P
T
L
A
P
K
T
L
S
Site 17
T106
V
P
T
L
A
P
K
T
L
S
V
A
A
A
F
Site 18
S108
T
L
A
P
K
T
L
S
V
A
A
A
F
N
E
Site 19
S119
A
F
N
E
D
E
D
S
E
P
E
E
M
P
P
Site 20
T139
M
K
N
I
G
R
D
T
P
T
S
A
G
P
N
Site 21
T141
N
I
G
R
D
T
P
T
S
A
G
P
N
S
F
Site 22
S142
I
G
R
D
T
P
T
S
A
G
P
N
S
F
N
Site 23
S147
P
T
S
A
G
P
N
S
F
N
K
G
K
H
G
Site 24
S156
N
K
G
K
H
G
F
S
D
N
Q
K
L
W
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation