PhosphoNET

           
Protein Info 
   
Short Name:  SHC3
Full Name:  SHC-transforming protein 3
Alias:  Neuronal Shc; NSHC; N-Shc; Protein Rai; SH2 domain protein C3; SHC (Srcy 2 domain containing) transforming protein 3; SHC transforming protein 3; SHCC; Src homology 2 domain containing transforming protein C3
Type:  Adapter/scaffold protein
Mass (Da):  64056
Number AA:  594
UniProt ID:  Q92529
International Prot ID:  IPI00409679
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:  GO:0005515  GO:0004871   PhosphoSite+ KinaseNET
Biological Process:  GO:0007265  GO:0007417  GO:0007173 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1Y7_MLPRTKYNRFRNDS
Site 2S14YNRFRNDSVTSVDDL
Site 3T16RFRNDSVTSVDDLLH
Site 4S17FRNDSVTSVDDLLHS
Site 5S26DDLLHSLSVSGGGGK
Site 6S35SGGGGKVSAARATPA
Site 7S63APDDGPGSLGHLLHK
Site 8S72GHLLHKVSHLKLSSS
Site 9S77KVSHLKLSSSGLRGL
Site 10S79SHLKLSSSGLRGLSS
Site 11S85SSGLRGLSSAARERA
Site 12S86SGLRGLSSAARERAG
Site 13S97ERAGARLSGSCSAPS
Site 14S104SGSCSAPSLAAPDGS
Site 15S111SLAAPDGSAPSAPRA
Site 16S114APDGSAPSAPRAPAM
Site 17S122APRAPAMSAARKGRP
Site 18S145PRGAPHASDQVLGPG
Site 19S171EVLRSMRSLDFSTRT
Site 20S175SMRSLDFSTRTQITR
Site 21S206FKKRKPPSKMLSSIL
Site 22S210KPPSKMLSSILGKSN
Site 23S211PPSKMLSSILGKSNL
Site 24S224NLQFAGMSISLTIST
Site 25S233SLTISTASLNLRTPD
Site 26T238TASLNLRTPDSKQII
Site 27S241LNLRTPDSKQIIANH
Site 28S252IANHHMRSISFASGG
Site 29S254NHHMRSISFASGGDP
Site 30S257MRSISFASGGDPDTT
Site 31T263ASGGDPDTTDYVAYV
Site 32T264SGGDPDTTDYVAYVA
Site 33Y266GDPDTTDYVAYVAKD
Site 34Y269DTTDYVAYVAKDPVN
Site 35Y308FELRFKQYLQCPTKI
Site 36T313KQYLQCPTKIPALHD
Site 37S324ALHDRMQSLDEPWTE
Site 38T330QSLDEPWTEEEGDGS
Site 39S337TEEEGDGSDHPYYNS
Site 40Y341GDGSDHPYYNSIPSK
Site 41Y342DGSDHPYYNSIPSKM
Site 42S344SDHPYYNSIPSKMPP
Site 43S347PYYNSIPSKMPPPGG
Site 44T369PRPHAPDTAQFAGKE
Site 45Y379FAGKEQTYYQGRHLG
Site 46Y380AGKEQTYYQGRHLGD
Site 47T396FGEDWQQTPLRQGSS
Site 48S402QTPLRQGSSDIYSTP
Site 49S403TPLRQGSSDIYSTPE
Site 50Y406RQGSSDIYSTPEGKL
Site 51S407QGSSDIYSTPEGKLH
Site 52T408GSSDIYSTPEGKLHV
Site 53Y424PTGEAPTYVNTQQIP
Site 54S440QAWPAAVSSAESSPR
Site 55S441AWPAAVSSAESSPRK
Site 56S444AAVSSAESSPRKDLF
Site 57S445AVSSAESSPRKDLFD
Site 58S474PVLSKAASVECISPV
Site 59S479AASVECISPVSPRAP
Site 60S482VECISPVSPRAPDAK
Site 61S524GDFLVRKSTTNPGSF
Site 62T525DFLVRKSTTNPGSFV
Site 63S530KSTTNPGSFVLTGMH
Site 64T534NPGSFVLTGMHNGQA
Site 65S562TKDRVFDSISHLINH
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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