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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NUP205
Full Name:
Nuclear pore complex protein Nup205
Alias:
205 kDa nucleoporin; C7orf14; KIAA0225; NU205; Nucleoporin 205kDa; Nucleoporin Nup205
Type:
Nucleoporin
Mass (Da):
227921
Number AA:
2012
UniProt ID:
Q92621
International Prot ID:
IPI00783781
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005643
GO:0005635
GO:0005643
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0051028
GO:0000059
GO:0055085
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T3
_
_
_
_
_
M
A
T
P
L
A
V
N
S
A
Site 2
S12
L
A
V
N
S
A
A
S
L
W
G
P
Y
K
D
Site 3
S52
K
H
K
P
D
F
I
S
L
F
K
N
P
P
K
Site 4
S145
G
K
R
C
I
A
N
S
L
K
A
L
I
Q
S
Site 5
S152
S
L
K
A
L
I
Q
S
R
R
G
K
T
W
T
Site 6
T157
I
Q
S
R
R
G
K
T
W
T
L
E
L
S
P
Site 7
T159
S
R
R
G
K
T
W
T
L
E
L
S
P
E
L
Site 8
S163
K
T
W
T
L
E
L
S
P
E
L
A
S
M
T
Site 9
T170
S
P
E
L
A
S
M
T
T
R
F
T
D
E
L
Site 10
T174
A
S
M
T
T
R
F
T
D
E
L
M
E
Q
G
Site 11
S218
E
K
H
R
K
E
V
S
D
L
I
K
E
C
R
Site 12
S239
L
F
A
W
A
C
Q
S
P
L
G
K
E
D
T
Site 13
S287
D
I
S
F
I
E
Q
S
T
E
E
R
D
D
M
Site 14
Y306
P
L
L
T
E
K
Q
Y
I
A
T
I
H
S
R
Site 15
S317
I
H
S
R
L
Q
D
S
Q
L
W
K
L
P
G
Site 16
T328
K
L
P
G
L
Q
A
T
V
R
L
A
W
A
L
Site 17
S379
L
M
E
S
V
V
V
S
E
Y
F
Y
Q
E
E
Site 18
Y381
E
S
V
V
V
S
E
Y
F
Y
Q
E
E
F
Y
Site 19
Y383
V
V
V
S
E
Y
F
Y
Q
E
E
F
Y
I
R
Site 20
Y388
Y
F
Y
Q
E
E
F
Y
I
R
R
V
H
N
L
Site 21
S434
M
G
N
E
P
P
I
S
L
R
R
D
L
E
H
Site 22
Y450
M
L
L
I
G
E
L
Y
K
K
N
P
F
H
L
Site 23
Y463
H
L
E
L
A
L
E
Y
W
C
P
T
E
P
L
Site 24
T472
C
P
T
E
P
L
Q
T
P
T
I
M
G
S
Y
Site 25
T474
T
E
P
L
Q
T
P
T
I
M
G
S
Y
L
G
Site 26
S495
P
Q
R
Q
V
V
L
S
K
F
V
R
Q
M
G
Site 27
S539
S
L
L
K
V
N
G
S
S
H
V
E
N
I
Q
Site 28
S551
N
I
Q
G
A
G
G
S
P
V
S
W
E
H
F
Site 29
S554
G
A
G
G
S
P
V
S
W
E
H
F
F
H
S
Site 30
Y565
F
F
H
S
L
M
L
Y
H
E
H
L
R
K
D
Site 31
S575
H
L
R
K
D
L
P
S
A
D
S
V
Q
Y
R
Site 32
S578
K
D
L
P
S
A
D
S
V
Q
Y
R
H
L
P
Site 33
Y581
P
S
A
D
S
V
Q
Y
R
H
L
P
S
R
G
Site 34
T590
H
L
P
S
R
G
I
T
Q
K
E
Q
D
G
L
Site 35
T609
Q
L
T
S
T
I
I
T
W
S
E
N
A
R
L
Site 36
S662
K
S
P
E
I
A
A
S
L
W
Q
S
L
E
Y
Site 37
T670
L
W
Q
S
L
E
Y
T
Q
I
L
Q
T
V
R
Site 38
T675
E
Y
T
Q
I
L
Q
T
V
R
I
P
S
Q
R
Site 39
S680
L
Q
T
V
R
I
P
S
Q
R
Q
A
I
G
I
Site 40
S696
V
E
L
N
E
I
E
S
R
C
E
E
Y
P
L
Site 41
Y701
I
E
S
R
C
E
E
Y
P
L
T
R
A
F
C
Site 42
Y735
R
P
P
G
F
D
P
Y
L
Q
F
L
R
D
S
Site 43
S742
Y
L
Q
F
L
R
D
S
V
F
L
R
F
R
T
Site 44
T749
S
V
F
L
R
F
R
T
R
A
Y
R
R
A
A
Site 45
Y752
L
R
F
R
T
R
A
Y
R
R
A
A
E
K
W
Site 46
Y776
F
Y
K
L
L
R
D
Y
E
P
Q
L
E
D
F
Site 47
Y798
Q
G
E
E
I
I
A
Y
K
P
P
G
F
S
L
Site 48
Y807
P
P
G
F
S
L
M
Y
H
L
L
N
E
S
P
Site 49
T832
E
G
V
K
Q
L
D
T
Y
A
P
F
P
G
K
Site 50
Y833
G
V
K
Q
L
D
T
Y
A
P
F
P
G
K
K
Site 51
Y902
N
V
V
N
I
A
R
Y
L
Y
H
G
N
T
N
Site 52
Y904
V
N
I
A
R
Y
L
Y
H
G
N
T
N
P
E
Site 53
T938
I
K
L
V
G
D
F
T
H
D
Q
S
I
S
Q
Site 54
S942
G
D
F
T
H
D
Q
S
I
S
Q
K
L
M
A
Site 55
S944
F
T
H
D
Q
S
I
S
Q
K
L
M
A
G
F
Site 56
S970
F
V
R
L
E
E
G
S
E
L
E
K
K
L
V
Site 57
S1016
F
E
L
K
K
P
V
S
T
T
N
L
Q
D
P
Site 58
T1076
Q
L
C
A
C
S
D
T
S
G
P
T
M
R
Y
Site 59
Y1083
T
S
G
P
T
M
R
Y
L
R
T
S
Q
D
F
Site 60
T1086
P
T
M
R
Y
L
R
T
S
Q
D
F
L
F
S
Site 61
S1087
T
M
R
Y
L
R
T
S
Q
D
F
L
F
S
Q
Site 62
S1093
T
S
Q
D
F
L
F
S
Q
L
Q
Y
L
P
F
Site 63
Y1097
F
L
F
S
Q
L
Q
Y
L
P
F
S
N
K
E
Site 64
S1101
Q
L
Q
Y
L
P
F
S
N
K
E
Y
E
I
S
Site 65
Y1105
L
P
F
S
N
K
E
Y
E
I
S
M
L
N
Q
Site 66
T1127
A
S
I
E
L
R
V
T
S
L
N
R
Q
R
S
Site 67
S1128
S
I
E
L
R
V
T
S
L
N
R
Q
R
S
H
Site 68
S1134
T
S
L
N
R
Q
R
S
H
T
Q
R
L
L
H
Site 69
T1136
L
N
R
Q
R
S
H
T
Q
R
L
L
H
L
L
Site 70
Y1152
D
D
M
P
V
K
P
Y
S
D
G
E
G
G
I
Site 71
S1153
D
M
P
V
K
P
Y
S
D
G
E
G
G
I
E
Site 72
S1165
G
I
E
D
E
N
R
S
V
S
G
F
L
H
F
Site 73
S1167
E
D
E
N
R
S
V
S
G
F
L
H
F
D
T
Site 74
T1174
S
G
F
L
H
F
D
T
A
T
K
V
R
R
K
Site 75
T1176
F
L
H
F
D
T
A
T
K
V
R
R
K
I
L
Site 76
S1192
I
L
D
S
I
D
F
S
Q
E
I
P
E
P
L
Site 77
T1225
H
K
N
L
R
G
Q
T
V
C
N
V
K
L
L
Site 78
S1285
A
K
R
H
A
L
E
S
W
R
Q
L
V
E
I
Site 79
T1357
V
L
T
E
Q
K
Q
T
S
V
L
G
P
A
E
Site 80
S1377
M
L
D
S
C
F
T
S
P
P
P
E
E
N
P
Site 81
T1419
G
G
F
Q
R
V
R
T
H
L
Y
G
S
L
L
Site 82
Y1422
Q
R
V
R
T
H
L
Y
G
S
L
L
Y
Y
L
Site 83
T1440
Q
R
P
D
E
P
D
T
L
E
A
A
K
K
T
Site 84
T1453
K
T
M
W
E
R
L
T
A
P
E
D
V
F
S
Site 85
S1460
T
A
P
E
D
V
F
S
K
L
Q
R
E
N
I
Site 86
S1505
A
L
L
D
R
I
V
S
V
D
K
Q
Q
Q
W
Site 87
Y1515
K
Q
Q
Q
W
L
L
Y
L
S
N
S
G
Y
L
Site 88
S1517
Q
Q
W
L
L
Y
L
S
N
S
G
Y
L
K
V
Site 89
S1528
Y
L
K
V
L
V
D
S
L
V
E
D
D
R
T
Site 90
T1535
S
L
V
E
D
D
R
T
L
Q
S
L
L
T
P
Site 91
S1538
E
D
D
R
T
L
Q
S
L
L
T
P
Q
P
P
Site 92
T1541
R
T
L
Q
S
L
L
T
P
Q
P
P
L
L
K
Site 93
Y1551
P
P
L
L
K
A
L
Y
T
Y
E
S
K
M
A
Site 94
S1555
K
A
L
Y
T
Y
E
S
K
M
A
F
L
T
R
Site 95
Y1588
R
L
A
Q
C
Q
V
Y
D
M
R
P
E
T
D
Site 96
T1594
V
Y
D
M
R
P
E
T
D
P
Q
S
M
F
G
Site 97
S1598
R
P
E
T
D
P
Q
S
M
F
G
M
R
D
P
Site 98
T1611
D
P
P
M
F
I
P
T
P
V
D
R
Y
R
Q
Site 99
Y1616
I
P
T
P
V
D
R
Y
R
Q
I
L
L
P
A
Site 100
S1700
D
V
D
V
N
E
G
S
L
M
E
L
Q
G
H
Site 101
S1720
R
Q
C
L
G
L
L
S
R
F
G
G
S
D
R
Site 102
S1725
L
L
S
R
F
G
G
S
D
R
L
R
Q
F
K
Site 103
S1744
N
V
E
G
D
K
V
S
K
K
D
E
I
E
L
Site 104
S1766
N
V
M
E
Y
C
Q
S
L
M
L
Q
S
S
P
Site 105
S1771
C
Q
S
L
M
L
Q
S
S
P
T
F
Q
H
A
Site 106
S1772
Q
S
L
M
L
Q
S
S
P
T
F
Q
H
A
V
Site 107
S1787
C
L
F
T
P
S
L
S
E
T
V
N
R
D
G
Site 108
T1789
F
T
P
S
L
S
E
T
V
N
R
D
G
P
R
Site 109
T1799
R
D
G
P
R
Q
D
T
Q
A
P
V
V
P
Y
Site 110
S1828
Q
S
A
N
D
F
F
S
Y
Y
D
S
H
R
Q
Site 111
Y1829
S
A
N
D
F
F
S
Y
Y
D
S
H
R
Q
S
Site 112
Y1830
A
N
D
F
F
S
Y
Y
D
S
H
R
Q
S
V
Site 113
S1832
D
F
F
S
Y
Y
D
S
H
R
Q
S
V
S
K
Site 114
S1836
Y
Y
D
S
H
R
Q
S
V
S
K
L
Q
N
V
Site 115
S1867
P
A
G
V
D
K
I
S
T
A
Q
K
Y
V
L
Site 116
T1868
A
G
V
D
K
I
S
T
A
Q
K
Y
V
L
A
Site 117
Y1872
K
I
S
T
A
Q
K
Y
V
L
A
R
R
R
L
Site 118
T1918
Y
L
L
H
C
M
P
T
D
S
Q
D
S
L
F
Site 119
S1920
L
H
C
M
P
T
D
S
Q
D
S
L
F
A
S
Site 120
S1923
M
P
T
D
S
Q
D
S
L
F
A
S
R
T
L
Site 121
S1927
S
Q
D
S
L
F
A
S
R
T
L
F
K
S
R
Site 122
T1929
D
S
L
F
A
S
R
T
L
F
K
S
R
R
L
Site 123
S1933
A
S
R
T
L
F
K
S
R
R
L
Q
D
S
F
Site 124
S1939
K
S
R
R
L
Q
D
S
F
A
S
E
T
N
L
Site 125
S1942
R
L
Q
D
S
F
A
S
E
T
N
L
D
F
R
Site 126
T1944
Q
D
S
F
A
S
E
T
N
L
D
F
R
S
G
Site 127
S1950
E
T
N
L
D
F
R
S
G
L
A
I
V
S
Q
Site 128
S1956
R
S
G
L
A
I
V
S
Q
H
D
L
D
Q
L
Site 129
S1974
A
I
N
A
F
G
E
S
L
Q
K
K
L
L
D
Site 130
Y1986
L
L
D
I
E
G
L
Y
S
K
V
R
S
R
Y
Site 131
S1987
L
D
I
E
G
L
Y
S
K
V
R
S
R
Y
S
Site 132
S1991
G
L
Y
S
K
V
R
S
R
Y
S
F
I
Q
A
Site 133
Y1993
Y
S
K
V
R
S
R
Y
S
F
I
Q
A
L
V
Site 134
S1994
S
K
V
R
S
R
Y
S
F
I
Q
A
L
V
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation