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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SRRP35
Full Name:
Serine/arginine-rich splicing factor 12
Alias:
35 kDa SR repressor; SRR35
Type:
mRNA splicing factor; Nucleoplasm, nucleus protein
Mass (Da):
30512
Number AA:
261
UniProt ID:
Q8WXF0
International Prot ID:
IPI00291624
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005654
Uniprot
OncoNet
Molecular Function:
GO:0003723
GO:0050733
GO:0000166
PhosphoSite+
KinaseNET
Biological Process:
GO:0000244
GO:0016482
GO:0048025
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
Y
T
R
P
P
N
T
S
L
F
I
R
N
V
A
Site 2
Y33
L
R
R
E
F
G
R
Y
G
P
I
V
D
V
Y
Site 3
Y40
Y
G
P
I
V
D
V
Y
I
P
L
D
F
Y
T
Site 4
Y46
V
Y
I
P
L
D
F
Y
T
R
R
P
R
G
F
Site 5
T47
Y
I
P
L
D
F
Y
T
R
R
P
R
G
F
A
Site 6
Y55
R
R
P
R
G
F
A
Y
V
Q
F
E
D
V
R
Site 7
Y69
R
D
A
E
D
A
L
Y
N
L
N
R
K
W
V
Site 8
T92
F
A
Q
G
D
R
K
T
P
G
Q
M
K
S
K
Site 9
S98
K
T
P
G
Q
M
K
S
K
E
R
H
P
C
S
Site 10
S105
S
K
E
R
H
P
C
S
P
S
D
H
R
R
S
Site 11
S107
E
R
H
P
C
S
P
S
D
H
R
R
S
R
S
Site 12
S112
S
P
S
D
H
R
R
S
R
S
P
S
Q
R
R
Site 13
S114
S
D
H
R
R
S
R
S
P
S
Q
R
R
T
R
Site 14
S116
H
R
R
S
R
S
P
S
Q
R
R
T
R
S
R
Site 15
T120
R
S
P
S
Q
R
R
T
R
S
R
S
S
S
W
Site 16
S122
P
S
Q
R
R
T
R
S
R
S
S
S
W
G
R
Site 17
S124
Q
R
R
T
R
S
R
S
S
S
W
G
R
N
R
Site 18
S125
R
R
T
R
S
R
S
S
S
W
G
R
N
R
R
Site 19
S126
R
T
R
S
R
S
S
S
W
G
R
N
R
R
R
Site 20
S134
W
G
R
N
R
R
R
S
D
S
L
K
E
S
R
Site 21
S136
R
N
R
R
R
S
D
S
L
K
E
S
R
H
R
Site 22
S140
R
S
D
S
L
K
E
S
R
H
R
R
F
S
Y
Site 23
S146
E
S
R
H
R
R
F
S
Y
S
Q
S
K
S
R
Site 24
Y147
S
R
H
R
R
F
S
Y
S
Q
S
K
S
R
S
Site 25
S148
R
H
R
R
F
S
Y
S
Q
S
K
S
R
S
K
Site 26
S150
R
R
F
S
Y
S
Q
S
K
S
R
S
K
S
L
Site 27
S152
F
S
Y
S
Q
S
K
S
R
S
K
S
L
P
R
Site 28
S154
Y
S
Q
S
K
S
R
S
K
S
L
P
R
R
S
Site 29
S156
Q
S
K
S
R
S
K
S
L
P
R
R
S
T
S
Site 30
S161
S
K
S
L
P
R
R
S
T
S
A
R
Q
S
R
Site 31
T162
K
S
L
P
R
R
S
T
S
A
R
Q
S
R
T
Site 32
S163
S
L
P
R
R
S
T
S
A
R
Q
S
R
T
P
Site 33
S167
R
S
T
S
A
R
Q
S
R
T
P
R
R
N
F
Site 34
T169
T
S
A
R
Q
S
R
T
P
R
R
N
F
G
S
Site 35
S176
T
P
R
R
N
F
G
S
R
G
R
S
R
S
K
Site 36
S180
N
F
G
S
R
G
R
S
R
S
K
S
L
Q
K
Site 37
S182
G
S
R
G
R
S
R
S
K
S
L
Q
K
R
S
Site 38
S184
R
G
R
S
R
S
K
S
L
Q
K
R
S
K
S
Site 39
S189
S
K
S
L
Q
K
R
S
K
S
I
G
K
S
Q
Site 40
S191
S
L
Q
K
R
S
K
S
I
G
K
S
Q
S
S
Site 41
S195
R
S
K
S
I
G
K
S
Q
S
S
S
P
Q
K
Site 42
S197
K
S
I
G
K
S
Q
S
S
S
P
Q
K
Q
T
Site 43
S199
I
G
K
S
Q
S
S
S
P
Q
K
Q
T
S
S
Site 44
T204
S
S
S
P
Q
K
Q
T
S
S
G
T
K
S
R
Site 45
S205
S
S
P
Q
K
Q
T
S
S
G
T
K
S
R
S
Site 46
S206
S
P
Q
K
Q
T
S
S
G
T
K
S
R
S
H
Site 47
T208
Q
K
Q
T
S
S
G
T
K
S
R
S
H
G
R
Site 48
S210
Q
T
S
S
G
T
K
S
R
S
H
G
R
H
S
Site 49
S212
S
S
G
T
K
S
R
S
H
G
R
H
S
D
S
Site 50
S217
S
R
S
H
G
R
H
S
D
S
I
A
R
S
P
Site 51
S219
S
H
G
R
H
S
D
S
I
A
R
S
P
C
K
Site 52
S223
H
S
D
S
I
A
R
S
P
C
K
S
P
K
G
Site 53
S227
I
A
R
S
P
C
K
S
P
K
G
Y
T
N
S
Site 54
Y231
P
C
K
S
P
K
G
Y
T
N
S
E
T
K
V
Site 55
S234
S
P
K
G
Y
T
N
S
E
T
K
V
Q
T
A
Site 56
S244
K
V
Q
T
A
K
H
S
H
F
R
S
H
S
R
Site 57
S248
A
K
H
S
H
F
R
S
H
S
R
S
R
S
Y
Site 58
S250
H
S
H
F
R
S
H
S
R
S
R
S
Y
R
H
Site 59
S252
H
F
R
S
H
S
R
S
R
S
Y
R
H
K
N
Site 60
S254
R
S
H
S
R
S
R
S
Y
R
H
K
N
S
W
Site 61
Y255
S
H
S
R
S
R
S
Y
R
H
K
N
S
W
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation