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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TFAP2B
Full Name:
Transcription factor AP-2-beta
Alias:
Activating enhancer-binding protein 2 beta; AP2B; AP-2B; AP2-B; AP2-beta
Type:
Nucleus protein
Mass (Da):
50474
Number AA:
460
UniProt ID:
Q92481
International Prot ID:
IPI00216446
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0043226
GO:0043227
Uniprot
OncoNet
Molecular Function:
GO:0003676
GO:0003677
GO:0003700
PhosphoSite+
KinaseNET
Biological Process:
GO:0001822
GO:0006139
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y22
K
L
V
E
N
V
K
Y
E
D
I
Y
E
D
R
Site 2
Y26
N
V
K
Y
E
D
I
Y
E
D
R
H
D
G
V
Site 3
S35
D
R
H
D
G
V
P
S
H
S
S
R
L
S
Q
Site 4
S37
H
D
G
V
P
S
H
S
S
R
L
S
Q
L
G
Site 5
S38
D
G
V
P
S
H
S
S
R
L
S
Q
L
G
S
Site 6
S41
P
S
H
S
S
R
L
S
Q
L
G
S
V
S
Q
Site 7
S45
S
R
L
S
Q
L
G
S
V
S
Q
G
P
Y
S
Site 8
S47
L
S
Q
L
G
S
V
S
Q
G
P
Y
S
S
A
Site 9
Y51
G
S
V
S
Q
G
P
Y
S
S
A
P
P
L
S
Site 10
S52
S
V
S
Q
G
P
Y
S
S
A
P
P
L
S
H
Site 11
S53
V
S
Q
G
P
Y
S
S
A
P
P
L
S
H
T
Site 12
S58
Y
S
S
A
P
P
L
S
H
T
P
S
S
D
F
Site 13
T60
S
A
P
P
L
S
H
T
P
S
S
D
F
Q
P
Site 14
S62
P
P
L
S
H
T
P
S
S
D
F
Q
P
P
Y
Site 15
S63
P
L
S
H
T
P
S
S
D
F
Q
P
P
Y
F
Site 16
Y69
S
S
D
F
Q
P
P
Y
F
P
P
P
Y
Q
P
Site 17
Y74
P
P
Y
F
P
P
P
Y
Q
P
L
P
Y
H
Q
Site 18
Y79
P
P
Y
Q
P
L
P
Y
H
Q
S
Q
D
P
Y
Site 19
S82
Q
P
L
P
Y
H
Q
S
Q
D
P
Y
S
H
V
Site 20
Y86
Y
H
Q
S
Q
D
P
Y
S
H
V
N
D
P
Y
Site 21
S87
H
Q
S
Q
D
P
Y
S
H
V
N
D
P
Y
S
Site 22
Y93
Y
S
H
V
N
D
P
Y
S
L
N
P
L
H
Q
Site 23
S94
S
H
V
N
D
P
Y
S
L
N
P
L
H
Q
P
Site 24
S116
R
Q
R
Q
E
V
G
S
E
A
G
S
L
L
P
Site 25
S120
E
V
G
S
E
A
G
S
L
L
P
Q
P
R
A
Site 26
S133
R
A
A
L
P
Q
L
S
G
L
D
P
R
R
D
Site 27
Y141
G
L
D
P
R
R
D
Y
H
S
V
R
R
P
D
Site 28
S143
D
P
R
R
D
Y
H
S
V
R
R
P
D
V
L
Site 29
S153
R
P
D
V
L
L
H
S
A
H
H
G
L
D
A
Site 30
S167
A
G
M
G
D
S
L
S
L
H
G
L
G
H
P
Site 31
S181
P
G
M
E
D
V
Q
S
V
E
D
A
N
N
S
Site 32
S207
K
V
P
V
P
P
K
S
V
T
S
L
M
M
N
Site 33
S210
V
P
P
K
S
V
T
S
L
M
M
N
K
D
G
Site 34
S223
D
G
F
L
G
G
M
S
V
N
T
G
E
V
F
Site 35
S238
C
S
V
P
G
R
L
S
L
L
S
S
T
S
K
Site 36
S241
P
G
R
L
S
L
L
S
S
T
S
K
Y
K
V
Site 37
S242
G
R
L
S
L
L
S
S
T
S
K
Y
K
V
T
Site 38
S244
L
S
L
L
S
S
T
S
K
Y
K
V
T
V
G
Site 39
Y246
L
L
S
S
T
S
K
Y
K
V
T
V
G
E
V
Site 40
T249
S
T
S
K
Y
K
V
T
V
G
E
V
Q
R
R
Site 41
S258
G
E
V
Q
R
R
L
S
P
P
E
C
L
N
A
Site 42
S277
G
V
L
R
R
A
K
S
K
N
G
G
R
S
L
Site 43
S283
K
S
K
N
G
G
R
S
L
R
E
R
L
E
K
Site 44
T306
R
R
K
A
A
N
V
T
L
L
T
S
L
V
E
Site 45
Y325
H
L
A
R
D
F
G
Y
I
C
E
T
E
F
P
Site 46
Y339
P
A
K
A
V
S
E
Y
L
N
R
Q
H
T
D
Site 47
T345
E
Y
L
N
R
Q
H
T
D
P
S
D
L
H
S
Site 48
S348
N
R
Q
H
T
D
P
S
D
L
H
S
R
K
N
Site 49
S352
T
D
P
S
D
L
H
S
R
K
N
M
L
L
A
Site 50
T376
D
L
L
A
Q
D
R
T
P
I
G
N
S
R
P
Site 51
S384
P
I
G
N
S
R
P
S
P
I
L
E
P
G
I
Site 52
T422
T
A
L
Q
N
Y
L
T
E
A
L
K
G
M
D
Site 53
T438
M
F
L
N
N
T
T
T
N
R
H
T
S
G
E
Site 54
T442
N
T
T
T
N
R
H
T
S
G
E
G
P
G
S
Site 55
S443
T
T
T
N
R
H
T
S
G
E
G
P
G
S
K
Site 56
S449
T
S
G
E
G
P
G
S
K
T
G
D
K
E
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation