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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
HMHA1
Full Name:
Minor histocompatibility protein HA-1
Alias:
HA-1; histocompatibility (minor) HA-1; histocompatibility HA-1; HLA-HA1; KIAA0223; minor histocompatibility antigen HA-1
Type:
Cell surface protein
Mass (Da):
124614
Number AA:
1136
UniProt ID:
Q92619
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005622
Uniprot
OncoNet
Molecular Function:
GO:0005096
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0007242
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T12
K
K
R
E
L
M
K
T
P
S
I
S
K
K
N
Site 2
S14
R
E
L
M
K
T
P
S
I
S
K
K
N
R
A
Site 3
S23
S
K
K
N
R
A
G
S
P
S
P
Q
P
S
G
Site 4
S25
K
N
R
A
G
S
P
S
P
Q
P
S
G
E
L
Site 5
S29
G
S
P
S
P
Q
P
S
G
E
L
P
R
K
D
Site 6
S46
D
A
V
F
P
G
P
S
L
E
P
P
A
G
S
Site 7
S54
K
N
R
A
G
S
P
S
P
Q
P
S
G
E
L
Site 8
T61
S
G
V
K
A
T
G
T
L
K
R
P
T
S
L
Site 9
T66
T
G
T
L
K
R
P
T
S
L
S
R
H
A
S
Site 10
S67
G
T
L
K
R
P
T
S
L
S
R
H
A
S
A
Site 11
S69
L
K
R
P
T
S
L
S
R
H
A
S
A
A
G
Site 12
S73
T
S
L
S
R
H
A
S
A
A
G
F
P
L
S
Site 13
S84
F
P
L
S
G
A
A
S
W
T
L
G
R
S
H
Site 14
T86
L
S
G
A
A
S
W
T
L
G
R
S
H
R
S
Site 15
S90
A
S
W
T
L
G
R
S
H
R
S
P
L
T
A
Site 16
S93
T
L
G
R
S
H
R
S
P
L
T
A
A
S
P
Site 17
T96
R
S
H
R
S
P
L
T
A
A
S
P
G
E
L
Site 18
S99
R
S
P
L
T
A
A
S
P
G
E
L
P
T
E
Site 19
T105
A
S
P
G
E
L
P
T
E
G
A
G
P
D
V
Site 20
Y168
M
H
Q
I
I
S
K
Y
P
L
L
N
T
V
E
Site 21
Y192
A
K
V
K
A
F
H
Y
E
S
N
N
D
L
E
Site 22
S239
L
A
V
P
P
G
D
S
S
Q
S
M
E
S
L
Site 23
S240
A
V
P
P
G
D
S
S
Q
S
M
E
S
L
Y
Site 24
S242
P
P
G
D
S
S
Q
S
M
E
S
L
Y
G
P
Site 25
S245
D
S
S
Q
S
M
E
S
L
Y
G
P
G
S
E
Site 26
Y247
S
Q
S
M
E
S
L
Y
G
P
G
S
E
G
T
Site 27
S251
E
S
L
Y
G
P
G
S
E
G
T
P
P
S
L
Site 28
T254
Y
G
P
G
S
E
G
T
P
P
S
L
E
D
C
Site 29
S257
G
S
E
G
T
P
P
S
L
E
D
C
D
A
G
Site 30
Y295
Y
A
K
N
M
A
K
Y
M
K
D
L
I
S
Y
Site 31
S301
K
Y
M
K
D
L
I
S
Y
L
E
K
R
T
T
Site 32
Y302
Y
M
K
D
L
I
S
Y
L
E
K
R
T
T
L
Site 33
T308
S
Y
L
E
K
R
T
T
L
E
M
E
F
A
K
Site 34
S353
Q
D
L
E
F
G
H
S
M
V
Q
A
V
G
T
Site 35
T371
Q
T
F
M
Q
P
L
T
L
R
R
L
E
H
E
Site 36
S400
R
K
L
Q
E
A
E
S
N
L
R
K
A
K
Q
Site 37
Y409
L
R
K
A
K
Q
G
Y
V
Q
R
C
E
D
H
Site 38
S433
A
E
E
E
Q
A
G
S
A
P
G
A
G
S
T
Site 39
S439
G
S
A
P
G
A
G
S
T
A
T
K
T
L
D
Site 40
T440
S
A
P
G
A
G
S
T
A
T
K
T
L
D
K
Site 41
T444
A
G
S
T
A
T
K
T
L
D
K
R
R
R
L
Site 42
T465
K
A
E
E
A
M
A
T
Y
R
T
C
V
A
D
Site 43
Y466
A
E
E
A
M
A
T
Y
R
T
C
V
A
D
A
Site 44
T475
T
C
V
A
D
A
K
T
Q
K
Q
E
L
E
D
Site 45
T483
Q
K
Q
E
L
E
D
T
K
V
T
A
L
R
Q
Site 46
S498
I
Q
E
V
I
R
Q
S
D
Q
T
I
K
S
A
Site 47
T501
V
I
R
Q
S
D
Q
T
I
K
S
A
T
I
S
Site 48
S504
Q
S
D
Q
T
I
K
S
A
T
I
S
Y
Y
Q
Site 49
Y510
K
S
A
T
I
S
Y
Y
Q
M
M
H
M
Q
T
Site 50
Y534
L
C
E
S
S
K
L
Y
D
P
G
Q
Q
Y
A
Site 51
Y540
L
Y
D
P
G
Q
Q
Y
A
S
H
V
R
Q
L
Site 52
S542
D
P
G
Q
Q
Y
A
S
H
V
R
Q
L
Q
R
Site 53
Y557
D
Q
E
P
D
V
H
Y
D
F
E
P
H
V
S
Site 54
S564
Y
D
F
E
P
H
V
S
A
N
A
W
S
P
V
Site 55
S569
H
V
S
A
N
A
W
S
P
V
M
R
A
R
K
Site 56
S577
P
V
M
R
A
R
K
S
S
F
N
V
S
D
V
Site 57
S578
V
M
R
A
R
K
S
S
F
N
V
S
D
V
A
Site 58
S582
R
K
S
S
F
N
V
S
D
V
A
R
P
E
A
Site 59
S592
A
R
P
E
A
A
G
S
P
P
E
E
G
G
C
Site 60
T600
P
P
E
E
G
G
C
T
E
G
T
P
A
K
D
Site 61
T603
E
G
G
C
T
E
G
T
P
A
K
D
H
R
A
Site 62
S619
R
G
H
Q
V
H
K
S
W
P
L
S
I
S
D
Site 63
S623
V
H
K
S
W
P
L
S
I
S
D
S
D
S
G
Site 64
S625
K
S
W
P
L
S
I
S
D
S
D
S
G
L
D
Site 65
S627
W
P
L
S
I
S
D
S
D
S
G
L
D
P
G
Site 66
S629
L
S
I
S
D
S
D
S
G
L
D
P
G
P
G
Site 67
S647
F
K
K
F
E
R
T
S
S
S
G
T
M
S
S
Site 68
S648
K
K
F
E
R
T
S
S
S
G
T
M
S
S
T
Site 69
S649
K
F
E
R
T
S
S
S
G
T
M
S
S
T
E
Site 70
T651
E
R
T
S
S
S
G
T
M
S
S
T
E
E
L
Site 71
S653
T
S
S
S
G
T
M
S
S
T
E
E
L
V
D
Site 72
S654
S
S
S
G
T
M
S
S
T
E
E
L
V
D
P
Site 73
T679
Q
A
D
L
N
G
M
T
P
E
L
P
V
A
V
Site 74
S688
E
L
P
V
A
V
P
S
G
P
F
R
H
E
G
Site 75
S697
P
F
R
H
E
G
L
S
K
A
A
R
T
H
R
Site 76
T710
H
R
L
R
K
L
R
T
P
A
K
C
R
E
C
Site 77
Y720
K
C
R
E
C
N
S
Y
V
Y
F
Q
G
A
E
Site 78
Y722
R
E
C
N
S
Y
V
Y
F
Q
G
A
E
C
E
Site 79
S764
Q
L
F
G
Q
D
F
S
H
A
A
R
S
A
P
Site 80
S769
D
F
S
H
A
A
R
S
A
P
D
G
V
P
F
Site 81
Y796
A
L
R
T
K
G
I
Y
R
V
N
G
V
K
T
Site 82
T803
Y
R
V
N
G
V
K
T
R
V
E
K
L
C
Q
Site 83
S822
G
K
E
L
V
E
L
S
Q
A
S
P
H
D
I
Site 84
S825
L
V
E
L
S
Q
A
S
P
H
D
I
S
N
V
Site 85
S830
Q
A
S
P
H
D
I
S
N
V
L
K
L
Y
L
Site 86
Y836
I
S
N
V
L
K
L
Y
L
R
Q
L
P
E
P
Site 87
S846
Q
L
P
E
P
L
I
S
F
R
L
Y
H
E
L
Site 88
S880
G
R
Q
D
G
S
E
S
E
A
V
A
V
A
L
Site 89
S905
L
P
P
E
N
R
A
S
L
Q
Y
L
L
R
H
Site 90
Y908
E
N
R
A
S
L
Q
Y
L
L
R
H
L
R
R
Site 91
T926
V
E
Q
D
N
K
M
T
P
G
N
L
G
I
V
Site 92
T944
T
L
L
R
P
R
P
T
E
A
T
V
S
L
S
Site 93
T947
R
P
R
P
T
E
A
T
V
S
L
S
S
L
V
Site 94
S949
R
P
T
E
A
T
V
S
L
S
S
L
V
D
Y
Site 95
S952
E
A
T
V
S
L
S
S
L
V
D
Y
P
H
Q
Site 96
Y956
S
L
S
S
L
V
D
Y
P
H
Q
A
R
V
I
Site 97
T981
F
E
E
E
P
E
E
T
P
G
G
Q
D
E
S
Site 98
S989
P
G
G
Q
D
E
S
S
N
Q
R
A
E
V
V
Site 99
S1023
A
A
D
G
C
R
E
S
R
V
V
S
N
D
S
Site 100
S1027
C
R
E
S
R
V
V
S
N
D
S
D
S
D
L
Site 101
S1030
S
R
V
V
S
N
D
S
D
S
D
L
E
E
A
Site 102
S1032
V
V
S
N
D
S
D
S
D
L
E
E
A
S
E
Site 103
S1038
D
S
D
L
E
E
A
S
E
L
L
S
S
S
E
Site 104
S1042
E
E
A
S
E
L
L
S
S
S
E
A
S
A
L
Site 105
S1043
E
A
S
E
L
L
S
S
S
E
A
S
A
L
G
Site 106
S1044
A
S
E
L
L
S
S
S
E
A
S
A
L
G
H
Site 107
S1053
A
S
A
L
G
H
L
S
F
L
E
Q
Q
Q
S
Site 108
S1060
S
F
L
E
Q
Q
Q
S
E
A
S
L
E
V
A
Site 109
S1063
E
Q
Q
Q
S
E
A
S
L
E
V
A
S
G
S
Site 110
S1068
E
A
S
L
E
V
A
S
G
S
H
S
G
S
E
Site 111
S1070
S
L
E
V
A
S
G
S
H
S
G
S
E
E
Q
Site 112
S1072
E
V
A
S
G
S
H
S
G
S
E
E
Q
L
E
Site 113
S1074
A
S
G
S
H
S
G
S
E
E
Q
L
E
A
T
Site 114
S1098
D
G
P
A
Q
Q
L
S
G
F
N
T
N
Q
S
Site 115
T1102
Q
Q
L
S
G
F
N
T
N
Q
S
N
N
V
L
Site 116
T1124
R
L
R
G
G
R
M
T
L
G
S
C
R
E
R
Site 117
S1127
G
G
R
M
T
L
G
S
C
R
E
R
Q
P
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation