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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SNX19
Full Name:
Sorting nexin-19
Alias:
Type:
Mass (Da):
108598
Number AA:
992
UniProt ID:
Q92543
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T12
T
V
P
P
F
Q
E
T
P
A
G
S
S
C
H
Site 2
S74
S
S
L
A
G
V
A
S
G
R
L
H
L
E
R
Site 3
T105
L
E
R
E
I
N
R
T
I
Q
M
I
I
R
D
Site 4
Y118
R
D
F
V
L
S
W
Y
R
S
V
S
Q
E
P
Site 5
S120
F
V
L
S
W
Y
R
S
V
S
Q
E
P
A
F
Site 6
S122
L
S
W
Y
R
S
V
S
Q
E
P
A
F
E
E
Site 7
S147
Q
E
L
R
R
R
M
S
V
M
D
S
H
A
V
Site 8
S151
R
R
M
S
V
M
D
S
H
A
V
A
Q
S
V
Site 9
Y169
C
G
C
H
L
Q
S
Y
I
Q
A
K
E
A
T
Site 10
Y192
P
S
H
L
W
E
A
Y
C
R
A
T
A
P
H
Site 11
S204
A
P
H
P
A
V
H
S
P
S
A
E
V
T
Y
Site 12
T210
H
S
P
S
A
E
V
T
Y
T
R
G
V
V
N
Site 13
Y211
S
P
S
A
E
V
T
Y
T
R
G
V
V
N
L
Site 14
S280
D
P
A
P
C
P
A
S
A
P
E
Q
P
S
V
Site 15
S286
A
S
A
P
E
Q
P
S
V
P
T
S
L
P
L
Site 16
Y316
A
A
P
V
F
L
S
Y
S
E
P
E
G
S
A
Site 17
S317
A
P
V
F
L
S
Y
S
E
P
E
G
S
A
G
Site 18
S322
S
Y
S
E
P
E
G
S
A
G
P
S
P
E
V
Site 19
S326
P
E
G
S
A
G
P
S
P
E
V
E
E
G
H
Site 20
S353
E
R
K
V
G
N
N
S
S
H
F
L
Q
P
N
Site 21
S354
R
K
V
G
N
N
S
S
H
F
L
Q
P
N
L
Site 22
S371
P
L
F
L
C
E
D
S
E
L
E
S
P
L
S
Site 23
S375
C
E
D
S
E
L
E
S
P
L
S
E
L
G
K
Site 24
S378
S
E
L
E
S
P
L
S
E
L
G
K
E
T
I
Site 25
S395
M
T
P
G
S
F
L
S
D
R
I
Q
D
A
L
Site 26
S408
A
L
C
A
L
E
S
S
Q
A
L
E
P
K
D
Site 27
T430
E
A
E
E
G
P
G
T
E
T
E
T
G
L
P
Site 28
T434
G
P
G
T
E
T
E
T
G
L
P
V
S
T
L
Site 29
S439
T
E
T
G
L
P
V
S
T
L
N
S
C
P
E
Site 30
T440
E
T
G
L
P
V
S
T
L
N
S
C
P
E
I
Site 31
T475
L
L
E
G
P
E
K
T
C
P
S
R
P
S
C
Site 32
S478
G
P
E
K
T
C
P
S
R
P
S
C
L
E
K
Site 33
S481
K
T
C
P
S
R
P
S
C
L
E
K
D
L
T
Site 34
T488
S
C
L
E
K
D
L
T
N
D
V
S
S
L
D
Site 35
S492
K
D
L
T
N
D
V
S
S
L
D
P
T
L
P
Site 36
S493
D
L
T
N
D
V
S
S
L
D
P
T
L
P
P
Site 37
S506
P
P
V
L
L
S
S
S
P
P
G
P
L
S
S
Site 38
S512
S
S
P
P
G
P
L
S
S
A
T
F
S
F
E
Site 39
S513
S
P
P
G
P
L
S
S
A
T
F
S
F
E
P
Site 40
T515
P
G
P
L
S
S
A
T
F
S
F
E
P
L
S
Site 41
S517
P
L
S
S
A
T
F
S
F
E
P
L
S
S
P
Site 42
S522
T
F
S
F
E
P
L
S
S
P
D
G
P
V
I
Site 43
T538
Q
N
L
R
I
T
G
T
I
T
A
R
E
H
S
Site 44
T540
L
R
I
T
G
T
I
T
A
R
E
H
S
G
T
Site 45
S545
T
I
T
A
R
E
H
S
G
T
G
F
H
P
Y
Site 46
T547
T
A
R
E
H
S
G
T
G
F
H
P
Y
T
L
Site 47
Y552
S
G
T
G
F
H
P
Y
T
L
Y
T
V
K
Y
Site 48
T553
G
T
G
F
H
P
Y
T
L
Y
T
V
K
Y
E
Site 49
Y555
G
F
H
P
Y
T
L
Y
T
V
K
Y
E
T
A
Site 50
T556
F
H
P
Y
T
L
Y
T
V
K
Y
E
T
A
L
Site 51
Y559
Y
T
L
Y
T
V
K
Y
E
T
A
L
D
G
E
Site 52
S569
A
L
D
G
E
N
S
S
G
L
Q
Q
L
A
Y
Site 53
Y576
S
G
L
Q
Q
L
A
Y
H
T
V
N
R
R
Y
Site 54
T578
L
Q
Q
L
A
Y
H
T
V
N
R
R
Y
R
E
Site 55
Y583
Y
H
T
V
N
R
R
Y
R
E
F
L
N
L
Q
Site 56
S623
L
P
F
G
N
M
D
S
D
R
V
E
A
R
K
Site 57
S631
D
R
V
E
A
R
K
S
L
L
E
S
F
L
K
Site 58
S649
A
I
P
E
I
A
N
S
E
E
V
Q
E
F
L
Site 59
S674
V
K
K
P
F
M
V
S
R
I
D
K
M
V
V
Site 60
S682
R
I
D
K
M
V
V
S
A
I
V
D
T
L
K
Site 61
T687
V
V
S
A
I
V
D
T
L
K
T
A
F
P
R
Site 62
T690
A
I
V
D
T
L
K
T
A
F
P
R
S
E
P
Site 63
S695
L
K
T
A
F
P
R
S
E
P
Q
S
P
T
E
Site 64
S699
F
P
R
S
E
P
Q
S
P
T
E
E
L
S
E
Site 65
T701
R
S
E
P
Q
S
P
T
E
E
L
S
E
A
E
Site 66
S705
Q
S
P
T
E
E
L
S
E
A
E
T
E
S
K
Site 67
T709
E
E
L
S
E
A
E
T
E
S
K
P
Q
T
E
Site 68
T715
E
T
E
S
K
P
Q
T
E
G
K
K
A
S
K
Site 69
S721
Q
T
E
G
K
K
A
S
K
S
R
L
R
F
S
Site 70
S723
E
G
K
K
A
S
K
S
R
L
R
F
S
S
S
Site 71
S728
S
K
S
R
L
R
F
S
S
S
K
I
S
P
A
Site 72
S729
K
S
R
L
R
F
S
S
S
K
I
S
P
A
L
Site 73
S730
S
R
L
R
F
S
S
S
K
I
S
P
A
L
S
Site 74
S733
R
F
S
S
S
K
I
S
P
A
L
S
V
T
E
Site 75
S737
S
K
I
S
P
A
L
S
V
T
E
A
Q
D
K
Site 76
Y747
E
A
Q
D
K
I
L
Y
C
L
Q
E
G
S
V
Site 77
S753
L
Y
C
L
Q
E
G
S
V
E
S
E
T
L
S
Site 78
S756
L
Q
E
G
S
V
E
S
E
T
L
S
M
S
A
Site 79
T758
E
G
S
V
E
S
E
T
L
S
M
S
A
M
E
Site 80
S760
S
V
E
S
E
T
L
S
M
S
A
M
E
S
F
Site 81
S762
E
S
E
T
L
S
M
S
A
M
E
S
F
I
E
Site 82
S766
L
S
M
S
A
M
E
S
F
I
E
K
Q
T
K
Site 83
T780
K
L
L
E
M
Q
P
T
K
A
P
E
K
D
P
Site 84
S797
P
P
K
G
R
V
D
S
C
V
S
D
A
A
V
Site 85
S810
A
V
P
A
Q
D
P
S
N
S
D
P
G
T
E
Site 86
S812
P
A
Q
D
P
S
N
S
D
P
G
T
E
T
E
Site 87
T816
P
S
N
S
D
P
G
T
E
T
E
L
A
D
T
Site 88
S869
V
Q
V
A
N
L
T
S
P
Q
R
W
V
Q
Y
Site 89
Y876
S
P
Q
R
W
V
Q
Y
L
R
L
L
Q
E
S
Site 90
S913
A
E
K
Q
A
L
Q
S
L
M
G
V
L
P
D
Site 91
S968
E
F
L
D
L
S
A
S
V
E
E
S
A
A
T
Site 92
S972
L
S
A
S
V
E
E
S
A
A
T
T
S
A
S
Site 93
T975
S
V
E
E
S
A
A
T
T
S
A
S
D
T
P
Site 94
S977
E
E
S
A
A
T
T
S
A
S
D
T
P
G
N
Site 95
S979
S
A
A
T
T
S
A
S
D
T
P
G
N
S
K
Site 96
T981
A
T
T
S
A
S
D
T
P
G
N
S
K
R
M
Site 97
S985
A
S
D
T
P
G
N
S
K
R
M
G
V
S
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation