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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ELYS
Full Name:
Protein ELYS
Alias:
AHCTF1; AHTF1; AT hook containing transcription factor 1; ELYS transcription factor like protein TMBS62; Embryonic large molecule derived from yolk sac; Transcription factor ELYS
Type:
Transcription protein
Mass (Da):
252498
Number AA:
2266
UniProt ID:
Q8WYP5
International Prot ID:
IPI00170594
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0000777
GO:0005737
GO:0016363
Uniprot
OncoNet
Molecular Function:
GO:0003677
PhosphoSite+
KinaseNET
Biological Process:
GO:0000910
GO:0007275
GO:0051292
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S10
D
L
R
A
Q
V
T
S
G
L
L
P
F
P
E
Site 2
T29
A
L
G
E
D
E
I
T
L
E
S
V
L
R
G
Site 3
S59
P
Q
L
E
V
V
N
S
I
T
G
E
R
L
S
Site 4
S66
S
I
T
G
E
R
L
S
A
Y
R
F
S
G
V
Site 5
Y68
T
G
E
R
L
S
A
Y
R
F
S
G
V
N
E
Site 6
S71
R
L
S
A
Y
R
F
S
G
V
N
E
Q
P
P
Site 7
S141
N
H
G
G
A
S
A
S
T
Q
H
L
H
P
S
Site 8
S148
S
T
Q
H
L
H
P
S
L
R
W
L
F
G
V
Site 9
S176
D
L
C
L
D
D
L
S
C
N
Q
N
E
V
E
Site 10
S185
N
Q
N
E
V
E
A
S
D
L
E
V
L
T
G
Site 11
S203
E
V
P
H
I
R
E
S
V
M
R
Q
G
R
H
Site 12
S224
S
P
T
G
T
A
V
S
T
L
S
Y
I
S
R
Site 13
T225
P
T
G
T
A
V
S
T
L
S
Y
I
S
R
T
Site 14
S227
G
T
A
V
S
T
L
S
Y
I
S
R
T
N
Q
Site 15
Y228
T
A
V
S
T
L
S
Y
I
S
R
T
N
Q
L
Site 16
Y256
M
K
S
M
K
R
E
Y
Y
I
Q
L
E
S
G
Site 17
Y257
K
S
M
K
R
E
Y
Y
I
Q
L
E
S
G
Q
Site 18
Y268
E
S
G
Q
V
P
V
Y
A
V
T
F
Q
E
P
Site 19
T271
Q
V
P
V
Y
A
V
T
F
Q
E
P
E
N
D
Site 20
S294
A
V
Q
S
T
Q
D
S
E
G
D
V
L
S
L
Site 21
S316
G
N
R
K
C
L
A
S
G
Q
I
L
Y
E
G
Site 22
Y326
I
L
Y
E
G
L
E
Y
C
E
E
R
Y
T
L
Site 23
T332
E
Y
C
E
E
R
Y
T
L
D
L
T
G
G
M
Site 24
T336
E
R
Y
T
L
D
L
T
G
G
M
F
P
L
R
Site 25
T346
M
F
P
L
R
G
Q
T
S
N
T
K
L
L
G
Site 26
S347
F
P
L
R
G
Q
T
S
N
T
K
L
L
G
C
Site 27
S356
T
K
L
L
G
C
Q
S
I
E
K
F
R
S
H
Site 28
S362
Q
S
I
E
K
F
R
S
H
G
D
R
E
E
G
Site 29
S375
E
G
V
N
E
A
L
S
P
D
T
S
V
S
V
Site 30
T378
N
E
A
L
S
P
D
T
S
V
S
V
F
T
W
Site 31
S379
E
A
L
S
P
D
T
S
V
S
V
F
T
W
Q
Site 32
S381
L
S
P
D
T
S
V
S
V
F
T
W
Q
V
N
Site 33
Y390
F
T
W
Q
V
N
I
Y
G
Q
G
K
P
S
V
Site 34
Y398
G
Q
G
K
P
S
V
Y
L
G
L
F
D
I
N
Site 35
S415
Y
H
A
Q
M
P
D
S
L
R
S
G
E
Y
L
Site 36
Y421
D
S
L
R
S
G
E
Y
L
H
N
C
S
Y
F
Site 37
Y427
E
Y
L
H
N
C
S
Y
F
A
L
W
S
L
E
Site 38
S438
W
S
L
E
S
V
V
S
R
T
S
P
H
G
I
Site 39
S441
E
S
V
V
S
R
T
S
P
H
G
I
L
D
I
Site 40
S454
D
I
L
V
H
E
R
S
L
N
R
G
V
P
P
Site 41
S462
L
N
R
G
V
P
P
S
Y
P
P
P
E
Q
F
Site 42
Y463
N
R
G
V
P
P
S
Y
P
P
P
E
Q
F
F
Site 43
T474
E
Q
F
F
N
P
S
T
Y
N
F
D
A
T
C
Site 44
T491
N
S
G
V
V
H
L
T
C
T
G
F
Q
K
E
Site 45
T501
G
F
Q
K
E
T
L
T
F
L
K
K
S
G
P
Site 46
Y518
N
E
L
I
P
D
G
Y
N
R
C
L
V
A
G
Site 47
S528
C
L
V
A
G
L
L
S
P
R
F
V
D
V
Q
Site 48
S537
C
L
V
A
G
L
L
S
P
R
F
V
D
V
Q
Site 49
S538
F
V
D
V
Q
P
S
S
L
S
Q
E
E
Q
L
Site 50
S540
D
V
Q
P
S
S
L
S
Q
E
E
Q
L
E
A
Site 51
T570
G
Y
I
R
R
W
I
T
E
E
Q
P
N
S
A
Site 52
S576
I
T
E
E
Q
P
N
S
A
T
N
L
R
F
V
Site 53
T646
A
S
E
A
R
E
I
T
E
R
G
L
I
D
L
Site 54
S654
E
R
G
L
I
D
L
S
N
K
F
V
V
S
H
Site 55
S686
L
P
E
G
I
D
D
S
V
Q
L
S
R
L
C
Site 56
Y694
V
Q
L
S
R
L
C
Y
N
Y
P
V
I
Q
N
Site 57
Y696
L
S
R
L
C
Y
N
Y
P
V
I
Q
N
Y
Y
Site 58
Y702
N
Y
P
V
I
Q
N
Y
Y
T
S
R
R
Q
K
Site 59
Y703
Y
P
V
I
Q
N
Y
Y
T
S
R
R
Q
K
F
Site 60
T704
P
V
I
Q
N
Y
Y
T
S
R
R
Q
K
F
E
Site 61
S714
R
Q
K
F
E
R
L
S
R
G
K
W
N
P
D
Site 62
T747
W
K
R
D
E
G
G
T
G
K
Y
P
P
A
S
Site 63
Y750
D
E
G
G
T
G
K
Y
P
P
A
S
L
H
A
Site 64
S754
T
G
K
Y
P
P
A
S
L
H
A
V
L
D
M
Site 65
Y785
Y
L
L
L
D
I
M
Y
S
F
P
N
K
T
D
Site 66
S786
L
L
L
D
I
M
Y
S
F
P
N
K
T
D
T
Site 67
T791
M
Y
S
F
P
N
K
T
D
T
P
I
E
S
F
Site 68
T793
S
F
P
N
K
T
D
T
P
I
E
S
F
P
T
Site 69
Y823
W
L
I
D
H
N
D
Y
E
S
G
L
D
L
L
Site 70
T835
D
L
L
F
H
P
A
T
A
K
P
L
S
W
Q
Site 71
S840
P
A
T
A
K
P
L
S
W
Q
H
S
K
I
I
Site 72
S852
K
I
I
Q
A
F
M
S
Q
G
E
H
R
Q
A
Site 73
Y862
E
H
R
Q
A
L
R
Y
I
Q
T
M
K
P
T
Site 74
T865
Q
A
L
R
Y
I
Q
T
M
K
P
T
V
S
S
Site 75
Y913
E
E
L
L
K
H
M
Y
E
V
C
Q
E
M
G
Site 76
T931
D
L
L
K
L
P
F
T
D
T
E
Q
E
C
L
Site 77
T933
L
K
L
P
F
T
D
T
E
Q
E
C
L
V
K
Site 78
S947
K
F
L
Q
S
S
A
S
V
Q
N
H
E
F
L
Site 79
Y964
H
H
L
Q
R
A
N
Y
V
P
A
L
K
L
N
Site 80
S990
D
P
R
L
R
E
R
S
L
A
R
N
S
I
L
Site 81
S995
E
R
S
L
A
R
N
S
I
L
D
Q
Y
G
K
Site 82
Y1000
R
N
S
I
L
D
Q
Y
G
K
I
L
P
R
V
Site 83
Y1019
A
I
E
R
A
K
P
Y
H
L
S
T
S
S
V
Site 84
S1022
R
A
K
P
Y
H
L
S
T
S
S
V
F
R
L
Site 85
S1024
K
P
Y
H
L
S
T
S
S
V
F
R
L
V
S
Site 86
S1025
P
Y
H
L
S
T
S
S
V
F
R
L
V
S
R
Site 87
S1031
S
S
V
F
R
L
V
S
R
P
K
P
L
S
A
Site 88
S1037
V
S
R
P
K
P
L
S
A
V
P
K
Q
V
V
Site 89
T1047
P
K
Q
V
V
T
G
T
V
L
T
R
S
V
F
Site 90
T1050
V
V
T
G
T
V
L
T
R
S
V
F
I
N
N
Site 91
S1068
K
I
G
E
V
W
A
S
K
E
P
I
N
S
T
Site 92
S1074
A
S
K
E
P
I
N
S
T
T
P
F
N
S
S
Site 93
T1075
S
K
E
P
I
N
S
T
T
P
F
N
S
S
K
Site 94
T1076
K
E
P
I
N
S
T
T
P
F
N
S
S
K
I
Site 95
S1080
N
S
T
T
P
F
N
S
S
K
I
E
E
P
S
Site 96
S1081
S
T
T
P
F
N
S
S
K
I
E
E
P
S
P
Site 97
S1087
S
S
K
I
E
E
P
S
P
I
V
Y
S
L
P
Site 98
Y1091
E
E
P
S
P
I
V
Y
S
L
P
A
P
E
L
Site 99
S1092
E
P
S
P
I
V
Y
S
L
P
A
P
E
L
P
Site 100
T1105
L
P
E
A
F
F
G
T
P
I
S
K
A
S
Q
Site 101
S1108
A
F
F
G
T
P
I
S
K
A
S
Q
K
I
S
Site 102
S1111
G
T
P
I
S
K
A
S
Q
K
I
S
R
L
L
Site 103
S1129
V
Q
P
V
P
R
P
S
Q
C
S
E
F
I
Q
Site 104
S1132
V
P
R
P
S
Q
C
S
E
F
I
Q
Q
S
S
Site 105
S1138
C
S
E
F
I
Q
Q
S
S
M
K
S
P
L
Y
Site 106
S1139
S
E
F
I
Q
Q
S
S
M
K
S
P
L
Y
L
Site 107
S1142
I
Q
Q
S
S
M
K
S
P
L
Y
L
V
S
R
Site 108
Y1145
S
S
M
K
S
P
L
Y
L
V
S
R
S
L
P
Site 109
S1148
K
S
P
L
Y
L
V
S
R
S
L
P
S
S
S
Site 110
S1150
P
L
Y
L
V
S
R
S
L
P
S
S
S
Q
L
Site 111
S1154
V
S
R
S
L
P
S
S
S
Q
L
K
G
S
P
Site 112
S1155
S
R
S
L
P
S
S
S
Q
L
K
G
S
P
Q
Site 113
S1160
S
S
S
Q
L
K
G
S
P
Q
A
I
S
R
A
Site 114
S1165
K
G
S
P
Q
A
I
S
R
A
S
E
L
H
L
Site 115
S1168
P
Q
A
I
S
R
A
S
E
L
H
L
L
E
T
Site 116
T1175
S
E
L
H
L
L
E
T
P
L
V
V
K
K
A
Site 117
S1188
K
A
K
S
L
A
M
S
V
T
T
S
G
F
S
Site 118
T1198
T
S
G
F
S
E
F
T
P
Q
S
I
L
R
S
Site 119
S1201
F
S
E
F
T
P
Q
S
I
L
R
S
T
L
R
Site 120
S1205
T
P
Q
S
I
L
R
S
T
L
R
S
T
P
L
Site 121
T1206
P
Q
S
I
L
R
S
T
L
R
S
T
P
L
A
Site 122
S1209
I
L
R
S
T
L
R
S
T
P
L
A
S
P
S
Site 123
T1210
L
R
S
T
L
R
S
T
P
L
A
S
P
S
P
Site 124
S1214
L
R
S
T
P
L
A
S
P
S
P
S
P
G
R
Site 125
S1216
S
T
P
L
A
S
P
S
P
S
P
G
R
S
P
Site 126
S1218
I
L
R
S
T
L
R
S
T
P
L
A
S
P
S
Site 127
S1222
P
S
P
S
P
G
R
S
P
Q
R
L
K
E
T
Site 128
T1229
S
P
Q
R
L
K
E
T
R
I
S
F
V
E
E
Site 129
S1232
R
L
K
E
T
R
I
S
F
V
E
E
D
V
H
Site 130
S1250
I
P
G
A
A
D
D
S
K
L
E
V
F
T
T
Site 131
T1256
D
S
K
L
E
V
F
T
T
P
K
K
C
A
V
Site 132
T1257
S
K
L
E
V
F
T
T
P
K
K
C
A
V
P
Site 133
S1272
V
E
T
E
W
L
K
S
K
D
R
T
T
S
F
Site 134
T1276
W
L
K
S
K
D
R
T
T
S
F
F
L
N
S
Site 135
T1277
L
K
S
K
D
R
T
T
S
F
F
L
N
S
P
Site 136
S1278
K
S
K
D
R
T
T
S
F
F
L
N
S
P
E
Site 137
S1283
T
T
S
F
F
L
N
S
P
E
K
E
H
Q
E
Site 138
S1295
H
Q
E
M
D
E
G
S
Q
S
L
E
K
L
D
Site 139
S1297
E
M
D
E
G
S
Q
S
L
E
K
L
D
V
S
Site 140
S1304
H
Q
E
M
D
E
G
S
Q
S
L
E
K
L
D
Site 141
S1308
L
D
V
S
K
G
N
S
S
V
S
I
T
S
D
Site 142
S1309
D
V
S
K
G
N
S
S
V
S
I
T
S
D
E
Site 143
S1311
S
K
G
N
S
S
V
S
I
T
S
D
E
T
T
Site 144
T1313
G
N
S
S
V
S
I
T
S
D
E
T
T
L
E
Site 145
S1314
N
S
S
V
S
I
T
S
D
E
T
T
L
E
Y
Site 146
T1318
S
I
T
S
D
E
T
T
L
E
Y
Q
D
A
P
Site 147
Y1321
S
D
E
T
T
L
E
Y
Q
D
A
P
S
P
E
Site 148
S1326
L
E
Y
Q
D
A
P
S
P
E
D
L
E
E
T
Site 149
T1333
S
P
E
D
L
E
E
T
V
F
T
A
S
K
P
Site 150
T1336
D
L
E
E
T
V
F
T
A
S
K
P
K
S
S
Site 151
S1338
E
E
T
V
F
T
A
S
K
P
K
S
S
S
T
Site 152
S1342
F
T
A
S
K
P
K
S
S
S
T
A
L
T
T
Site 153
S1344
A
S
K
P
K
S
S
S
T
A
L
T
T
N
V
Site 154
T1348
K
S
S
S
T
A
L
T
T
N
V
T
E
Q
T
Site 155
S1366
G
D
K
D
V
F
A
S
E
V
T
P
S
D
L
Site 156
T1369
D
V
F
A
S
E
V
T
P
S
D
L
Q
K
Q
Site 157
S1371
F
A
S
E
V
T
P
S
D
L
Q
K
Q
M
G
Site 158
T1385
G
N
L
E
D
A
E
T
K
D
L
L
V
A
A
Site 159
S1402
F
S
E
L
N
H
L
S
P
V
Q
G
T
E
A
Site 160
S1426
G
K
I
F
T
Q
K
S
K
V
P
V
L
D
E
Site 161
S1437
V
L
D
E
G
L
T
S
V
E
T
Y
T
P
A
Site 162
T1440
E
G
L
T
S
V
E
T
Y
T
P
A
I
R
A
Site 163
Y1441
G
L
T
S
V
E
T
Y
T
P
A
I
R
A
N
Site 164
T1442
L
T
S
V
E
T
Y
T
P
A
I
R
A
N
D
Site 165
S1452
I
R
A
N
D
N
K
S
M
A
D
V
L
G
D
Site 166
S1464
L
G
D
G
G
N
S
S
L
T
I
S
E
G
P
Site 167
T1466
D
G
G
N
S
S
L
T
I
S
E
G
P
I
V
Site 168
S1468
G
N
S
S
L
T
I
S
E
G
P
I
V
S
E
Site 169
S1474
I
S
E
G
P
I
V
S
E
R
R
L
N
Q
E
Site 170
S1500
E
V
G
V
L
K
E
S
V
D
L
P
E
E
K
Site 171
S1511
P
E
E
K
L
P
I
S
D
S
P
P
D
T
Q
Site 172
S1513
E
K
L
P
I
S
D
S
P
P
D
T
Q
E
I
Site 173
T1517
I
S
D
S
P
P
D
T
Q
E
I
H
V
I
E
Site 174
S1533
E
K
L
E
A
Q
D
S
G
E
E
A
R
N
L
Site 175
S1541
G
E
E
A
R
N
L
S
F
N
E
L
Y
P
S
Site 176
Y1546
N
L
S
F
N
E
L
Y
P
S
G
T
L
K
L
Site 177
S1548
S
F
N
E
L
Y
P
S
G
T
L
K
L
Q
Y
Site 178
Y1555
S
G
T
L
K
L
Q
Y
N
F
D
T
I
D
Q
Site 179
S1610
V
E
P
G
D
F
A
S
S
D
V
L
P
K
A
Site 180
S1647
N
L
P
S
A
V
T
S
D
Q
K
S
Q
K
V
Site 181
S1651
A
V
T
S
D
Q
K
S
Q
K
V
D
T
L
P
Site 182
T1656
Q
K
S
Q
K
V
D
T
L
P
Y
V
P
E
P
Site 183
Y1659
Q
K
V
D
T
L
P
Y
V
P
E
P
I
K
V
Site 184
T1679
L
L
D
V
I
K
D
T
R
S
K
E
I
T
S
Site 185
S1681
D
V
I
K
D
T
R
S
K
E
I
T
S
D
T
Site 186
T1685
D
T
R
S
K
E
I
T
S
D
T
M
E
Q
S
Site 187
S1686
T
R
S
K
E
I
T
S
D
T
M
E
Q
S
I
Site 188
T1688
S
K
E
I
T
S
D
T
M
E
Q
S
I
H
E
Site 189
S1692
T
S
D
T
M
E
Q
S
I
H
E
T
I
P
L
Site 190
T1696
M
E
Q
S
I
H
E
T
I
P
L
V
S
Q
N
Site 191
S1713
C
P
T
K
L
V
K
S
A
F
K
T
A
Q
E
Site 192
T1717
L
V
K
S
A
F
K
T
A
Q
E
T
S
T
M
Site 193
S1729
S
T
M
T
M
N
V
S
Q
V
D
D
V
V
S
Site 194
S1753
I
Q
N
V
N
V
K
S
A
Q
Q
E
A
S
A
Site 195
T1764
E
A
S
A
D
V
A
T
P
K
M
P
G
Q
S
Site 196
S1771
T
P
K
M
P
G
Q
S
V
R
K
K
T
R
K
Site 197
T1776
G
Q
S
V
R
K
K
T
R
K
A
K
E
I
S
Site 198
S1786
A
K
E
I
S
E
A
S
E
N
I
Y
S
D
V
Site 199
Y1790
S
E
A
S
E
N
I
Y
S
D
V
R
G
L
S
Site 200
S1791
E
A
S
E
N
I
Y
S
D
V
R
G
L
S
Q
Site 201
S1797
Y
S
D
V
R
G
L
S
Q
N
Q
Q
I
P
Q
Site 202
S1806
Y
S
D
V
R
G
L
S
Q
N
Q
Q
I
P
Q
Site 203
T1808
Q
I
P
Q
N
S
V
T
P
R
R
G
R
R
K
Site 204
S1828
D
I
L
E
N
T
S
S
V
E
Q
E
L
Q
I
Site 205
T1836
V
E
Q
E
L
Q
I
T
T
G
R
E
S
K
R
Site 206
T1837
E
Q
E
L
Q
I
T
T
G
R
E
S
K
R
L
Site 207
S1841
Q
I
T
T
G
R
E
S
K
R
L
K
S
S
Q
Site 208
S1846
R
E
S
K
R
L
K
S
S
Q
L
L
E
P
A
Site 209
S1847
E
S
K
R
L
K
S
S
Q
L
L
E
P
A
V
Site 210
S1866
K
K
E
V
K
V
S
S
V
T
K
R
T
P
R
Site 211
T1871
V
S
S
V
T
K
R
T
P
R
R
I
K
R
S
Site 212
S1878
T
P
R
R
I
K
R
S
V
E
N
Q
E
S
V
Site 213
S1884
R
S
V
E
N
Q
E
S
V
E
I
I
N
D
L
Site 214
S1894
I
I
N
D
L
K
V
S
T
V
T
S
P
S
R
Site 215
T1895
I
N
D
L
K
V
S
T
V
T
S
P
S
R
M
Site 216
T1897
D
L
K
V
S
T
V
T
S
P
S
R
M
I
R
Site 217
S1898
L
K
V
S
T
V
T
S
P
S
R
M
I
R
K
Site 218
S1900
V
S
T
V
T
S
P
S
R
M
I
R
K
L
R
Site 219
T1909
M
I
R
K
L
R
S
T
N
L
D
A
S
E
N
Site 220
S1914
R
S
T
N
L
D
A
S
E
N
T
G
N
K
Q
Site 221
S1925
G
N
K
Q
D
D
K
S
S
D
K
Q
L
R
I
Site 222
S1926
N
K
Q
D
D
K
S
S
D
K
Q
L
R
I
K
Site 223
S1944
R
V
R
G
R
E
V
S
P
S
D
V
R
E
D
Site 224
S1946
R
G
R
E
V
S
P
S
D
V
R
E
D
S
N
Site 225
S1952
P
S
D
V
R
E
D
S
N
L
E
S
S
Q
L
Site 226
S1956
R
E
D
S
N
L
E
S
S
Q
L
T
V
Q
A
Site 227
T1960
N
L
E
S
S
Q
L
T
V
Q
A
E
F
D
M
Site 228
S1968
V
Q
A
E
F
D
M
S
A
I
P
R
K
R
G
Site 229
S1983
R
P
R
K
I
N
P
S
E
D
V
G
S
K
A
Site 230
S1988
N
P
S
E
D
V
G
S
K
A
V
K
E
E
R
Site 231
S1996
K
A
V
K
E
E
R
S
P
K
K
K
E
A
P
Site 232
S2004
P
K
K
K
E
A
P
S
I
R
R
R
S
T
R
Site 233
S2009
A
P
S
I
R
R
R
S
T
R
N
T
P
A
K
Site 234
T2010
P
S
I
R
R
R
S
T
R
N
T
P
A
K
S
Site 235
T2013
R
R
R
S
T
R
N
T
P
A
K
S
E
N
V
Site 236
S2017
T
R
N
T
P
A
K
S
E
N
V
D
V
G
K
Site 237
S2030
G
K
P
A
L
G
K
S
I
L
V
P
N
E
E
Site 238
S2039
L
V
P
N
E
E
L
S
M
V
M
S
S
K
K
Site 239
S2043
E
E
L
S
M
V
M
S
S
K
K
K
L
T
K
Site 240
S2044
E
L
S
M
V
M
S
S
K
K
K
L
T
K
K
Site 241
T2052
K
K
K
L
T
K
K
T
E
S
Q
S
Q
K
R
Site 242
S2054
K
L
T
K
K
T
E
S
Q
S
Q
K
R
S
L
Site 243
S2056
T
K
K
T
E
S
Q
S
Q
K
R
S
L
H
S
Site 244
S2060
E
S
Q
S
Q
K
R
S
L
H
S
V
S
E
E
Site 245
S2063
S
Q
K
R
S
L
H
S
V
S
E
E
R
T
D
Site 246
S2065
K
R
S
L
H
S
V
S
E
E
R
T
D
E
M
Site 247
T2069
H
S
V
S
E
E
R
T
D
E
M
T
H
K
E
Site 248
T2073
E
E
R
T
D
E
M
T
H
K
E
T
N
E
Q
Site 249
T2087
Q
E
E
R
L
L
A
T
A
S
F
T
K
S
S
Site 250
S2089
E
R
L
L
A
T
A
S
F
T
K
S
S
R
S
Site 251
T2091
L
L
A
T
A
S
F
T
K
S
S
R
S
S
R
Site 252
S2093
A
T
A
S
F
T
K
S
S
R
S
S
R
T
R
Site 253
S2094
T
A
S
F
T
K
S
S
R
S
S
R
T
R
S
Site 254
S2096
S
F
T
K
S
S
R
S
S
R
T
R
S
S
K
Site 255
S2097
F
T
K
S
S
R
S
S
R
T
R
S
S
K
A
Site 256
S2101
S
R
S
S
R
T
R
S
S
K
A
I
L
L
P
Site 257
S2102
R
S
S
R
T
R
S
S
K
A
I
L
L
P
D
Site 258
S2111
A
I
L
L
P
D
L
S
E
P
N
N
E
P
L
Site 259
S2120
P
N
N
E
P
L
F
S
P
A
S
E
V
P
R
Site 260
S2123
E
P
L
F
S
P
A
S
E
V
P
R
K
A
K
Site 261
S2154
L
S
S
Q
F
V
I
S
P
P
A
L
R
S
R
Site 262
S2160
I
S
P
P
A
L
R
S
R
Q
K
N
T
S
N
Site 263
S2166
R
S
R
Q
K
N
T
S
N
K
N
K
L
E
D
Site 264
S2181
E
L
K
D
D
A
Q
S
V
E
T
L
G
K
P
Site 265
T2195
P
K
A
K
R
I
R
T
S
K
T
K
Q
A
S
Site 266
S2196
K
A
K
R
I
R
T
S
K
T
K
Q
A
S
K
Site 267
T2198
K
R
I
R
T
S
K
T
K
Q
A
S
K
N
T
Site 268
S2209
S
K
N
T
E
K
E
S
A
W
S
P
P
P
I
Site 269
S2212
T
E
K
E
S
A
W
S
P
P
P
I
E
I
R
Site 270
S2222
P
I
E
I
R
L
I
S
P
L
A
S
P
A
D
Site 271
S2226
R
L
I
S
P
L
A
S
P
A
D
G
V
K
S
Site 272
S2233
S
P
A
D
G
V
K
S
K
P
R
K
T
T
E
Site 273
T2238
V
K
S
K
P
R
K
T
T
E
V
T
G
T
G
Site 274
T2239
K
S
K
P
R
K
T
T
E
V
T
G
T
G
L
Site 275
T2242
P
R
K
T
T
E
V
T
G
T
G
L
G
R
N
Site 276
T2244
K
T
T
E
V
T
G
T
G
L
G
R
N
R
K
Site 277
S2254
G
R
N
R
K
K
L
S
S
Y
P
K
Q
I
L
Site 278
S2255
R
N
R
K
K
L
S
S
Y
P
K
Q
I
L
R
Site 279
Y2256
N
R
K
K
L
S
S
Y
P
K
Q
I
L
R
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation