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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DYX1C1
Full Name:
Dyslexia susceptibility 1 candidate gene 1 protein
Alias:
Dyslexia susceptibility 1 candidate 1; DYXC1; EKN1; FLJ37882
Type:
Unknown function
Mass (Da):
48455
Number AA:
420
UniProt ID:
Q8WXU2
International Prot ID:
IPI00472826
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y8
M
P
L
Q
V
S
D
Y
S
W
Q
Q
T
K
T
Site 2
T13
S
D
Y
S
W
Q
Q
T
K
T
A
V
F
L
S
Site 3
T15
Y
S
W
Q
Q
T
K
T
A
V
F
L
S
L
P
Site 4
Y39
D
V
F
C
T
E
N
Y
L
K
V
N
F
P
P
Site 5
S61
Y
A
P
I
D
D
E
S
S
K
A
K
I
G
N
Site 6
S62
A
P
I
D
D
E
S
S
K
A
K
I
G
N
D
Site 7
T70
K
A
K
I
G
N
D
T
I
V
F
T
L
Y
K
Site 8
T85
K
E
A
A
M
W
E
T
L
S
V
T
G
V
D
Site 9
S87
A
A
M
W
E
T
L
S
V
T
G
V
D
K
E
Site 10
S103
M
Q
R
I
R
E
K
S
I
L
Q
A
Q
E
R
Site 11
Y128
A
K
R
E
D
Q
K
Y
A
L
S
V
M
M
K
Site 12
S131
E
D
Q
K
Y
A
L
S
V
M
M
K
I
E
E
Site 13
Y165
A
L
E
A
W
K
E
Y
Q
R
K
A
E
E
Q
Site 14
Y197
E
E
R
K
K
I
K
Y
K
S
L
T
R
N
L
Site 15
S199
R
K
K
I
K
Y
K
S
L
T
R
N
L
A
S
Site 16
S206
S
L
T
R
N
L
A
S
R
N
L
A
P
K
G
Site 17
S216
L
A
P
K
G
R
N
S
E
N
I
F
T
E
K
Site 18
T221
R
N
S
E
N
I
F
T
E
K
L
K
E
D
S
Site 19
S234
D
S
I
P
A
P
R
S
V
G
S
I
K
I
N
Site 20
S254
F
P
T
A
L
R
E
S
Q
V
A
E
E
E
E
Site 21
T275
E
A
R
R
A
M
N
T
D
I
A
E
L
C
D
Site 22
Y327
N
N
K
M
P
L
L
Y
L
N
R
A
A
C
H
Site 23
S348
H
K
A
I
E
D
S
S
K
A
L
E
L
L
M
Site 24
T359
E
L
L
M
P
P
V
T
D
N
A
N
A
R
M
Site 25
T374
K
A
H
V
R
R
G
T
A
F
C
Q
L
E
L
Site 26
Y389
Y
V
E
G
L
Q
D
Y
E
A
A
L
K
I
D
Site 27
S398
A
A
L
K
I
D
P
S
N
K
I
V
Q
I
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation