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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LIPH
Full Name:
Lipase member H
Alias:
LPD lipase-related protein;Membrane-associated phosphatidic acid-selective phospholipase A1-alpha;Phospholipase A1 member B
Type:
Mass (Da):
50859
Number AA:
451
UniProt ID:
Q8WWY8
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S16
S
L
L
C
L
S
R
S
D
A
E
E
T
C
P
Site 2
T21
S
R
S
D
A
E
E
T
C
P
S
F
T
R
L
Site 3
S24
D
A
E
E
T
C
P
S
F
T
R
L
S
F
H
Site 4
S29
C
P
S
F
T
R
L
S
F
H
S
A
V
V
G
Site 5
T47
N
V
R
L
M
L
Y
T
R
K
N
L
T
C
A
Site 6
T56
K
N
L
T
C
A
Q
T
I
N
S
S
A
F
G
Site 7
S83
H
G
F
R
P
T
G
S
P
P
V
W
M
D
D
Site 8
Y117
R
G
A
T
T
L
I
Y
T
H
A
S
S
K
T
Site 9
T118
G
A
T
T
L
I
Y
T
H
A
S
S
K
T
R
Site 10
S122
L
I
Y
T
H
A
S
S
K
T
R
K
V
A
M
Site 11
Y167
S
G
F
V
G
E
M
Y
D
G
W
L
G
R
I
Site 12
T175
D
G
W
L
G
R
I
T
G
L
D
P
A
G
P
Site 13
S196
H
Q
D
R
L
D
P
S
D
A
Q
F
V
D
V
Site 14
S206
Q
F
V
D
V
I
H
S
D
T
D
A
L
G
Y
Site 15
T208
V
D
V
I
H
S
D
T
D
A
L
G
Y
K
E
Site 16
Y213
S
D
T
D
A
L
G
Y
K
E
P
L
G
N
I
Site 17
Y223
P
L
G
N
I
D
F
Y
P
N
G
G
L
D
Q
Site 18
T236
D
Q
P
G
C
P
K
T
I
L
G
G
F
Q
Y
Site 19
Y243
T
I
L
G
G
F
Q
Y
F
K
C
D
H
Q
R
Site 20
S251
F
K
C
D
H
Q
R
S
V
Y
L
Y
L
S
S
Site 21
Y253
C
D
H
Q
R
S
V
Y
L
Y
L
S
S
L
R
Site 22
Y255
H
Q
R
S
V
Y
L
Y
L
S
S
L
R
E
S
Site 23
S257
R
S
V
Y
L
Y
L
S
S
L
R
E
S
C
T
Site 24
S262
Y
L
S
S
L
R
E
S
C
T
I
T
A
Y
P
Site 25
T264
S
S
L
R
E
S
C
T
I
T
A
Y
P
C
D
Site 26
T266
L
R
E
S
C
T
I
T
A
Y
P
C
D
S
Y
Site 27
Y268
E
S
C
T
I
T
A
Y
P
C
D
S
Y
Q
D
Site 28
Y273
T
A
Y
P
C
D
S
Y
Q
D
Y
R
N
G
K
Site 29
Y276
P
C
D
S
Y
Q
D
Y
R
N
G
K
C
V
S
Site 30
S283
Y
R
N
G
K
C
V
S
C
G
T
S
Q
K
E
Site 31
S287
K
C
V
S
C
G
T
S
Q
K
E
S
C
P
L
Site 32
S291
C
G
T
S
Q
K
E
S
C
P
L
L
G
Y
Y
Site 33
Y297
E
S
C
P
L
L
G
Y
Y
A
D
N
W
K
D
Site 34
Y298
S
C
P
L
L
G
Y
Y
A
D
N
W
K
D
H
Site 35
T314
R
G
K
D
P
P
M
T
K
A
F
F
D
T
A
Site 36
T320
M
T
K
A
F
F
D
T
A
E
E
S
P
F
C
Site 37
T348
N
V
R
R
G
D
I
T
I
K
L
R
D
K
A
Site 38
T368
S
K
I
N
H
E
P
T
T
F
Q
K
Y
H
Q
Site 39
Y373
E
P
T
T
F
Q
K
Y
H
Q
V
S
L
L
A
Site 40
S400
S
L
M
F
S
T
G
S
L
I
G
P
R
Y
K
Site 41
Y406
G
S
L
I
G
P
R
Y
K
L
R
I
L
R
M
Site 42
S417
I
L
R
M
K
L
R
S
L
A
H
P
E
R
P
Site 43
Y429
E
R
P
Q
L
C
R
Y
D
L
V
L
M
E
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation