PhosphoNET

           
Protein Info 
   
Short Name:  SFRS12
Full Name:  Splicing factor, arginine/serine-rich 12
Alias:  DKFZp564B176; Serine-arginine-rich splicing regulatory protein 508; Serine-arginine-rich-splicing regulatory protein 86; SFR12; SRrp508; SRRP86
Type:  RNA processing
Mass (Da):  59380
Number AA:  508
UniProt ID:  Q8WXA9
International Prot ID:  IPI00103497
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005681     Uniprot OncoNet
Molecular Function:  GO:0003676  GO:0000166  GO:0005515 PhosphoSite+ KinaseNET
Biological Process:  GO:0008380  GO:0006397   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T21PTPNPLTTLGVSLSS
Site 2S28TLGVSLSSLGAIPAA
Site 3T67KIDEIRRTVYVGNLN
Site 4Y69DEIRRTVYVGNLNSQ
Site 5T79NLNSQTTTADQLLEF
Site 6T103VRMAGDETQPTRFAF
Site 7T106AGDETQPTRFAFVEF
Site 8S140RPLKINHSNNAIVKP
Site 9T151IVKPPEMTPQAAAKE
Site 10S171KRVREAQSFISAAIE
Site 11S181SAAIEPESGKSNERK
Site 12S184IEPESGKSNERKGGR
Site 13S192NERKGGRSRSHTRSK
Site 14S194RKGGRSRSHTRSKSR
Site 15T196GGRSRSHTRSKSRSS
Site 16S198RSRSHTRSKSRSSSK
Site 17S200RSHTRSKSRSSSKSH
Site 18S202HTRSKSRSSSKSHSR
Site 19S203TRSKSRSSSKSHSRR
Site 20S204RSKSRSSSKSHSRRK
Site 21S206KSRSSSKSHSRRKRS
Site 22S208RSSSKSHSRRKRSQS
Site 23S213SHSRRKRSQSKHRSR
Site 24S215SRRKRSQSKHRSRSH
Site 25S219RSQSKHRSRSHNRSR
Site 26S221QSKHRSRSHNRSRSR
Site 27S225RSRSHNRSRSRQKDR
Site 28S227RSHNRSRSRQKDRRR
Site 29S235RQKDRRRSKSPHKKR
Site 30S237KDRRRSKSPHKKRSK
Site 31S243KSPHKKRSKSRERRK
Site 32S245PHKKRSKSRERRKSR
Site 33S251KSRERRKSRSRSHSR
Site 34S253RERRKSRSRSHSRDK
Site 35S255RRKSRSRSHSRDKRK
Site 36S257KSRSRSHSRDKRKDT
Site 37T264SRDKRKDTREKIKEK
Site 38S348KEREKDRSKEIDEKR
Site 39S361KRKKDKKSRTPPRSY
Site 40T363KKDKKSRTPPRSYNA
Site 41S367KSRTPPRSYNASRRS
Site 42Y368SRTPPRSYNASRRSR
Site 43S371PPRSYNASRRSRSSS
Site 44S374SYNASRRSRSSSRER
Site 45S376NASRRSRSSSRERRR
Site 46S377ASRRSRSSSRERRRR
Site 47S378SRRSRSSSRERRRRR
Site 48S386RERRRRRSRSSSRSP
Site 49S388RRRRRSRSSSRSPRT
Site 50S389RRRRSRSSSRSPRTS
Site 51S390RRRSRSSSRSPRTSK
Site 52S392RSRSSSRSPRTSKTI
Site 53S396SSRSPRTSKTIKRKS
Site 54T398RSPRTSKTIKRKSSR
Site 55S403SKTIKRKSSRSPSPR
Site 56S404KTIKRKSSRSPSPRS
Site 57S406IKRKSSRSPSPRSRN
Site 58S408RKSSRSPSPRSRNKK
Site 59S411SRSPSPRSRNKKDKK
Site 60S427EKERDHISERRERER
Site 61S435ERRERERSTSMRKSS
Site 62T436RRERERSTSMRKSSN
Site 63S437RERERSTSMRKSSND
Site 64S441RSTSMRKSSNDRDGK
Site 65S442STSMRKSSNDRDGKE
Site 66T456EKLEKNSTSLKEKEH
Site 67S457KLEKNSTSLKEKEHN
Site 68S469EHNKEPDSSVSKEVD
Site 69S470HNKEPDSSVSKEVDD
Site 70T503LNEENLSTKTEAV__
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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