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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PALLD
Full Name:
Palladin
Alias:
Palladin: Sarcoma antigen NY-SAR-77: SIH002: Palladin: Sarcoma antigen NY-SAR-77: SIH002: Palladin: Sarcoma antigen NY-SAR-77: SIH002: Palladin: Sarcoma antigen NY-SAR-77: SIH002: Palladin: Sarcoma antigen NY-SAR-77: SIH002: Palladin: Sarcoma antigen NY-SAR-77: SIH002; Sarcoma antigen NY-SAR-77
Type:
Cytoskeletal protein
Mass (Da):
150537
Number AA:
1383
UniProt ID:
Q8WX93
International Prot ID:
not found
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005884
GO:0005737
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003779
GO:0051371
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0007010
GO:0007010
GO:0009987
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
S
G
T
S
S
H
E
S
F
Y
D
S
Site 2
S9
S
G
T
S
S
H
E
S
F
Y
D
S
L
S
D
Site 3
Y11
T
S
S
H
E
S
F
Y
D
S
L
S
D
M
Q
Site 4
S13
S
H
E
S
F
Y
D
S
L
S
D
M
Q
E
E
Site 5
S15
E
S
F
Y
D
S
L
S
D
M
Q
E
E
S
K
Site 6
T24
M
Q
E
E
S
K
N
T
D
F
F
P
G
L
S
Site 7
S31
T
D
F
F
P
G
L
S
A
F
L
S
Q
E
E
Site 8
S35
P
G
L
S
A
F
L
S
Q
E
E
I
N
K
S
Site 9
S42
S
Q
E
E
I
N
K
S
L
D
L
A
R
R
A
Site 10
S53
A
R
R
A
I
A
D
S
E
T
E
D
F
D
S
Site 11
T55
R
A
I
A
D
S
E
T
E
D
F
D
S
E
K
Site 12
S60
S
E
T
E
D
F
D
S
E
K
E
I
S
Q
I
Site 13
S65
F
D
S
E
K
E
I
S
Q
I
F
S
T
S
P
Site 14
S69
K
E
I
S
Q
I
F
S
T
S
P
A
S
L
C
Site 15
S74
I
F
S
T
S
P
A
S
L
C
E
H
P
S
H
Site 16
S80
A
S
L
C
E
H
P
S
H
K
E
T
K
L
G
Site 17
T84
E
H
P
S
H
K
E
T
K
L
G
E
H
A
S
Site 18
S91
T
K
L
G
E
H
A
S
R
R
P
Q
D
N
R
Site 19
S99
R
R
P
Q
D
N
R
S
T
P
V
Q
P
L
A
Site 20
T100
R
P
Q
D
N
R
S
T
P
V
Q
P
L
A
E
Site 21
T110
Q
P
L
A
E
K
Q
T
K
S
I
S
S
P
V
Site 22
S112
L
A
E
K
Q
T
K
S
I
S
S
P
V
S
K
Site 23
S114
E
K
Q
T
K
S
I
S
S
P
V
S
K
R
K
Site 24
S115
K
Q
T
K
S
I
S
S
P
V
S
K
R
K
P
Site 25
S118
K
S
I
S
S
P
V
S
K
R
K
P
A
M
S
Site 26
S125
S
K
R
K
P
A
M
S
P
L
L
T
R
P
S
Site 27
T129
P
A
M
S
P
L
L
T
R
P
S
Y
I
R
S
Site 28
S132
S
P
L
L
T
R
P
S
Y
I
R
S
L
R
K
Site 29
Y133
P
L
L
T
R
P
S
Y
I
R
S
L
R
K
A
Site 30
S136
T
R
P
S
Y
I
R
S
L
R
K
A
E
K
R
Site 31
T147
A
E
K
R
G
A
K
T
P
S
T
N
V
K
P
Site 32
S149
K
R
G
A
K
T
P
S
T
N
V
K
P
K
T
Site 33
T150
R
G
A
K
T
P
S
T
N
V
K
P
K
T
P
Site 34
T156
S
T
N
V
K
P
K
T
P
H
Q
R
K
G
G
Site 35
S166
Q
R
K
G
G
P
Q
S
Q
L
C
D
K
A
A
Site 36
S192
A
A
K
P
R
N
R
S
P
N
G
E
S
S
S
Site 37
S197
N
R
S
P
N
G
E
S
S
S
P
D
S
G
Y
Site 38
S198
R
S
P
N
G
E
S
S
S
P
D
S
G
Y
L
Site 39
S199
S
P
N
G
E
S
S
S
P
D
S
G
Y
L
S
Site 40
S202
G
E
S
S
S
P
D
S
G
Y
L
S
P
K
N
Site 41
Y204
S
S
S
P
D
S
G
Y
L
S
P
K
N
Q
P
Site 42
S206
S
P
D
S
G
Y
L
S
P
K
N
Q
P
S
A
Site 43
S212
L
S
P
K
N
Q
P
S
A
L
L
S
A
S
A
Site 44
S216
N
Q
P
S
A
L
L
S
A
S
A
S
Q
S
P
Site 45
S218
P
S
A
L
L
S
A
S
A
S
Q
S
P
M
E
Site 46
S220
A
L
L
S
A
S
A
S
Q
S
P
M
E
D
Q
Site 47
S222
L
S
A
S
A
S
Q
S
P
M
E
D
Q
G
E
Site 48
S236
E
M
E
R
E
V
K
S
P
G
A
R
H
C
Y
Site 49
Y243
S
P
G
A
R
H
C
Y
Q
D
N
Q
D
L
A
Site 50
S257
A
V
P
H
N
R
K
S
H
P
Q
P
H
S
A
Site 51
S263
K
S
H
P
Q
P
H
S
A
L
H
F
P
A
A
Site 52
S279
R
F
I
Q
K
L
R
S
Q
E
V
A
E
G
S
Site 53
Y289
V
A
E
G
S
R
V
Y
L
E
C
R
V
T
G
Site 54
T295
V
Y
L
E
C
R
V
T
G
N
P
T
P
R
V
Site 55
T299
C
R
V
T
G
N
P
T
P
R
V
R
W
F
C
Site 56
T314
E
G
K
E
L
H
N
T
P
D
I
Q
I
H
C
Site 57
T339
A
E
A
F
E
D
D
T
G
R
Y
T
C
L
A
Site 58
T343
E
D
D
T
G
R
Y
T
C
L
A
T
N
P
S
Site 59
S350
T
C
L
A
T
N
P
S
G
S
D
T
T
S
A
Site 60
S352
L
A
T
N
P
S
G
S
D
T
T
S
A
E
V
Site 61
T354
T
N
P
S
G
S
D
T
T
S
A
E
V
F
I
Site 62
S356
P
S
G
S
D
T
T
S
A
E
V
F
I
E
G
Site 63
S365
E
V
F
I
E
G
A
S
S
T
D
S
D
S
E
Site 64
S366
V
F
I
E
G
A
S
S
T
D
S
D
S
E
S
Site 65
T367
F
I
E
G
A
S
S
T
D
S
D
S
E
S
L
Site 66
S369
E
G
A
S
S
T
D
S
D
S
E
S
L
A
F
Site 67
S371
A
S
S
T
D
S
D
S
E
S
L
A
F
K
S
Site 68
S373
S
T
D
S
D
S
E
S
L
A
F
K
S
R
A
Site 69
T390
M
P
Q
A
Q
K
K
T
T
S
V
S
L
T
I
Site 70
S392
Q
A
Q
K
K
T
T
S
V
S
L
T
I
G
S
Site 71
S394
Q
K
K
T
T
S
V
S
L
T
I
G
S
S
S
Site 72
T396
K
T
T
S
V
S
L
T
I
G
S
S
S
P
K
Site 73
S401
S
L
T
I
G
S
S
S
P
K
T
G
V
T
T
Site 74
S423
V
P
V
Q
Q
V
H
S
P
T
S
Y
L
C
R
Site 75
S426
Q
Q
V
H
S
P
T
S
Y
L
C
R
P
D
G
Site 76
Y427
Q
V
H
S
P
T
S
Y
L
C
R
P
D
G
T
Site 77
T435
L
C
R
P
D
G
T
T
T
A
Y
F
P
P
V
Site 78
Y438
P
D
G
T
T
T
A
Y
F
P
P
V
F
T
K
Site 79
T450
F
T
K
E
L
Q
N
T
A
V
A
E
G
Q
V
Site 80
S479
V
Q
W
F
R
Q
G
S
E
I
Q
D
S
P
D
Site 81
S484
Q
G
S
E
I
Q
D
S
P
D
F
R
I
L
Q
Site 82
S496
I
L
Q
K
K
P
R
S
T
A
E
P
E
E
I
Site 83
T497
L
Q
K
K
P
R
S
T
A
E
P
E
E
I
C
Site 84
S522
D
A
G
I
F
T
C
S
A
R
N
D
Y
G
S
Site 85
Y527
T
C
S
A
R
N
D
Y
G
S
A
T
S
T
A
Site 86
S529
S
A
R
N
D
Y
G
S
A
T
S
T
A
Q
L
Site 87
T533
D
Y
G
S
A
T
S
T
A
Q
L
V
V
T
S
Site 88
S547
S
A
N
T
E
N
C
S
Y
E
S
M
G
E
S
Site 89
Y548
A
N
T
E
N
C
S
Y
E
S
M
G
E
S
N
Site 90
S573
P
P
I
L
E
T
S
S
L
E
L
A
S
K
K
Site 91
S578
T
S
S
L
E
L
A
S
K
K
P
S
E
I
Q
Site 92
S582
E
L
A
S
K
K
P
S
E
I
Q
Q
V
N
N
Site 93
S595
N
N
P
E
L
G
L
S
R
A
A
L
Q
M
Q
Site 94
T610
F
N
A
A
E
R
E
T
S
G
V
H
P
S
R
Site 95
S611
N
A
A
E
R
E
T
S
G
V
H
P
S
R
G
Site 96
S616
E
T
S
G
V
H
P
S
R
G
V
N
G
L
I
Site 97
S629
L
I
N
G
K
A
N
S
N
K
S
L
P
T
P
Site 98
S632
G
K
A
N
S
N
K
S
L
P
T
P
A
V
L
Site 99
T635
N
S
N
K
S
L
P
T
P
A
V
L
L
S
P
Site 100
S641
P
T
P
A
V
L
L
S
P
T
K
E
P
P
P
Site 101
T643
P
A
V
L
L
S
P
T
K
E
P
P
P
L
L
Site 102
S684
Q
P
P
P
A
P
R
S
A
P
P
S
P
P
F
Site 103
S688
A
P
R
S
A
P
P
S
P
P
F
P
P
P
P
Site 104
T704
F
P
E
L
A
A
C
T
P
P
A
S
P
E
P
Site 105
S708
A
A
C
T
P
P
A
S
P
E
P
M
S
A
L
Site 106
S713
P
A
S
P
E
P
M
S
A
L
A
S
R
S
A
Site 107
S717
E
P
M
S
A
L
A
S
R
S
A
P
A
M
Q
Site 108
S719
M
S
A
L
A
S
R
S
A
P
A
M
Q
S
S
Site 109
S725
R
S
A
P
A
M
Q
S
S
G
S
F
N
Y
A
Site 110
S726
S
A
P
A
M
Q
S
S
G
S
F
N
Y
A
R
Site 111
S728
P
A
M
Q
S
S
G
S
F
N
Y
A
R
P
K
Site 112
Y731
Q
S
S
G
S
F
N
Y
A
R
P
K
Q
F
I
Site 113
S747
A
Q
N
L
G
P
A
S
G
H
G
T
P
A
S
Site 114
T751
G
P
A
S
G
H
G
T
P
A
S
S
P
S
S
Site 115
S754
S
G
H
G
T
P
A
S
S
P
S
S
S
S
L
Site 116
S755
G
H
G
T
P
A
S
S
P
S
S
S
S
L
P
Site 117
S757
G
T
P
A
S
S
P
S
S
S
S
L
P
S
P
Site 118
S758
T
P
A
S
S
P
S
S
S
S
L
P
S
P
M
Site 119
S759
P
A
S
S
P
S
S
S
S
L
P
S
P
M
S
Site 120
S760
A
S
S
P
S
S
S
S
L
P
S
P
M
S
P
Site 121
S763
P
S
S
S
S
L
P
S
P
M
S
P
T
P
R
Site 122
S766
S
S
L
P
S
P
M
S
P
T
P
R
Q
F
G
Site 123
T768
L
P
S
P
M
S
P
T
P
R
Q
F
G
R
A
Site 124
S794
E
P
E
A
P
W
G
S
S
S
P
S
P
P
P
Site 125
S795
P
E
A
P
W
G
S
S
S
P
S
P
P
P
P
Site 126
S796
E
A
P
W
G
S
S
S
P
S
P
P
P
P
P
Site 127
S798
P
W
G
S
S
S
P
S
P
P
P
P
P
P
P
Site 128
T810
P
P
P
V
F
S
P
T
A
A
F
P
V
P
D
Site 129
S830
P
P
P
P
P
L
P
S
P
G
Q
A
S
H
C
Site 130
S835
L
P
S
P
G
Q
A
S
H
C
S
S
P
A
T
Site 131
S838
P
G
Q
A
S
H
C
S
S
P
A
T
R
F
G
Site 132
S839
G
Q
A
S
H
C
S
S
P
A
T
R
F
G
H
Site 133
T842
S
H
C
S
S
P
A
T
R
F
G
H
S
Q
T
Site 134
S847
P
A
T
R
F
G
H
S
Q
T
P
A
A
F
L
Site 135
T849
T
R
F
G
H
S
Q
T
P
A
A
F
L
S
A
Site 136
T877
L
G
L
P
K
G
V
T
P
A
G
F
P
K
K
Site 137
S886
A
G
F
P
K
K
A
S
R
T
A
R
I
A
S
Site 138
S893
S
R
T
A
R
I
A
S
D
E
E
I
Q
G
T
Site 139
T900
S
D
E
E
I
Q
G
T
K
D
A
V
I
Q
D
Site 140
T927
N
N
G
Q
P
R
L
T
Y
E
E
R
M
A
R
Site 141
Y928
N
G
Q
P
R
L
T
Y
E
E
R
M
A
R
R
Site 142
S941
R
R
L
L
G
A
D
S
A
T
V
F
N
I
Q
Site 143
T954
I
Q
E
P
E
E
E
T
A
N
Q
E
Y
K
V
Site 144
Y959
E
E
T
A
N
Q
E
Y
K
V
S
S
C
E
Q
Site 145
S962
A
N
Q
E
Y
K
V
S
S
C
E
Q
R
L
I
Site 146
S970
S
C
E
Q
R
L
I
S
E
I
E
Y
R
L
E
Site 147
Y974
R
L
I
S
E
I
E
Y
R
L
E
R
S
P
V
Site 148
S979
I
E
Y
R
L
E
R
S
P
V
D
E
S
G
D
Site 149
S984
E
R
S
P
V
D
E
S
G
D
E
V
Q
Y
G
Site 150
Y990
E
S
G
D
E
V
Q
Y
G
D
V
P
V
E
N
Site 151
Y1010
F
E
M
K
L
K
H
Y
K
I
F
E
G
M
P
Site 152
T1021
E
G
M
P
V
T
F
T
C
R
V
A
G
N
P
Site 153
Y1033
G
N
P
K
P
K
I
Y
W
F
K
D
G
K
Q
Site 154
S1042
F
K
D
G
K
Q
I
S
P
K
S
D
H
Y
T
Site 155
S1045
G
K
Q
I
S
P
K
S
D
H
Y
T
I
Q
R
Site 156
Y1048
I
S
P
K
S
D
H
Y
T
I
Q
R
D
L
D
Site 157
T1049
S
P
K
S
D
H
Y
T
I
Q
R
D
L
D
G
Site 158
T1057
I
Q
R
D
L
D
G
T
C
S
L
H
T
T
A
Site 159
S1059
R
D
L
D
G
T
C
S
L
H
T
T
A
S
T
Site 160
T1063
G
T
C
S
L
H
T
T
A
S
T
L
D
D
D
Site 161
S1065
C
S
L
H
T
T
A
S
T
L
D
D
D
G
N
Site 162
T1066
S
L
H
T
T
A
S
T
L
D
D
D
G
N
Y
Site 163
Y1073
T
L
D
D
D
G
N
Y
T
I
M
A
A
N
P
Site 164
S1085
A
N
P
Q
G
R
I
S
C
T
G
R
L
M
V
Site 165
S1101
A
V
N
Q
R
G
R
S
P
R
S
P
S
G
H
Site 166
S1104
Q
R
G
R
S
P
R
S
P
S
G
H
P
H
V
Site 167
S1106
G
R
S
P
R
S
P
S
G
H
P
H
V
R
R
Site 168
S1116
P
H
V
R
R
P
R
S
R
S
R
D
S
G
D
Site 169
S1118
V
R
R
P
R
S
R
S
R
D
S
G
D
E
N
Site 170
S1121
P
R
S
R
S
R
D
S
G
D
E
N
E
P
I
Site 171
T1145
L
Q
A
P
G
D
L
T
V
Q
E
G
K
L
C
Site 172
T1163
C
K
V
S
G
L
P
T
P
D
L
S
W
Q
L
Site 173
S1167
G
L
P
T
P
D
L
S
W
Q
L
D
G
K
P
Site 174
S1179
G
K
P
V
R
P
D
S
A
H
K
M
L
V
R
Site 175
Y1206
T
S
R
D
A
G
I
Y
T
C
I
A
T
N
R
Site 176
T1211
G
I
Y
T
C
I
A
T
N
R
A
G
Q
N
S
Site 177
S1218
T
N
R
A
G
Q
N
S
F
S
L
E
L
V
V
Site 178
T1243
F
I
E
K
L
Q
N
T
G
V
A
D
G
Y
P
Site 179
Y1249
N
T
G
V
A
D
G
Y
P
V
R
L
E
C
R
Site 180
S1273
F
W
K
K
E
N
E
S
L
T
H
S
T
D
R
Site 181
S1277
E
N
E
S
L
T
H
S
T
D
R
V
S
M
H
Site 182
T1278
N
E
S
L
T
H
S
T
D
R
V
S
M
H
Q
Site 183
T1307
K
E
D
A
G
W
Y
T
V
S
A
K
N
E
A
Site 184
Y1326
C
T
A
R
L
D
V
Y
T
Q
W
H
Q
Q
S
Site 185
T1327
T
A
R
L
D
V
Y
T
Q
W
H
Q
Q
S
Q
Site 186
S1333
Y
T
Q
W
H
Q
Q
S
Q
S
T
K
P
K
K
Site 187
S1344
K
P
K
K
V
R
P
S
A
S
R
Y
A
A
L
Site 188
S1346
K
K
V
R
P
S
A
S
R
Y
A
A
L
S
D
Site 189
Y1348
V
R
P
S
A
S
R
Y
A
A
L
S
D
Q
G
Site 190
S1352
A
S
R
Y
A
A
L
S
D
Q
G
L
D
I
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation