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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PIBF1
Full Name:
Progesterone-induced-blocking factor 1
Alias:
Type:
Mass (Da):
89805
Number AA:
757
UniProt ID:
Q8WXW3
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
S
R
K
I
S
K
E
S
K
K
V
N
Site 2
S15
E
S
K
K
V
N
I
S
S
S
L
E
S
E
D
Site 3
S17
K
K
V
N
I
S
S
S
L
E
S
E
D
I
S
Site 4
S20
N
I
S
S
S
L
E
S
E
D
I
S
L
E
T
Site 5
S24
S
L
E
S
E
D
I
S
L
E
T
T
V
P
T
Site 6
T28
E
D
I
S
L
E
T
T
V
P
T
D
D
I
S
Site 7
T31
S
L
E
T
T
V
P
T
D
D
I
S
S
S
E
Site 8
S35
T
V
P
T
D
D
I
S
S
S
E
E
R
E
G
Site 9
S36
V
P
T
D
D
I
S
S
S
E
E
R
E
G
K
Site 10
S37
P
T
D
D
I
S
S
S
E
E
R
E
G
K
V
Site 11
T47
R
E
G
K
V
R
I
T
R
Q
L
I
E
R
K
Site 12
S68
Q
L
L
K
I
E
L
S
Q
K
T
M
M
I
D
Site 13
Y81
I
D
N
L
K
V
D
Y
L
T
K
I
E
E
L
Site 14
T103
L
H
Q
K
Q
L
L
T
L
R
L
D
N
Q
L
Site 15
S118
A
F
Q
Q
K
D
A
S
K
Y
Q
E
L
M
K
Site 16
T162
N
L
R
D
F
E
L
T
E
E
Q
Y
I
K
L
Site 17
S178
A
F
P
E
D
Q
L
S
I
P
E
Y
V
S
V
Site 18
Y182
D
Q
L
S
I
P
E
Y
V
S
V
R
F
Y
E
Site 19
Y188
E
Y
V
S
V
R
F
Y
E
L
V
N
P
L
R
Site 20
S213
N
I
L
A
E
E
L
S
T
N
K
N
Q
L
K
Site 21
T214
I
L
A
E
E
L
S
T
N
K
N
Q
L
K
Q
Site 22
Y233
Y
E
E
D
R
K
N
Y
S
E
V
Q
I
R
C
Site 23
Y259
Q
L
I
Q
Q
G
D
Y
R
Q
E
N
Y
D
K
Site 24
Y264
G
D
Y
R
Q
E
N
Y
D
K
V
K
S
E
R
Site 25
S269
E
N
Y
D
K
V
K
S
E
R
D
A
L
E
Q
Site 26
T296
E
A
S
H
M
I
Q
T
K
E
R
S
E
L
S
Site 27
T314
V
T
L
E
Q
T
V
T
L
L
Q
K
D
K
E
Site 28
Y322
L
L
Q
K
D
K
E
Y
L
N
R
Q
N
M
E
Site 29
S331
N
R
Q
N
M
E
L
S
V
R
C
A
H
E
E
Site 30
Y362
R
E
E
M
Y
E
K
Y
V
A
S
R
D
H
Y
Site 31
Y369
Y
V
A
S
R
D
H
Y
K
T
E
Y
E
N
K
Site 32
T371
A
S
R
D
H
Y
K
T
E
Y
E
N
K
L
H
Site 33
Y373
R
D
H
Y
K
T
E
Y
E
N
K
L
H
D
E
Site 34
T388
L
E
Q
I
R
L
K
T
N
Q
E
I
D
Q
L
Site 35
S399
I
D
Q
L
R
N
A
S
R
E
M
Y
E
R
E
Site 36
Y403
R
N
A
S
R
E
M
Y
E
R
E
N
R
N
L
Site 37
Y442
H
D
Q
L
L
D
R
Y
R
E
L
Q
L
S
T
Site 38
S448
R
Y
R
E
L
Q
L
S
T
E
S
K
V
T
E
Site 39
T454
L
S
T
E
S
K
V
T
E
F
L
H
Q
S
K
Site 40
S460
V
T
E
F
L
H
Q
S
K
L
K
S
F
E
S
Site 41
S464
L
H
Q
S
K
L
K
S
F
E
S
E
R
V
Q
Site 42
S467
S
K
L
K
S
F
E
S
E
R
V
Q
L
L
Q
Site 43
T477
V
Q
L
L
Q
E
E
T
A
R
N
L
T
Q
C
Site 44
T482
E
E
T
A
R
N
L
T
Q
C
Q
L
E
C
E
Site 45
Y491
C
Q
L
E
C
E
K
Y
Q
K
K
L
E
V
L
Site 46
S504
V
L
T
K
E
F
Y
S
L
Q
A
S
S
E
K
Site 47
S508
E
F
Y
S
L
Q
A
S
S
E
K
R
I
T
E
Site 48
S509
F
Y
S
L
Q
A
S
S
E
K
R
I
T
E
L
Site 49
T514
A
S
S
E
K
R
I
T
E
L
Q
A
Q
N
S
Site 50
Y530
H
Q
A
R
L
D
I
Y
E
K
L
E
K
E
L
Site 51
Y560
A
E
R
V
L
F
S
Y
G
Y
G
A
N
V
P
Site 52
T569
Y
G
A
N
V
P
T
T
A
K
R
R
L
K
Q
Site 53
S577
A
K
R
R
L
K
Q
S
V
H
L
A
R
R
V
Site 54
S592
L
Q
L
E
K
Q
N
S
L
I
L
K
D
L
E
Site 55
T606
E
H
R
K
D
Q
V
T
Q
L
S
Q
E
L
D
Site 56
S609
K
D
Q
V
T
Q
L
S
Q
E
L
D
R
A
N
Site 57
S617
Q
E
L
D
R
A
N
S
L
L
N
Q
T
Q
Q
Site 58
T622
A
N
S
L
L
N
Q
T
Q
Q
P
Y
R
Y
L
Site 59
Y628
Q
T
Q
Q
P
Y
R
Y
L
I
E
S
V
R
Q
Site 60
S632
P
Y
R
Y
L
I
E
S
V
R
Q
R
D
S
K
Site 61
S638
E
S
V
R
Q
R
D
S
K
I
D
S
L
T
E
Site 62
S642
Q
R
D
S
K
I
D
S
L
T
E
S
I
A
Q
Site 63
T644
D
S
K
I
D
S
L
T
E
S
I
A
Q
L
E
Site 64
S646
K
I
D
S
L
T
E
S
I
A
Q
L
E
K
D
Site 65
S655
A
Q
L
E
K
D
V
S
N
L
N
K
E
K
S
Site 66
S662
S
N
L
N
K
E
K
S
A
L
L
Q
T
K
N
Site 67
S697
Q
I
L
V
K
M
H
S
K
H
S
E
N
S
L
Site 68
S700
V
K
M
H
S
K
H
S
E
N
S
L
L
L
T
Site 69
T707
S
E
N
S
L
L
L
T
K
T
E
P
K
H
V
Site 70
T709
N
S
L
L
L
T
K
T
E
P
K
H
V
T
E
Site 71
T722
T
E
N
Q
K
S
K
T
L
N
V
P
K
E
H
Site 72
T735
E
H
E
D
N
I
F
T
P
K
P
T
L
F
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation