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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ABCA10
Full Name:
ATP-binding cassette sub-family A member 10
Alias:
Type:
Transport protein, ABC
Mass (Da):
175746
Number AA:
1543
UniProt ID:
Q8WWZ4
International Prot ID:
IPI00384874
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0016887
PhosphoSite+
KinaseNET
Biological Process:
GO:0006810
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T14
A
S
F
M
K
G
R
T
V
I
G
T
P
D
E
Site 2
T18
K
G
R
T
V
I
G
T
P
D
E
E
T
M
D
Site 3
T23
I
G
T
P
D
E
E
T
M
D
I
E
L
P
K
Site 4
Y32
D
I
E
L
P
K
K
Y
H
E
M
V
G
V
I
Site 5
Y54
R
L
K
F
N
W
G
Y
R
I
P
V
I
K
E
Site 6
S107
I
E
V
T
T
N
H
S
V
M
E
E
L
T
S
Site 7
S152
S
S
F
I
Y
F
A
S
L
N
V
A
R
E
R
Site 8
T167
G
K
F
K
K
L
M
T
V
M
G
L
R
E
S
Site 9
S295
T
H
L
D
N
Y
L
S
G
V
I
F
P
D
P
Site 10
S303
G
V
I
F
P
D
P
S
G
D
S
Y
K
M
I
Site 11
S306
F
P
D
P
S
G
D
S
Y
K
M
I
A
T
F
Site 12
Y307
P
D
P
S
G
D
S
Y
K
M
I
A
T
F
F
Site 13
S343
D
K
D
G
H
G
D
S
P
L
F
F
L
K
S
Site 14
S350
S
P
L
F
F
L
K
S
S
F
W
S
K
H
Q
Site 15
S351
P
L
F
F
L
K
S
S
F
W
S
K
H
Q
N
Site 16
S373
N
E
I
N
P
E
H
S
S
D
D
S
F
E
P
Site 17
S374
E
I
N
P
E
H
S
S
D
D
S
F
E
P
V
Site 18
S377
P
E
H
S
S
D
D
S
F
E
P
V
S
P
E
Site 19
S382
D
D
S
F
E
P
V
S
P
E
F
H
G
K
E
Site 20
Y400
I
R
N
V
I
K
E
Y
N
G
K
T
G
K
V
Site 21
T423
D
I
Y
E
G
Q
I
T
A
I
L
G
H
N
G
Site 22
S434
G
H
N
G
A
G
K
S
T
L
L
N
I
L
S
Site 23
S450
L
S
V
S
T
E
G
S
A
T
I
Y
N
T
Q
Site 24
T452
V
S
T
E
G
S
A
T
I
Y
N
T
Q
L
S
Site 25
Y454
T
E
G
S
A
T
I
Y
N
T
Q
L
S
E
I
Site 26
T485
N
F
Q
F
D
F
L
T
V
R
E
N
L
R
V
Site 27
S519
I
M
E
L
D
M
Q
S
I
Q
D
I
I
A
K
Site 28
S562
T
A
G
L
D
P
F
S
R
H
R
V
W
S
L
Site 29
S568
F
S
R
H
R
V
W
S
L
L
K
E
H
K
V
Site 30
S600
A
D
R
K
V
F
L
S
N
G
K
L
K
C
A
Site 31
S609
G
K
L
K
C
A
G
S
S
L
F
L
K
R
K
Site 32
T633
H
R
N
E
M
C
D
T
E
K
I
T
S
L
I
Site 33
S638
C
D
T
E
K
I
T
S
L
I
K
Q
H
I
P
Site 34
Y659
E
S
E
E
K
L
V
Y
S
L
P
L
E
K
T
Site 35
T666
Y
S
L
P
L
E
K
T
N
K
F
P
D
L
Y
Site 36
Y673
T
N
K
F
P
D
L
Y
S
D
L
D
K
C
S
Site 37
S674
N
K
F
P
D
L
Y
S
D
L
D
K
C
S
D
Site 38
Y687
S
D
Q
G
I
R
N
Y
A
V
S
V
T
S
L
Site 39
S705
F
L
N
L
E
G
K
S
A
I
D
E
P
D
F
Site 40
T726
K
I
H
V
T
R
N
T
G
D
E
S
E
M
E
Site 41
S730
T
R
N
T
G
D
E
S
E
M
E
Q
V
L
C
Site 42
S738
E
M
E
Q
V
L
C
S
L
P
E
T
R
K
A
Site 43
T742
V
L
C
S
L
P
E
T
R
K
A
V
S
S
A
Site 44
S748
E
T
R
K
A
V
S
S
A
A
L
W
R
R
Q
Site 45
Y757
A
L
W
R
R
Q
I
Y
A
V
A
T
L
R
F
Site 46
T761
R
Q
I
Y
A
V
A
T
L
R
F
L
K
L
R
Site 47
Y795
I
I
L
E
K
I
M
Y
K
V
T
R
E
T
H
Site 48
Y811
W
E
F
S
P
S
M
Y
F
L
S
L
E
Q
I
Site 49
S814
S
P
S
M
Y
F
L
S
L
E
Q
I
P
K
T
Site 50
S861
D
F
R
N
R
N
G
S
D
D
P
S
Y
N
G
Site 51
S865
R
N
G
S
D
D
P
S
Y
N
G
A
I
I
V
Site 52
Y866
N
G
S
D
D
P
S
Y
N
G
A
I
I
V
S
Site 53
Y879
V
S
G
D
Q
K
D
Y
R
F
S
V
A
C
N
Site 54
S882
D
Q
K
D
Y
R
F
S
V
A
C
N
T
K
K
Site 55
T887
R
F
S
V
A
C
N
T
K
K
L
N
C
F
P
Site 56
T916
N
F
T
E
L
I
Q
T
E
S
T
S
F
S
R
Site 57
S918
T
E
L
I
Q
T
E
S
T
S
F
S
R
D
D
Site 58
S920
L
I
Q
T
E
S
T
S
F
S
R
D
D
I
V
Site 59
S922
Q
T
E
S
T
S
F
S
R
D
D
I
V
L
D
Site 60
S954
S
P
F
I
G
M
S
S
I
S
D
Y
K
K
N
Site 61
Y958
G
M
S
S
I
S
D
Y
K
K
N
V
Q
S
Q
Site 62
S964
D
Y
K
K
N
V
Q
S
Q
L
W
I
S
G
L
Site 63
S1103
D
F
M
R
N
L
D
S
L
D
N
R
I
N
E
Site 64
Y1140
I
R
C
L
E
M
K
Y
G
N
E
I
M
N
K
Site 65
S1154
K
D
P
V
F
R
I
S
P
R
S
R
E
T
H
Site 66
S1157
V
F
R
I
S
P
R
S
R
E
T
H
P
N
P
Site 67
T1160
I
S
P
R
S
R
E
T
H
P
N
P
E
E
P
Site 68
T1197
L
E
E
E
P
V
I
T
A
S
C
L
H
K
E
Site 69
Y1206
S
C
L
H
K
E
Y
Y
E
T
K
K
S
C
F
Site 70
T1208
L
H
K
E
Y
Y
E
T
K
K
S
C
F
S
T
Site 71
S1211
E
Y
Y
E
T
K
K
S
C
F
S
T
R
K
K
Site 72
S1214
E
T
K
K
S
C
F
S
T
R
K
K
K
I
A
Site 73
T1215
T
K
K
S
C
F
S
T
R
K
K
K
I
A
I
Site 74
S1226
K
I
A
I
R
N
V
S
F
C
V
K
K
G
E
Site 75
S1246
G
H
N
G
A
G
K
S
T
S
I
K
M
I
T
Site 76
S1248
N
G
A
G
K
S
T
S
I
K
M
I
T
G
C
Site 77
T1253
S
T
S
I
K
M
I
T
G
C
T
K
P
T
A
Site 78
S1271
V
L
Q
G
S
R
A
S
V
R
Q
Q
H
D
N
Site 79
S1279
V
R
Q
Q
H
D
N
S
L
K
F
L
G
Y
C
Site 80
Y1285
N
S
L
K
F
L
G
Y
C
P
Q
E
N
S
L
Site 81
S1291
G
Y
C
P
Q
E
N
S
L
W
P
K
L
T
M
Site 82
T1297
N
S
L
W
P
K
L
T
M
K
E
H
L
E
L
Site 83
S1319
G
K
E
D
A
A
L
S
I
S
R
L
V
E
A
Site 84
T1339
Q
L
K
A
P
V
K
T
L
S
E
G
I
K
R
Site 85
S1341
K
A
P
V
K
T
L
S
E
G
I
K
R
K
L
Site 86
T1385
M
W
Q
I
L
Q
A
T
V
K
N
K
E
R
G
Site 87
T1393
V
K
N
K
E
R
G
T
L
L
T
T
H
Y
M
Site 88
T1396
K
E
R
G
T
L
L
T
T
H
Y
M
S
E
A
Site 89
T1397
E
R
G
T
L
L
T
T
H
Y
M
S
E
A
E
Site 90
S1415
D
R
M
A
M
M
V
S
G
T
L
R
C
I
G
Site 91
S1423
G
T
L
R
C
I
G
S
I
Q
H
L
K
N
K
Site 92
Y1435
K
N
K
F
G
R
D
Y
L
L
E
I
K
M
K
Site 93
S1468
A
A
W
Q
E
R
Y
S
S
L
M
A
Y
K
L
Site 94
S1469
A
W
Q
E
R
Y
S
S
L
M
A
Y
K
L
P
Site 95
Y1473
R
Y
S
S
L
M
A
Y
K
L
P
V
E
D
V
Site 96
S1484
V
E
D
V
H
P
L
S
R
A
F
F
K
L
E
Site 97
T1496
K
L
E
A
M
K
Q
T
F
N
L
E
E
Y
S
Site 98
S1503
T
F
N
L
E
E
Y
S
L
S
Q
A
T
L
E
Site 99
S1505
N
L
E
E
Y
S
L
S
Q
A
T
L
E
Q
V
Site 100
T1532
V
D
D
K
I
D
T
T
V
E
W
K
L
L
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation