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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF592
Full Name:
Zinc finger protein 592
Alias:
KIAA0211; Z592; ZN592
Type:
Uncharacterized protein
Mass (Da):
137528
Number AA:
1267
UniProt ID:
Q92610
International Prot ID:
IPI00022460
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0005634
GO:0043226
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0008270
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
GO:0045449
GO:0006350
GO:0006355
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T6
_
_
M
G
D
M
K
T
P
D
F
D
D
L
L
Site 2
S23
F
D
I
P
D
P
T
S
L
D
A
K
E
A
I
Site 3
T32
D
A
K
E
A
I
Q
T
P
S
E
E
N
E
S
Site 4
S34
K
E
A
I
Q
T
P
S
E
E
N
E
S
P
L
Site 5
S39
T
P
S
E
E
N
E
S
P
L
K
P
P
G
I
Site 6
S51
P
G
I
C
M
D
E
S
V
S
L
S
H
S
G
Site 7
S53
I
C
M
D
E
S
V
S
L
S
H
S
G
S
A
Site 8
S55
M
D
E
S
V
S
L
S
H
S
G
S
A
P
D
Site 9
S57
E
S
V
S
L
S
H
S
G
S
A
P
D
V
P
Site 10
S78
K
N
T
S
R
Q
E
S
F
E
A
E
K
D
H
Site 11
T87
E
A
E
K
D
H
I
T
P
S
L
L
H
N
G
Site 12
S89
E
K
D
H
I
T
P
S
L
L
H
N
G
F
R
Site 13
S98
L
H
N
G
F
R
G
S
D
L
P
P
D
P
H
Site 14
S119
S
T
F
M
N
G
D
S
A
R
S
F
P
G
K
Site 15
S122
M
N
G
D
S
A
R
S
F
P
G
K
L
E
P
Site 16
S132
G
K
L
E
P
P
K
S
E
P
L
P
T
F
N
Site 17
T137
P
K
S
E
P
L
P
T
F
N
Q
F
S
P
I
Site 18
S142
L
P
T
F
N
Q
F
S
P
I
S
S
P
E
P
Site 19
S145
F
N
Q
F
S
P
I
S
S
P
E
P
E
D
P
Site 20
S146
N
Q
F
S
P
I
S
S
P
E
P
E
D
P
I
Site 21
S165
F
G
I
K
P
K
H
S
D
S
Y
F
P
P
P
Site 22
S167
I
K
P
K
H
S
D
S
Y
F
P
P
P
L
G
Site 23
Y168
K
P
K
H
S
D
S
Y
F
P
P
P
L
G
C
Site 24
S214
P
E
P
L
P
L
G
S
Q
Q
E
H
E
Q
S
Site 25
T225
H
E
Q
S
G
Q
N
T
V
E
P
H
K
D
P
Site 26
T235
P
H
K
D
P
D
A
T
R
F
F
G
E
A
L
Site 27
S246
G
E
A
L
E
F
N
S
H
P
S
N
S
I
G
Site 28
S249
L
E
F
N
S
H
P
S
N
S
I
G
E
S
K
Site 29
S251
F
N
S
H
P
S
N
S
I
G
E
S
K
G
L
Site 30
S255
P
S
N
S
I
G
E
S
K
G
L
A
R
E
L
Site 31
T264
G
L
A
R
E
L
G
T
C
S
S
V
P
P
R
Site 32
S266
A
R
E
L
G
T
C
S
S
V
P
P
R
Q
R
Site 33
S267
R
E
L
G
T
C
S
S
V
P
P
R
Q
R
L
Site 34
S279
Q
R
L
K
P
A
H
S
K
L
S
S
C
V
A
Site 35
S298
L
Q
A
K
R
V
A
S
V
T
K
E
D
Q
P
Site 36
T300
A
K
R
V
A
S
V
T
K
E
D
Q
P
G
H
Site 37
S312
P
G
H
T
K
D
L
S
G
P
T
K
E
S
S
Site 38
S318
L
S
G
P
T
K
E
S
S
K
G
S
P
K
M
Site 39
S319
S
G
P
T
K
E
S
S
K
G
S
P
K
M
P
Site 40
S322
T
K
E
S
S
K
G
S
P
K
M
P
K
S
P
Site 41
S328
G
S
P
K
M
P
K
S
P
K
S
P
R
S
P
Site 42
S331
K
M
P
K
S
P
K
S
P
R
S
P
L
E
A
Site 43
S334
K
S
P
K
S
P
R
S
P
L
E
A
T
R
K
Site 44
T339
P
R
S
P
L
E
A
T
R
K
S
I
K
P
S
Site 45
S342
P
L
E
A
T
R
K
S
I
K
P
S
D
S
P
Site 46
S346
T
R
K
S
I
K
P
S
D
S
P
R
S
I
C
Site 47
S348
K
S
I
K
P
S
D
S
P
R
S
I
C
S
D
Site 48
S351
K
P
S
D
S
P
R
S
I
C
S
D
S
S
S
Site 49
S354
D
S
P
R
S
I
C
S
D
S
S
S
K
G
S
Site 50
S356
P
R
S
I
C
S
D
S
S
S
K
G
S
P
S
Site 51
S357
R
S
I
C
S
D
S
S
S
K
G
S
P
S
V
Site 52
S358
S
I
C
S
D
S
S
S
K
G
S
P
S
V
A
Site 53
S361
S
D
S
S
S
K
G
S
P
S
V
A
A
S
S
Site 54
S363
S
S
S
K
G
S
P
S
V
A
A
S
S
P
P
Site 55
S367
G
S
P
S
V
A
A
S
S
P
P
A
I
P
K
Site 56
S368
S
P
S
V
A
A
S
S
P
P
A
I
P
K
V
Site 57
T379
I
P
K
V
R
I
K
T
I
K
T
S
S
G
E
Site 58
T382
V
R
I
K
T
I
K
T
S
S
G
E
I
K
R
Site 59
S384
I
K
T
I
K
T
S
S
G
E
I
K
R
T
V
Site 60
T390
S
S
G
E
I
K
R
T
V
T
R
I
L
P
D
Site 61
T392
G
E
I
K
R
T
V
T
R
I
L
P
D
P
D
Site 62
S402
L
P
D
P
D
D
P
S
K
S
P
V
G
S
P
Site 63
S404
D
P
D
D
P
S
K
S
P
V
G
S
P
L
G
Site 64
S408
P
S
K
S
P
V
G
S
P
L
G
S
A
I
A
Site 65
S419
S
A
I
A
E
A
P
S
E
M
P
G
D
E
V
Site 66
T437
E
H
F
P
E
A
G
T
N
S
G
S
P
Q
G
Site 67
S441
E
A
G
T
N
S
G
S
P
Q
G
A
R
K
G
Site 68
S451
G
A
R
K
G
D
E
S
M
T
K
A
S
D
S
Site 69
T453
R
K
G
D
E
S
M
T
K
A
S
D
S
S
S
Site 70
S456
D
E
S
M
T
K
A
S
D
S
S
S
P
S
C
Site 71
S458
S
M
T
K
A
S
D
S
S
S
P
S
C
S
S
Site 72
S459
M
T
K
A
S
D
S
S
S
P
S
C
S
S
G
Site 73
S460
T
K
A
S
D
S
S
S
P
S
C
S
S
G
P
Site 74
S462
A
S
D
S
S
S
P
S
C
S
S
G
P
R
V
Site 75
S464
D
S
S
S
P
S
C
S
S
G
P
R
V
P
K
Site 76
S465
S
S
S
P
S
C
S
S
G
P
R
V
P
K
G
Site 77
S477
P
K
G
A
A
P
G
S
Q
T
G
K
K
Q
Q
Site 78
S523
A
A
S
V
T
A
K
S
S
V
Q
R
R
S
Q
Site 79
S524
A
S
V
T
A
K
S
S
V
Q
R
R
S
Q
P
Site 80
S529
K
S
S
V
Q
R
R
S
Q
P
Q
L
T
Q
M
Site 81
T534
R
R
S
Q
P
Q
L
T
Q
M
S
V
P
L
V
Site 82
Y568
S
S
N
P
V
P
L
Y
A
P
N
L
S
P
P
Site 83
S573
P
L
Y
A
P
N
L
S
P
P
A
D
S
R
I
Site 84
S578
N
L
S
P
P
A
D
S
R
I
H
V
P
A
S
Site 85
S601
D
A
F
A
L
E
K
S
L
S
Q
H
Y
G
R
Site 86
S603
F
A
L
E
K
S
L
S
Q
H
Y
G
R
R
S
Site 87
Y606
E
K
S
L
S
Q
H
Y
G
R
R
S
V
H
I
Site 88
S610
S
Q
H
Y
G
R
R
S
V
H
I
E
V
L
C
Site 89
S631
L
L
F
F
N
K
C
S
L
L
R
H
A
R
D
Site 90
S678
A
P
A
A
P
A
P
S
S
S
P
K
H
G
L
Site 91
S679
P
A
A
P
A
P
S
S
S
P
K
H
G
L
T
Site 92
S680
A
A
P
A
P
S
S
S
P
K
H
G
L
T
S
Site 93
T686
S
S
P
K
H
G
L
T
S
G
S
A
S
P
P
Site 94
S687
S
P
K
H
G
L
T
S
G
S
A
S
P
P
P
Site 95
S689
K
H
G
L
T
S
G
S
A
S
P
P
P
P
A
Site 96
S691
G
L
T
S
G
S
A
S
P
P
P
P
A
L
P
Site 97
T734
A
A
H
F
Q
R
T
T
E
E
T
E
G
L
T
Site 98
Y768
I
H
A
H
K
S
P
Y
C
C
P
E
C
G
V
Site 99
Y781
G
V
L
C
R
S
A
Y
F
Q
T
H
V
K
E
Site 100
Y793
V
K
E
N
C
L
H
Y
A
R
K
V
G
Y
R
Site 101
S816
L
T
L
A
L
L
K
S
H
I
Q
E
R
H
C
Site 102
T838
F
C
P
M
A
F
K
T
A
S
S
T
A
D
H
Site 103
S840
P
M
A
F
K
T
A
S
S
T
A
D
H
S
A
Site 104
S841
M
A
F
K
T
A
S
S
T
A
D
H
S
A
T
Site 105
T842
A
F
K
T
A
S
S
T
A
D
H
S
A
T
Q
Site 106
S846
A
S
S
T
A
D
H
S
A
T
Q
H
P
T
Q
Site 107
T848
S
T
A
D
H
S
A
T
Q
H
P
T
Q
P
H
Site 108
T852
H
S
A
T
Q
H
P
T
Q
P
H
R
P
S
Q
Site 109
S858
P
T
Q
P
H
R
P
S
Q
L
I
Y
K
C
S
Site 110
Y862
H
R
P
S
Q
L
I
Y
K
C
S
C
E
M
V
Site 111
Y881
R
H
I
Q
Q
H
F
Y
Q
N
V
S
K
T
Q
Site 112
T887
F
Y
Q
N
V
S
K
T
Q
V
G
V
F
K
C
Site 113
S913
E
L
M
Q
H
V
K
S
T
H
G
V
P
R
N
Site 114
S925
P
R
N
V
D
E
L
S
S
L
Q
S
S
A
D
Site 115
S926
R
N
V
D
E
L
S
S
L
Q
S
S
A
D
T
Site 116
S929
D
E
L
S
S
L
Q
S
S
A
D
T
S
S
S
Site 117
S930
E
L
S
S
L
Q
S
S
A
D
T
S
S
S
R
Site 118
T933
S
L
Q
S
S
A
D
T
S
S
S
R
P
G
S
Site 119
S934
L
Q
S
S
A
D
T
S
S
S
R
P
G
S
R
Site 120
S935
Q
S
S
A
D
T
S
S
S
R
P
G
S
R
V
Site 121
S936
S
S
A
D
T
S
S
S
R
P
G
S
R
V
P
Site 122
S940
T
S
S
S
R
P
G
S
R
V
P
T
E
P
P
Site 123
T944
R
P
G
S
R
V
P
T
E
P
P
A
T
S
V
Site 124
T949
V
P
T
E
P
P
A
T
S
V
A
A
R
S
S
Site 125
S950
P
T
E
P
P
A
T
S
V
A
A
R
S
S
S
Site 126
S955
A
T
S
V
A
A
R
S
S
S
L
P
S
G
R
Site 127
S956
T
S
V
A
A
R
S
S
S
L
P
S
G
R
W
Site 128
S957
S
V
A
A
R
S
S
S
L
P
S
G
R
W
G
Site 129
S960
A
R
S
S
S
L
P
S
G
R
W
G
R
P
E
Site 130
T981
A
R
P
R
L
R
N
T
G
W
T
C
Q
E
C
Site 131
Y998
W
V
P
D
R
E
S
Y
V
S
H
M
K
K
S
Site 132
S1000
P
D
R
E
S
Y
V
S
H
M
K
K
S
H
G
Site 133
S1005
Y
V
S
H
M
K
K
S
H
G
R
T
L
K
R
Site 134
T1009
M
K
K
S
H
G
R
T
L
K
R
Y
P
C
R
Site 135
Y1013
H
G
R
T
L
K
R
Y
P
C
R
Q
C
E
Q
Site 136
T1024
Q
C
E
Q
S
F
H
T
P
N
S
L
R
K
H
Site 137
S1027
Q
S
F
H
T
P
N
S
L
R
K
H
I
R
N
Site 138
T1038
H
I
R
N
N
H
D
T
V
K
K
F
Y
T
C
Site 139
S1052
C
G
Y
C
T
E
D
S
P
S
F
P
R
P
S
Site 140
S1054
Y
C
T
E
D
S
P
S
F
P
R
P
S
L
L
Site 141
S1059
S
P
S
F
P
R
P
S
L
L
E
S
H
I
S
Site 142
S1063
P
R
P
S
L
L
E
S
H
I
S
L
M
H
G
Site 143
S1066
S
L
L
E
S
H
I
S
L
M
H
G
I
R
N
Site 144
S1077
G
I
R
N
P
D
L
S
Q
T
S
K
V
K
P
Site 145
T1079
R
N
P
D
L
S
Q
T
S
K
V
K
P
P
G
Site 146
S1080
N
P
D
L
S
Q
T
S
K
V
K
P
P
G
G
Site 147
S1089
V
K
P
P
G
G
H
S
P
Q
V
N
H
L
K
Site 148
S1100
N
H
L
K
R
P
V
S
G
V
G
D
A
P
G
Site 149
S1109
V
G
D
A
P
G
T
S
N
G
A
T
V
S
S
Site 150
T1113
P
G
T
S
N
G
A
T
V
S
S
T
K
R
H
Site 151
S1115
T
S
N
G
A
T
V
S
S
T
K
R
H
K
S
Site 152
S1116
S
N
G
A
T
V
S
S
T
K
R
H
K
S
L
Site 153
T1117
N
G
A
T
V
S
S
T
K
R
H
K
S
L
F
Site 154
S1122
S
S
T
K
R
H
K
S
L
F
Q
C
A
K
C
Site 155
S1135
K
C
S
F
A
T
D
S
G
L
E
F
Q
S
H
Site 156
S1141
D
S
G
L
E
F
Q
S
H
I
P
Q
H
Q
V
Site 157
S1151
P
Q
H
Q
V
D
S
S
T
A
Q
C
L
L
C
Site 158
T1152
Q
H
Q
V
D
S
S
T
A
Q
C
L
L
C
G
Site 159
S1205
V
A
E
P
E
E
G
S
G
E
E
V
P
M
E
Site 160
S1227
E
C
A
G
E
P
L
S
A
D
P
E
A
R
R
Site 161
S1250
D
G
G
H
N
D
H
S
Q
P
Q
A
S
Q
D
Site 162
S1255
D
H
S
Q
P
Q
A
S
Q
D
Q
D
S
H
T
Site 163
S1260
Q
A
S
Q
D
Q
D
S
H
T
L
S
P
Q
V
Site 164
T1262
S
Q
D
Q
D
S
H
T
L
S
P
Q
V
_
_
Site 165
S1264
D
Q
D
S
H
T
L
S
P
Q
V
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation