KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
ANKS1A
Full Name:
Ankyrin repeat and SAM domain-containing protein 1A
Alias:
ANKS1; Ankyrin repeat and SAM domain containing protein 1; Ankyrin repeat and sterile alpha motif domain containing 1A; ANS1; KIAA0229; Odin
Type:
Unknown function
Mass (Da):
123108
Number AA:
1134
UniProt ID:
Q92625
International Prot ID:
IPI00395663
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S24
P
A
V
E
K
L
L
S
G
K
R
L
S
S
G
Site 2
S29
L
L
S
G
K
R
L
S
S
G
F
G
G
G
G
Site 3
S30
L
S
G
K
R
L
S
S
G
F
G
G
G
G
G
Site 4
S40
G
G
G
G
G
G
G
S
G
G
G
G
G
G
S
Site 5
S47
S
G
G
G
G
G
G
S
G
G
G
G
G
G
L
Site 6
S56
G
G
G
G
G
L
G
S
S
S
H
P
L
S
S
Site 7
S57
G
G
G
G
L
G
S
S
S
H
P
L
S
S
L
Site 8
S62
G
S
S
S
H
P
L
S
S
L
L
S
M
W
R
Site 9
S63
S
S
S
H
P
L
S
S
L
L
S
M
W
R
G
Site 10
S66
H
P
L
S
S
L
L
S
M
W
R
G
P
N
V
Site 11
T106
L
L
R
N
D
A
L
T
N
V
A
D
S
K
G
Site 12
S111
A
L
T
N
V
A
D
S
K
G
C
Y
P
L
H
Site 13
T176
L
E
E
L
T
D
P
T
M
R
N
N
K
F
E
Site 14
T184
M
R
N
N
K
F
E
T
P
L
D
L
A
A
L
Site 15
T217
S
C
N
T
K
K
H
T
P
L
H
L
A
A
R
Site 16
S241
L
L
D
A
G
M
D
S
N
Y
Q
T
E
M
G
Site 17
Y243
D
A
G
M
D
S
N
Y
Q
T
E
M
G
S
A
Site 18
T245
G
M
D
S
N
Y
Q
T
E
M
G
S
A
L
H
Site 19
T286
H
G
L
T
A
L
D
T
V
R
E
L
P
S
Q
Site 20
S292
D
T
V
R
E
L
P
S
Q
K
S
Q
Q
I
A
Site 21
S295
R
E
L
P
S
Q
K
S
Q
Q
I
A
A
L
I
Site 22
T307
A
L
I
E
D
H
M
T
G
K
R
S
T
K
E
Site 23
T312
H
M
T
G
K
R
S
T
K
E
V
D
K
T
P
Site 24
T318
S
T
K
E
V
D
K
T
P
P
P
Q
P
P
L
Site 25
S327
P
P
Q
P
P
L
I
S
S
M
D
S
I
S
Q
Site 26
S328
P
Q
P
P
L
I
S
S
M
D
S
I
S
Q
K
Site 27
S331
P
L
I
S
S
M
D
S
I
S
Q
K
S
Q
G
Site 28
S333
I
S
S
M
D
S
I
S
Q
K
S
Q
G
D
V
Site 29
S336
M
D
S
I
S
Q
K
S
Q
G
D
V
E
K
A
Site 30
Y361
N
A
E
E
E
G
P
Y
E
A
L
Y
N
A
I
Site 31
Y365
E
G
P
Y
E
A
L
Y
N
A
I
S
C
H
S
Site 32
S369
E
A
L
Y
N
A
I
S
C
H
S
L
D
S
M
Site 33
S372
Y
N
A
I
S
C
H
S
L
D
S
M
A
S
G
Site 34
S375
I
S
C
H
S
L
D
S
M
A
S
G
R
S
S
Site 35
S378
H
S
L
D
S
M
A
S
G
R
S
S
D
Q
D
Site 36
S382
S
M
A
S
G
R
S
S
D
Q
D
S
T
N
K
Site 37
S386
G
R
S
S
D
Q
D
S
T
N
K
E
A
E
A
Site 38
Y427
E
D
H
I
D
K
K
Y
F
P
L
T
A
S
E
Site 39
T431
D
K
K
Y
F
P
L
T
A
S
E
V
L
S
M
Site 40
S433
K
Y
F
P
L
T
A
S
E
V
L
S
M
R
P
Site 41
S437
L
T
A
S
E
V
L
S
M
R
P
R
I
H
G
Site 42
S445
M
R
P
R
I
H
G
S
A
A
R
E
E
D
E
Site 43
Y455
R
E
E
D
E
H
P
Y
E
L
L
L
T
A
E
Site 44
T460
H
P
Y
E
L
L
L
T
A
E
T
K
K
V
V
Site 45
T473
V
V
L
V
D
G
K
T
K
D
H
R
R
S
S
Site 46
S479
K
T
K
D
H
R
R
S
S
S
S
R
S
Q
D
Site 47
S480
T
K
D
H
R
R
S
S
S
S
R
S
Q
D
S
Site 48
S481
K
D
H
R
R
S
S
S
S
R
S
Q
D
S
A
Site 49
S482
D
H
R
R
S
S
S
S
R
S
Q
D
S
A
E
Site 50
S484
R
R
S
S
S
S
R
S
Q
D
S
A
E
G
Q
Site 51
S487
S
S
S
R
S
Q
D
S
A
E
G
Q
D
G
Q
Site 52
T522
D
P
F
Q
L
L
C
T
A
G
Q
S
H
P
D
Site 53
S526
L
L
C
T
A
G
Q
S
H
P
D
G
S
P
Q
Site 54
S531
G
Q
S
H
P
D
G
S
P
Q
Q
G
A
C
H
Site 55
S555
G
V
H
A
P
G
A
S
Q
P
S
A
L
D
Q
Site 56
S563
Q
P
S
A
L
D
Q
S
K
R
V
G
Y
L
T
Site 57
Y568
D
Q
S
K
R
V
G
Y
L
T
G
L
P
T
T
Site 58
T570
S
K
R
V
G
Y
L
T
G
L
P
T
T
N
S
Site 59
T574
G
Y
L
T
G
L
P
T
T
N
S
R
S
H
P
Site 60
T575
Y
L
T
G
L
P
T
T
N
S
R
S
H
P
E
Site 61
S577
T
G
L
P
T
T
N
S
R
S
H
P
E
T
L
Site 62
S579
L
P
T
T
N
S
R
S
H
P
E
T
L
T
H
Site 63
T583
N
S
R
S
H
P
E
T
L
T
H
T
A
S
P
Site 64
T585
R
S
H
P
E
T
L
T
H
T
A
S
P
H
P
Site 65
T587
H
P
E
T
L
T
H
T
A
S
P
H
P
G
G
Site 66
S589
E
T
L
T
H
T
A
S
P
H
P
G
G
A
E
Site 67
S601
G
A
E
E
G
D
R
S
G
A
R
S
R
A
P
Site 68
S605
G
D
R
S
G
A
R
S
R
A
P
P
T
S
K
Site 69
T610
A
R
S
R
A
P
P
T
S
K
P
K
A
E
L
Site 70
S611
R
S
R
A
P
P
T
S
K
P
K
A
E
L
K
Site 71
S620
P
K
A
E
L
K
L
S
R
S
L
S
K
S
D
Site 72
S622
A
E
L
K
L
S
R
S
L
S
K
S
D
S
D
Site 73
S624
L
K
L
S
R
S
L
S
K
S
D
S
D
L
L
Site 74
S626
L
S
R
S
L
S
K
S
D
S
D
L
L
T
C
Site 75
S628
R
S
L
S
K
S
D
S
D
L
L
T
C
S
P
Site 76
T632
K
S
D
S
D
L
L
T
C
S
P
T
E
D
A
Site 77
S634
D
S
D
L
L
T
C
S
P
T
E
D
A
T
M
Site 78
T640
C
S
P
T
E
D
A
T
M
G
S
R
S
E
S
Site 79
S643
T
E
D
A
T
M
G
S
R
S
E
S
L
S
N
Site 80
S645
D
A
T
M
G
S
R
S
E
S
L
S
N
C
S
Site 81
S647
T
M
G
S
R
S
E
S
L
S
N
C
S
I
G
Site 82
S649
G
S
R
S
E
S
L
S
N
C
S
I
G
K
K
Site 83
S652
S
E
S
L
S
N
C
S
I
G
K
K
R
L
E
Site 84
S661
G
K
K
R
L
E
K
S
P
S
F
A
S
E
W
Site 85
S663
K
R
L
E
K
S
P
S
F
A
S
E
W
D
E
Site 86
S666
E
K
S
P
S
F
A
S
E
W
D
E
I
E
K
Site 87
S676
D
E
I
E
K
I
M
S
S
I
G
E
G
I
D
Site 88
S677
E
I
E
K
I
M
S
S
I
G
E
G
I
D
F
Site 89
S685
I
G
E
G
I
D
F
S
Q
E
R
Q
K
I
S
Site 90
S692
S
Q
E
R
Q
K
I
S
G
L
R
T
L
E
Q
Site 91
T696
Q
K
I
S
G
L
R
T
L
E
Q
S
V
G
E
Site 92
S700
G
L
R
T
L
E
Q
S
V
G
E
W
L
E
S
Site 93
S707
S
V
G
E
W
L
E
S
I
G
L
Q
Q
Y
E
Site 94
Y713
E
S
I
G
L
Q
Q
Y
E
S
K
L
L
L
N
Site 95
S744
D
L
R
D
I
G
I
S
D
P
Q
H
R
R
K
Site 96
Y767
P
K
V
K
A
L
G
Y
D
G
N
S
P
P
S
Site 97
S771
A
L
G
Y
D
G
N
S
P
P
S
V
P
S
W
Site 98
S774
Y
D
G
N
S
P
P
S
V
P
S
W
L
D
S
Site 99
S777
N
S
P
P
S
V
P
S
W
L
D
S
L
G
L
Site 100
S781
S
V
P
S
W
L
D
S
L
G
L
Q
D
Y
V
Site 101
Y787
D
S
L
G
L
Q
D
Y
V
H
S
F
L
S
S
Site 102
S790
G
L
Q
D
Y
V
H
S
F
L
S
S
G
Y
S
Site 103
S793
D
Y
V
H
S
F
L
S
S
G
Y
S
S
I
D
Site 104
S794
Y
V
H
S
F
L
S
S
G
Y
S
S
I
D
T
Site 105
S797
S
F
L
S
S
G
Y
S
S
I
D
T
V
K
N
Site 106
S798
F
L
S
S
G
Y
S
S
I
D
T
V
K
N
L
Site 107
T801
S
G
Y
S
S
I
D
T
V
K
N
L
W
E
L
Site 108
S828
H
R
K
R
I
I
A
S
L
A
D
R
P
Y
E
Site 109
Y834
A
S
L
A
D
R
P
Y
E
E
P
P
Q
K
P
Site 110
S845
P
Q
K
P
P
R
F
S
Q
L
R
C
Q
D
L
Site 111
S854
L
R
C
Q
D
L
L
S
Q
T
S
S
P
L
S
Site 112
T856
C
Q
D
L
L
S
Q
T
S
S
P
L
S
Q
N
Site 113
S857
Q
D
L
L
S
Q
T
S
S
P
L
S
Q
N
D
Site 114
S858
D
L
L
S
Q
T
S
S
P
L
S
Q
N
D
S
Site 115
S861
S
Q
T
S
S
P
L
S
Q
N
D
S
C
T
G
Site 116
S865
S
P
L
S
Q
N
D
S
C
T
G
R
S
A
D
Site 117
T867
L
S
Q
N
D
S
C
T
G
R
S
A
D
L
L
Site 118
T880
L
L
L
P
P
G
D
T
G
R
R
R
H
D
S
Site 119
S887
T
G
R
R
R
H
D
S
L
H
D
P
A
A
P
Site 120
T912
E
H
R
E
A
K
L
T
L
R
P
P
S
L
A
Site 121
S917
K
L
T
L
R
P
P
S
L
A
A
P
Y
A
P
Site 122
Y922
P
P
S
L
A
A
P
Y
A
P
V
Q
S
W
Q
Site 123
T958
L
I
K
D
L
R
G
T
E
S
T
Q
D
A
C
Site 124
S960
K
D
L
R
G
T
E
S
T
Q
D
A
C
A
K
Site 125
T961
D
L
R
G
T
E
S
T
Q
D
A
C
A
K
M
Site 126
T972
C
A
K
M
R
K
S
T
E
H
M
K
K
I
P
Site 127
S1010
E
H
E
I
R
N
I
S
C
A
A
Q
D
P
E
Site 128
T1021
Q
D
P
E
D
L
C
T
F
A
Y
I
T
K
D
Site 129
Y1024
E
D
L
C
T
F
A
Y
I
T
K
D
L
Q
T
Site 130
Y1035
D
L
Q
T
S
H
H
Y
C
H
V
F
S
T
V
Site 131
S1071
L
A
L
Q
A
Q
K
S
R
A
T
G
A
S
A
Site 132
T1074
Q
A
Q
K
S
R
A
T
G
A
S
A
A
E
M
Site 133
S1077
K
S
R
A
T
G
A
S
A
A
E
M
I
E
T
Site 134
T1084
S
A
A
E
M
I
E
T
K
S
S
K
P
V
P
Site 135
S1086
A
E
M
I
E
T
K
S
S
K
P
V
P
K
P
Site 136
S1087
E
M
I
E
T
K
S
S
K
P
V
P
K
P
R
Site 137
S1100
P
R
V
G
V
R
K
S
A
L
E
P
P
D
M
Site 138
S1113
D
M
D
Q
D
A
Q
S
H
A
S
V
S
W
V
Site 139
S1116
Q
D
A
Q
S
H
A
S
V
S
W
V
V
D
P
Site 140
S1118
A
Q
S
H
A
S
V
S
W
V
V
D
P
K
P
Site 141
S1127
V
V
D
P
K
P
D
S
K
R
S
L
S
T
N
Site 142
S1130
P
K
P
D
S
K
R
S
L
S
T
N
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation