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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
WASF1
Full Name:
Wiskott-Aldrich syndrome protein family member 1
Alias:
KIAA0269; Protein WAVE-1; SCAR1; Verprolin homology domain-containing protein 1; WAS protein family, member 1; WAS1; WASP-family protein member 1; WAVE; WAVE1
Type:
Cytoskeletal protein
Mass (Da):
61652
Number AA:
559
UniProt ID:
Q92558
International Prot ID:
IPI00022007
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005739
GO:0005856
Uniprot
OncoNet
Molecular Function:
GO:0003779
GO:0005488
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006461
GO:0006928
GO:0008154
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T16
D
P
R
H
L
C
H
T
A
L
P
R
G
I
K
Site 2
T30
K
N
E
L
E
C
V
T
N
I
S
L
A
N
I
Site 3
S33
L
E
C
V
T
N
I
S
L
A
N
I
I
R
Q
Site 4
S42
A
N
I
I
R
Q
L
S
S
L
S
K
Y
A
E
Site 5
S43
N
I
I
R
Q
L
S
S
L
S
K
Y
A
E
D
Site 6
S45
I
R
Q
L
S
S
L
S
K
Y
A
E
D
I
F
Site 7
Y47
Q
L
S
S
L
S
K
Y
A
E
D
I
F
G
E
Site 8
S61
E
L
F
N
E
A
H
S
F
S
F
R
V
N
S
Site 9
S63
F
N
E
A
H
S
F
S
F
R
V
N
S
L
Q
Site 10
S68
S
F
S
F
R
V
N
S
L
Q
E
R
V
D
R
Site 11
S77
Q
E
R
V
D
R
L
S
V
S
V
T
Q
L
D
Site 12
S79
R
V
D
R
L
S
V
S
V
T
Q
L
D
P
K
Site 13
T81
D
R
L
S
V
S
V
T
Q
L
D
P
K
E
E
Site 14
S91
D
P
K
E
E
E
L
S
L
Q
D
I
T
M
R
Site 15
T96
E
L
S
L
Q
D
I
T
M
R
K
A
F
R
S
Site 16
S103
T
M
R
K
A
F
R
S
S
T
I
Q
D
Q
Q
Site 17
S104
M
R
K
A
F
R
S
S
T
I
Q
D
Q
Q
L
Site 18
T105
R
K
A
F
R
S
S
T
I
Q
D
Q
Q
L
F
Site 19
T116
Q
Q
L
F
D
R
K
T
L
P
I
P
L
Q
E
Site 20
Y125
P
I
P
L
Q
E
T
Y
D
V
C
E
Q
P
P
Site 21
T138
P
P
P
L
N
I
L
T
P
Y
R
D
D
G
K
Site 22
Y140
P
L
N
I
L
T
P
Y
R
D
D
G
K
E
G
Site 23
Y151
G
K
E
G
L
K
F
Y
T
N
P
S
Y
F
F
Site 24
Y156
K
F
Y
T
N
P
S
Y
F
F
D
L
W
K
E
Site 25
T169
K
E
K
M
L
Q
D
T
E
D
K
R
K
E
K
Site 26
S233
E
V
A
N
G
P
A
S
H
F
E
T
R
P
Q
Site 27
T237
G
P
A
S
H
F
E
T
R
P
Q
T
Y
V
D
Site 28
Y242
F
E
T
R
P
Q
T
Y
V
D
H
M
D
G
S
Site 29
S249
Y
V
D
H
M
D
G
S
Y
S
L
S
A
L
P
Site 30
Y250
V
D
H
M
D
G
S
Y
S
L
S
A
L
P
F
Site 31
S251
D
H
M
D
G
S
Y
S
L
S
A
L
P
F
S
Site 32
S253
M
D
G
S
Y
S
L
S
A
L
P
F
S
Q
M
Site 33
T265
S
Q
M
S
E
L
L
T
R
A
E
E
R
V
L
Site 34
T295
G
D
A
K
P
I
P
T
C
I
S
S
A
T
G
Site 35
S298
K
P
I
P
T
C
I
S
S
A
T
G
L
I
E
Site 36
S310
L
I
E
N
R
P
Q
S
P
A
T
G
R
T
P
Site 37
T313
N
R
P
Q
S
P
A
T
G
R
T
P
V
F
V
Site 38
T316
Q
S
P
A
T
G
R
T
P
V
F
V
S
P
T
Site 39
S321
G
R
T
P
V
F
V
S
P
T
P
P
P
P
P
Site 40
T323
T
P
V
F
V
S
P
T
P
P
P
P
P
P
P
Site 41
S333
P
P
P
P
P
L
P
S
A
L
S
T
S
S
L
Site 42
S336
P
P
L
P
S
A
L
S
T
S
S
L
R
A
S
Site 43
T337
P
L
P
S
A
L
S
T
S
S
L
R
A
S
M
Site 44
S339
P
S
A
L
S
T
S
S
L
R
A
S
M
T
S
Site 45
S343
S
T
S
S
L
R
A
S
M
T
S
T
P
P
P
Site 46
T345
S
S
L
R
A
S
M
T
S
T
P
P
P
P
V
Site 47
S346
S
L
R
A
S
M
T
S
T
P
P
P
P
V
P
Site 48
T347
L
R
A
S
M
T
S
T
P
P
P
P
V
P
P
Site 49
T361
P
P
P
P
P
P
A
T
A
L
Q
A
P
A
V
Site 50
S397
A
P
P
L
V
Q
P
S
P
P
V
A
R
A
A
Site 51
S440
P
P
P
G
I
R
P
S
S
P
V
T
V
T
A
Site 52
S441
P
P
G
I
R
P
S
S
P
V
T
V
T
A
L
Site 53
S453
T
A
L
A
H
P
P
S
G
L
H
P
T
P
S
Site 54
T458
P
P
S
G
L
H
P
T
P
S
T
A
P
G
P
Site 55
S460
S
G
L
H
P
T
P
S
T
A
P
G
P
H
V
Site 56
S473
H
V
P
L
M
P
P
S
P
P
S
Q
V
I
P
Site 57
S476
L
M
P
P
S
P
P
S
Q
V
I
P
A
S
E
Site 58
S482
P
S
Q
V
I
P
A
S
E
P
K
R
H
P
S
Site 59
S489
S
E
P
K
R
H
P
S
T
L
P
V
I
S
D
Site 60
T490
E
P
K
R
H
P
S
T
L
P
V
I
S
D
A
Site 61
Y543
S
R
R
I
A
V
E
Y
S
D
S
E
D
D
S
Site 62
S544
R
R
I
A
V
E
Y
S
D
S
E
D
D
S
E
Site 63
S546
I
A
V
E
Y
S
D
S
E
D
D
S
E
F
D
Site 64
S550
Y
S
D
S
E
D
D
S
E
F
D
E
V
D
W
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation