PhosphoNET

           
Protein Info 
   
Short Name:  DDB2
Full Name:  DNA damage-binding protein 2
Alias:  damage-specific DNA binding 2 (48kD); damage-specific DNA binding 2, 48kDa; damage-specific DNA binding protein 2; damage-specific DNA binding protein 2, 48kDa; damage-specific DNA-binding 2; DDB p48; DDB p48 subunit; DDBb; DNA damage-binding 2; FLJ34321; UV-damaged DNA-binding 2; UV-damaged DNA-binding protein 2; UV-DDB 2; UV-DDB2; xeroderma pigmentosum group E; xeroderma pigmentosum group E protein
Type:  DNA repair
Mass (Da):  47864
Number AA:  427
UniProt ID:  Q92466
International Prot ID:  IPI00021518
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005654  GO:0043234  GO:0032991 Uniprot OncoNet
Molecular Function:  GO:0003684  GO:0005515  GO:0003684 PhosphoSite+ KinaseNET
Biological Process:  GO:0019941  GO:0000718  GO:0051865 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T9APKKRPETQKTSEIV
Site 2T12KRPETQKTSEIVLRP
Site 3S24LRPRNKRSRSPLELE
Site 4S26PRNKRSRSPLELEPE
Site 5S42KKLCAKGSGPSRRCD
Site 6S45CAKGSGPSRRCDSDC
Site 7S50GPSRRCDSDCLWVGL
Site 8S68QILPPCRSIVRTLHQ
Site 9T72PCRSIVRTLHQHKLG
Site 10S82QHKLGRASWPSVQQG
Site 11S85LGRASWPSVQQGLQQ
Site 12S93VQQGLQQSFLHTLDS
Site 13T97LQQSFLHTLDSYRIL
Site 14S100SFLHTLDSYRILQKA
Site 15Y101FLHTLDSYRILQKAA
Site 16T115APFDRRATSLAWHPT
Site 17S116PFDRRATSLAWHPTH
Site 18T122TSLAWHPTHPSTVAV
Site 19T126WHPTHPSTVAVGSKG
Site 20S131PSTVAVGSKGGDIML
Site 21Y173PLNTNQFYASSMEGT
Site 22S176TNQFYASSMEGTTRL
Site 23T180YASSMEGTTRLQDFK
Site 24T266ATASVDQTVKIWDLR
Site 25S280RQVRGKASFLYSLPH
Site 26Y283RGKASFLYSLPHRHP
Site 27S284GKASFLYSLPHRHPV
Site 28T305PDGARLLTTDQKSEI
Site 29T306DGARLLTTDQKSEIR
Site 30S310LLTTDQKSEIRVYSA
Site 31Y315QKSEIRVYSASQWDC
Site 32S316KSEIRVYSASQWDCP
Site 33S318EIRVYSASQWDCPLG
Site 34Y348KAAWHPRYNLIVVGR
Site 35Y356NLIVVGRYPDPNFKS
Site 36S363YPDPNFKSCTPYELR
Site 37T365DPNFKSCTPYELRTI
Site 38Y367NFKSCTPYELRTIDV
Site 39Y387GKMMCQLYDPESSGI
Site 40S391CQLYDPESSGISSLN
Site 41S392QLYDPESSGISSLNE
Site 42S395DPESSGISSLNEFNP
Site 43S396PESSGISSLNEFNPM
Site 44T406EFNPMGDTLASAMGY
Site 45S419GYHILIWSQEEARTR
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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