KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
CACNG8
Full Name:
Voltage-dependent calcium channel gamma-8 subunit
Alias:
CACNG6; Calcium channel, voltage-dependent, gamma subunit 8; CCG8; Neuronal voltage-gated calcium channel gamma-8
Type:
Ion channel, calcium
Mass (Da):
43481
Number AA:
425
UniProt ID:
Q8WXS5
International Prot ID:
IPI00103604
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030666
GO:0005891
Uniprot
OncoNet
Molecular Function:
GO:0005509
GO:0005245
PhosphoSite+
KinaseNET
Biological Process:
GO:0006816
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T65
T
A
G
G
D
D
G
T
P
H
R
G
G
G
G
Site 2
S74
H
R
G
G
G
G
A
S
E
K
K
D
P
G
G
Site 3
T83
K
K
D
P
G
G
L
T
H
S
G
L
W
R
I
Site 4
T111
I
N
H
F
P
E
D
T
D
Y
D
H
D
S
A
Site 5
Y113
H
F
P
E
D
T
D
Y
D
H
D
S
A
E
Y
Site 6
S117
D
T
D
Y
D
H
D
S
A
E
Y
L
L
R
V
Site 7
S149
G
G
V
C
V
A
A
S
R
V
Y
K
S
K
R
Site 8
Y152
C
V
A
A
S
R
V
Y
K
S
K
R
N
I
I
Site 9
S154
A
A
S
R
V
Y
K
S
K
R
N
I
I
L
G
Site 10
Y200
D
E
E
K
K
N
H
Y
S
Y
G
W
S
F
Y
Site 11
Y202
E
K
K
N
H
Y
S
Y
G
W
S
F
Y
F
G
Site 12
S238
S
R
E
A
H
C
Q
S
R
S
D
L
L
K
A
Site 13
S240
E
A
H
C
Q
S
R
S
D
L
L
K
A
G
G
Site 14
S252
A
G
G
G
A
G
G
S
G
G
S
G
P
S
A
Site 15
S255
G
A
G
G
S
G
G
S
G
P
S
A
I
L
R
Site 16
S258
G
S
G
G
S
G
P
S
A
I
L
R
L
P
S
Site 17
S265
S
A
I
L
R
L
P
S
Y
R
F
R
Y
R
R
Site 18
Y266
A
I
L
R
L
P
S
Y
R
F
R
Y
R
R
R
Site 19
Y270
L
P
S
Y
R
F
R
Y
R
R
R
S
R
S
S
Site 20
S274
R
F
R
Y
R
R
R
S
R
S
S
S
R
S
S
Site 21
S276
R
Y
R
R
R
S
R
S
S
S
R
S
S
E
P
Site 22
S277
Y
R
R
R
S
R
S
S
S
R
S
S
E
P
S
Site 23
S278
R
R
R
S
R
S
S
S
R
S
S
E
P
S
P
Site 24
S280
R
S
R
S
S
S
R
S
S
E
P
S
P
S
R
Site 25
S281
S
R
S
S
S
R
S
S
E
P
S
P
S
R
D
Site 26
S284
S
S
R
S
S
E
P
S
P
S
R
D
A
S
P
Site 27
S286
R
S
S
E
P
S
P
S
R
D
A
S
P
G
G
Site 28
S290
P
S
P
S
R
D
A
S
P
G
G
P
G
G
P
Site 29
S301
P
G
G
P
G
F
A
S
T
D
I
S
M
Y
T
Site 30
S305
G
F
A
S
T
D
I
S
M
Y
T
L
S
R
D
Site 31
Y307
A
S
T
D
I
S
M
Y
T
L
S
R
D
P
S
Site 32
T308
S
T
D
I
S
M
Y
T
L
S
R
D
P
S
K
Site 33
S310
D
I
S
M
Y
T
L
S
R
D
P
S
K
G
S
Site 34
S314
Y
T
L
S
R
D
P
S
K
G
S
V
A
A
G
Site 35
S317
S
R
D
P
S
K
G
S
V
A
A
G
L
A
G
Site 36
S362
A
E
R
D
R
G
G
S
S
G
F
L
T
L
H
Site 37
S363
E
R
D
R
G
G
S
S
G
F
L
T
L
H
N
Site 38
T367
G
G
S
S
G
F
L
T
L
H
N
A
F
P
K
Site 39
T381
K
E
A
G
G
G
V
T
V
T
V
T
R
P
P
Site 40
S399
A
P
R
H
P
A
P
S
A
P
A
P
G
T
L
Site 41
S413
L
A
K
G
A
A
A
S
N
T
N
T
L
N
R
Site 42
T417
A
A
A
S
N
T
N
T
L
N
R
K
T
T
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation