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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SPOCK2
Full Name:
Testican-2
Alias:
flj97039; KIAA0275; sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2; sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 isoform 2; spock2; testican-2; ticn2
Type:
Mass (Da):
46779
Number AA:
424
UniProt ID:
Q92563
International Prot ID:
IPI00006128
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005578
Uniprot
OncoNet
Molecular Function:
GO:0005509
PhosphoSite+
KinaseNET
Biological Process:
GO:0030198
GO:0045595
GO:0007165
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T34
K
G
L
K
E
G
E
T
P
G
N
F
M
E
D
Site 2
S46
M
E
D
E
Q
W
L
S
S
I
S
Q
Y
S
G
Site 3
S47
E
D
E
Q
W
L
S
S
I
S
Q
Y
S
G
K
Site 4
S49
E
Q
W
L
S
S
I
S
Q
Y
S
G
K
I
K
Site 5
Y51
W
L
S
S
I
S
Q
Y
S
G
K
I
K
H
W
Site 6
S52
L
S
S
I
S
Q
Y
S
G
K
I
K
H
W
N
Site 7
Y69
R
D
E
V
E
D
D
Y
I
K
S
W
E
D
N
Site 8
T85
Q
G
D
E
A
L
D
T
T
K
D
P
C
Q
K
Site 9
T86
G
D
E
A
L
D
T
T
K
D
P
C
Q
K
V
Site 10
T125
E
H
R
I
K
Q
P
T
V
K
L
H
G
N
K
Site 11
S150
Q
L
A
S
V
C
G
S
D
G
H
T
Y
S
S
Site 12
T154
V
C
G
S
D
G
H
T
Y
S
S
V
C
K
L
Site 13
Y155
C
G
S
D
G
H
T
Y
S
S
V
C
K
L
E
Site 14
S156
G
S
D
G
H
T
Y
S
S
V
C
K
L
E
Q
Site 15
S157
S
D
G
H
T
Y
S
S
V
C
K
L
E
Q
Q
Site 16
T184
E
G
P
C
P
C
P
T
E
Q
A
A
T
S
T
Site 17
S222
F
Q
L
L
H
E
N
S
K
Q
N
G
S
A
S
Site 18
S227
E
N
S
K
Q
N
G
S
A
S
S
V
A
G
P
Site 19
S229
S
K
Q
N
G
S
A
S
S
V
A
G
P
A
S
Site 20
S230
K
Q
N
G
S
A
S
S
V
A
G
P
A
S
G
Site 21
S236
S
S
V
A
G
P
A
S
G
L
D
K
S
L
G
Site 22
S241
P
A
S
G
L
D
K
S
L
G
A
S
C
K
D
Site 23
S245
L
D
K
S
L
G
A
S
C
K
D
S
I
G
W
Site 24
S249
L
G
A
S
C
K
D
S
I
G
W
M
F
S
K
Site 25
S255
D
S
I
G
W
M
F
S
K
L
D
T
S
A
D
Site 26
S260
M
F
S
K
L
D
T
S
A
D
L
F
L
D
Q
Site 27
T291
P
F
F
N
S
C
D
T
Y
K
D
G
R
V
S
Site 28
Y292
F
F
N
S
C
D
T
Y
K
D
G
R
V
S
T
Site 29
Y342
P
S
C
D
E
D
G
Y
Y
R
K
M
Q
C
D
Site 30
Y343
S
C
D
E
D
G
Y
Y
R
K
M
Q
C
D
Q
Site 31
T366
D
Q
L
G
L
E
L
T
G
T
R
T
H
G
S
Site 32
T368
L
G
L
E
L
T
G
T
R
T
H
G
S
P
D
Site 33
S373
T
G
T
R
T
H
G
S
P
D
C
D
D
I
V
Site 34
S388
G
F
S
G
D
F
G
S
G
V
G
W
E
D
E
Site 35
T400
E
D
E
E
E
K
E
T
E
E
A
G
E
E
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation