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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LARP5
Full Name:
La-related protein 4B
Alias:
KIAA0217; La ribonucleoprotein domain family 5; La ribonucleoprotein domain family member 4B; La ribonucleoprotein domain family member 5; La ribonucleoprotein domain family, member 4B; La-related protein 5
Type:
RNA binding protein
Mass (Da):
80552
Number AA:
738
UniProt ID:
Q92615
International Prot ID:
not found
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0003723
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T15
K
V
V
A
E
P
Q
T
Q
R
V
Q
E
G
K
Site 2
S24
R
V
Q
E
G
K
D
S
A
H
L
M
N
G
P
Site 3
S33
H
L
M
N
G
P
I
S
Q
T
T
S
Q
T
S
Site 4
T35
M
N
G
P
I
S
Q
T
T
S
Q
T
S
S
I
Site 5
T36
N
G
P
I
S
Q
T
T
S
Q
T
S
S
I
P
Site 6
S37
G
P
I
S
Q
T
T
S
Q
T
S
S
I
P
P
Site 7
S40
S
Q
T
T
S
Q
T
S
S
I
P
P
L
S
Q
Site 8
S41
Q
T
T
S
Q
T
S
S
I
P
P
L
S
Q
V
Site 9
S46
T
S
S
I
P
P
L
S
Q
V
P
A
T
K
V
Site 10
T51
P
L
S
Q
V
P
A
T
K
V
S
E
L
N
P
Site 11
S98
A
D
R
G
P
Q
G
S
D
A
N
G
D
G
D
Site 12
S132
N
A
L
A
L
G
P
S
E
Y
D
S
L
P
E
Site 13
Y134
L
A
L
G
P
S
E
Y
D
S
L
P
E
N
S
Site 14
S136
L
G
P
S
E
Y
D
S
L
P
E
N
S
E
T
Site 15
T143
S
L
P
E
N
S
E
T
G
G
N
E
S
Q
P
Site 16
S148
S
E
T
G
G
N
E
S
Q
P
D
S
Q
E
D
Site 17
S152
G
N
E
S
Q
P
D
S
Q
E
D
P
R
E
V
Site 18
T163
P
R
E
V
L
K
K
T
L
E
F
C
L
S
R
Site 19
S169
K
T
L
E
F
C
L
S
R
E
N
L
A
S
D
Site 20
S175
L
S
R
E
N
L
A
S
D
M
Y
L
I
S
Q
Site 21
Y178
E
N
L
A
S
D
M
Y
L
I
S
Q
M
D
S
Site 22
S181
A
S
D
M
Y
L
I
S
Q
M
D
S
D
Q
Y
Site 23
S185
Y
L
I
S
Q
M
D
S
D
Q
Y
V
P
I
T
Site 24
Y188
S
Q
M
D
S
D
Q
Y
V
P
I
T
T
V
A
Site 25
T192
S
D
Q
Y
V
P
I
T
T
V
A
N
L
D
H
Site 26
S244
I
V
I
L
R
E
I
S
E
S
T
P
V
E
E
Site 27
S246
I
L
R
E
I
S
E
S
T
P
V
E
E
V
E
Site 28
T247
L
R
E
I
S
E
S
T
P
V
E
E
V
E
A
Site 29
Y291
D
A
Q
Q
A
Y
K
Y
L
R
E
E
V
K
T
Site 30
T298
Y
L
R
E
E
V
K
T
F
Q
G
K
P
I
K
Site 31
S330
G
F
R
P
L
D
V
S
L
Y
A
Q
Q
R
Y
Site 32
Y332
R
P
L
D
V
S
L
Y
A
Q
Q
R
Y
A
T
Site 33
Y337
S
L
Y
A
Q
Q
R
Y
A
T
S
F
Y
F
P
Site 34
Y342
Q
R
Y
A
T
S
F
Y
F
P
P
M
Y
S
P
Site 35
Y347
S
F
Y
F
P
P
M
Y
S
P
Q
Q
Q
F
P
Site 36
Y356
P
Q
Q
Q
F
P
L
Y
S
L
I
T
P
Q
T
Site 37
T363
Y
S
L
I
T
P
Q
T
W
S
A
T
H
S
Y
Site 38
S365
L
I
T
P
Q
T
W
S
A
T
H
S
Y
L
D
Site 39
S369
Q
T
W
S
A
T
H
S
Y
L
D
P
P
L
V
Site 40
Y370
T
W
S
A
T
H
S
Y
L
D
P
P
L
V
T
Site 41
S398
P
A
F
K
P
A
A
S
P
L
T
S
L
R
Q
Site 42
S402
P
A
A
S
P
L
T
S
L
R
Q
Y
P
P
R
Site 43
Y406
P
L
T
S
L
R
Q
Y
P
P
R
S
R
N
P
Site 44
S410
L
R
Q
Y
P
P
R
S
R
N
P
S
K
S
H
Site 45
S414
P
P
R
S
R
N
P
S
K
S
H
L
R
H
A
Site 46
S416
R
S
R
N
P
S
K
S
H
L
R
H
A
I
P
Site 47
S424
H
L
R
H
A
I
P
S
A
E
R
G
P
G
L
Site 48
S434
R
G
P
G
L
L
E
S
P
S
I
F
N
F
T
Site 49
S451
R
L
I
N
G
V
R
S
P
Q
T
R
Q
A
G
Site 50
T460
Q
T
R
Q
A
G
Q
T
R
T
R
I
Q
N
P
Site 51
S468
R
T
R
I
Q
N
P
S
A
Y
A
K
R
E
A
Site 52
Y470
R
I
Q
N
P
S
A
Y
A
K
R
E
A
G
P
Site 53
S484
P
G
R
V
E
P
G
S
L
E
S
S
P
G
L
Site 54
S488
E
P
G
S
L
E
S
S
P
G
L
G
R
G
R
Site 55
S498
L
G
R
G
R
K
N
S
F
G
Y
R
K
K
R
Site 56
T510
K
K
R
E
E
K
F
T
S
S
Q
T
Q
S
P
Site 57
S511
K
R
E
E
K
F
T
S
S
Q
T
Q
S
P
T
Site 58
S512
R
E
E
K
F
T
S
S
Q
T
Q
S
P
T
P
Site 59
T514
E
K
F
T
S
S
Q
T
Q
S
P
T
P
P
K
Site 60
S516
F
T
S
S
Q
T
Q
S
P
T
P
P
K
P
P
Site 61
T518
S
S
Q
T
Q
S
P
T
P
P
K
P
P
S
P
Site 62
S524
P
T
P
P
K
P
P
S
P
S
F
E
L
G
L
Site 63
S526
P
P
K
P
P
S
P
S
F
E
L
G
L
S
S
Site 64
S532
P
S
F
E
L
G
L
S
S
F
P
P
L
P
G
Site 65
S533
S
F
E
L
G
L
S
S
F
P
P
L
P
G
A
Site 66
T546
G
A
A
G
N
L
K
T
E
D
L
F
E
N
R
Site 67
S562
S
S
L
I
I
G
P
S
K
E
R
T
L
S
A
Site 68
T566
I
G
P
S
K
E
R
T
L
S
A
D
A
S
V
Site 69
S568
P
S
K
E
R
T
L
S
A
D
A
S
V
N
T
Site 70
S585
V
V
V
S
R
E
P
S
V
P
A
S
C
A
V
Site 71
S589
R
E
P
S
V
P
A
S
C
A
V
S
A
T
Y
Site 72
S593
V
P
A
S
C
A
V
S
A
T
Y
E
R
S
P
Site 73
T595
A
S
C
A
V
S
A
T
Y
E
R
S
P
S
P
Site 74
Y596
S
C
A
V
S
A
T
Y
E
R
S
P
S
P
A
Site 75
S599
V
S
A
T
Y
E
R
S
P
S
P
A
H
L
P
Site 76
S601
A
T
Y
E
R
S
P
S
P
A
H
L
P
D
D
Site 77
T618
V
A
E
K
Q
R
E
T
H
S
V
D
R
L
P
Site 78
S620
E
K
Q
R
E
T
H
S
V
D
R
L
P
S
A
Site 79
S626
H
S
V
D
R
L
P
S
A
L
T
A
T
A
C
Site 80
S635
L
T
A
T
A
C
K
S
V
Q
V
N
G
A
A
Site 81
T643
V
Q
V
N
G
A
A
T
E
L
R
K
P
S
Y
Site 82
S649
A
T
E
L
R
K
P
S
Y
A
E
I
C
Q
R
Site 83
Y650
T
E
L
R
K
P
S
Y
A
E
I
C
Q
R
T
Site 84
S658
A
E
I
C
Q
R
T
S
K
E
P
P
S
S
P
Site 85
S663
R
T
S
K
E
P
P
S
S
P
L
Q
P
Q
K
Site 86
S664
T
S
K
E
P
P
S
S
P
L
Q
P
Q
K
E
Site 87
T676
Q
K
E
Q
K
P
N
T
V
G
C
G
K
E
E
Site 88
Y693
L
A
E
P
A
E
R
Y
R
E
P
P
A
L
K
Site 89
S701
R
E
P
P
A
L
K
S
T
P
G
A
P
R
D
Site 90
T702
E
P
P
A
L
K
S
T
P
G
A
P
R
D
Q
Site 91
S718
R
P
A
G
G
R
P
S
P
S
A
M
G
K
R
Site 92
S720
A
G
G
R
P
S
P
S
A
M
G
K
R
L
S
Site 93
S727
S
A
M
G
K
R
L
S
R
E
Q
S
T
P
P
Site 94
S731
K
R
L
S
R
E
Q
S
T
P
P
K
S
P
Q
Site 95
T732
R
L
S
R
E
Q
S
T
P
P
K
S
P
Q
_
Site 96
S736
E
Q
S
T
P
P
K
S
P
Q
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation