KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
KIAA0232
Full Name:
Uncharacterized protein KIAA0232
Alias:
K0232; LOC9778
Type:
Unknown function
Mass (Da):
154803
Number AA:
1395
UniProt ID:
Q92628
International Prot ID:
IPI00294215
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0000166
GO:0005488
GO:0005524
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S14
V
V
V
D
G
L
P
S
E
S
S
S
S
S
Y
Site 2
S16
V
D
G
L
P
S
E
S
S
S
S
S
Y
P
G
Site 3
S17
D
G
L
P
S
E
S
S
S
S
S
Y
P
G
P
Site 4
S18
G
L
P
S
E
S
S
S
S
S
Y
P
G
P
V
Site 5
S19
L
P
S
E
S
S
S
S
S
Y
P
G
P
V
S
Site 6
S20
P
S
E
S
S
S
S
S
Y
P
G
P
V
S
V
Site 7
Y21
S
E
S
S
S
S
S
Y
P
G
P
V
S
V
S
Site 8
S69
L
S
L
L
L
H
D
S
Y
D
Y
D
L
Q
E
Site 9
Y70
S
L
L
L
H
D
S
Y
D
Y
D
L
Q
E
Q
Site 10
Y72
L
L
H
D
S
Y
D
Y
D
L
Q
E
Q
E
N
Site 11
Y90
L
G
W
E
K
G
A
Y
K
K
W
G
K
S
K
Site 12
S96
A
Y
K
K
W
G
K
S
K
K
K
C
S
D
L
Site 13
S101
G
K
S
K
K
K
C
S
D
L
T
L
E
E
M
Site 14
T104
K
K
K
C
S
D
L
T
L
E
E
M
K
K
Q
Site 15
S119
A
A
V
Q
C
L
R
S
A
S
D
E
S
S
G
Site 16
S121
V
Q
C
L
R
S
A
S
D
E
S
S
G
I
E
Site 17
S125
R
S
A
S
D
E
S
S
G
I
E
T
L
V
E
Site 18
T129
D
E
S
S
G
I
E
T
L
V
E
E
L
C
S
Site 19
S136
T
L
V
E
E
L
C
S
R
L
K
D
L
Q
S
Site 20
S143
S
R
L
K
D
L
Q
S
K
Q
E
E
K
I
H
Site 21
S156
I
H
K
K
L
E
G
S
P
S
P
E
A
E
L
Site 22
S158
K
K
L
E
G
S
P
S
P
E
A
E
L
S
P
Site 23
S164
P
S
P
E
A
E
L
S
P
P
A
K
D
Q
V
Site 24
Y174
A
K
D
Q
V
E
M
Y
Y
E
A
F
P
P
L
Site 25
Y175
K
D
Q
V
E
M
Y
Y
E
A
F
P
P
L
S
Site 26
S182
Y
E
A
F
P
P
L
S
E
K
P
V
C
L
Q
Site 27
S202
W
N
K
S
K
V
C
S
Y
S
S
S
S
S
S
Site 28
Y203
N
K
S
K
V
C
S
Y
S
S
S
S
S
S
S
Site 29
S204
K
S
K
V
C
S
Y
S
S
S
S
S
S
S
T
Site 30
S205
S
K
V
C
S
Y
S
S
S
S
S
S
S
T
A
Site 31
S206
K
V
C
S
Y
S
S
S
S
S
S
S
T
A
P
Site 32
S207
V
C
S
Y
S
S
S
S
S
S
S
T
A
P
P
Site 33
S208
C
S
Y
S
S
S
S
S
S
S
T
A
P
P
A
Site 34
S209
S
Y
S
S
S
S
S
S
S
T
A
P
P
A
S
Site 35
S210
Y
S
S
S
S
S
S
S
T
A
P
P
A
S
T
Site 36
T211
S
S
S
S
S
S
S
T
A
P
P
A
S
T
D
Site 37
S216
S
S
T
A
P
P
A
S
T
D
T
S
S
P
K
Site 38
T217
S
T
A
P
P
A
S
T
D
T
S
S
P
K
D
Site 39
T219
A
P
P
A
S
T
D
T
S
S
P
K
D
C
N
Site 40
S220
P
P
A
S
T
D
T
S
S
P
K
D
C
N
S
Site 41
S221
P
A
S
T
D
T
S
S
P
K
D
C
N
S
E
Site 42
S227
S
S
P
K
D
C
N
S
E
S
E
V
T
K
E
Site 43
S229
P
K
D
C
N
S
E
S
E
V
T
K
E
R
S
Site 44
T232
C
N
S
E
S
E
V
T
K
E
R
S
S
E
V
Site 45
S237
E
V
T
K
E
R
S
S
E
V
P
T
T
V
H
Site 46
T241
E
R
S
S
E
V
P
T
T
V
H
E
K
T
Q
Site 47
T242
R
S
S
E
V
P
T
T
V
H
E
K
T
Q
S
Site 48
T247
P
T
T
V
H
E
K
T
Q
S
K
S
K
N
E
Site 49
S249
T
V
H
E
K
T
Q
S
K
S
K
N
E
K
E
Site 50
S251
H
E
K
T
Q
S
K
S
K
N
E
K
E
N
K
Site 51
S260
N
E
K
E
N
K
F
S
N
G
T
I
E
E
K
Site 52
Y271
I
E
E
K
P
A
L
Y
K
K
Q
I
R
H
K
Site 53
S287
E
G
K
I
R
P
R
S
W
S
S
G
S
S
E
Site 54
S289
K
I
R
P
R
S
W
S
S
G
S
S
E
A
G
Site 55
S290
I
R
P
R
S
W
S
S
G
S
S
E
A
G
S
Site 56
S292
P
R
S
W
S
S
G
S
S
E
A
G
S
S
S
Site 57
S293
R
S
W
S
S
G
S
S
E
A
G
S
S
S
S
Site 58
S297
S
G
S
S
E
A
G
S
S
S
S
G
N
Q
G
Site 59
S298
G
S
S
E
A
G
S
S
S
S
G
N
Q
G
E
Site 60
S299
S
S
E
A
G
S
S
S
S
G
N
Q
G
E
L
Site 61
S309
N
Q
G
E
L
K
A
S
M
K
Y
V
K
V
R
Site 62
Y312
E
L
K
A
S
M
K
Y
V
K
V
R
H
K
A
Site 63
S332
K
K
G
R
N
G
Q
S
R
L
S
L
K
H
G
Site 64
S335
R
N
G
Q
S
R
L
S
L
K
H
G
E
K
A
Site 65
T348
K
A
E
R
N
I
H
T
G
S
S
S
S
S
S
Site 66
S350
E
R
N
I
H
T
G
S
S
S
S
S
S
S
G
Site 67
S351
R
N
I
H
T
G
S
S
S
S
S
S
S
G
S
Site 68
S352
N
I
H
T
G
S
S
S
S
S
S
S
G
S
V
Site 69
S353
I
H
T
G
S
S
S
S
S
S
S
G
S
V
K
Site 70
S354
H
T
G
S
S
S
S
S
S
S
G
S
V
K
Q
Site 71
S355
T
G
S
S
S
S
S
S
S
G
S
V
K
Q
L
Site 72
S356
G
S
S
S
S
S
S
S
G
S
V
K
Q
L
C
Site 73
S358
S
S
S
S
S
S
G
S
V
K
Q
L
C
K
R
Site 74
S380
I
G
R
K
D
P
G
S
T
E
G
K
D
L
Y
Site 75
Y387
S
T
E
G
K
D
L
Y
M
E
N
R
K
D
T
Site 76
T394
Y
M
E
N
R
K
D
T
E
Y
K
E
E
P
L
Site 77
Y396
E
N
R
K
D
T
E
Y
K
E
E
P
L
W
Y
Site 78
Y403
Y
K
E
E
P
L
W
Y
T
E
P
I
A
E
Y
Site 79
Y410
Y
T
E
P
I
A
E
Y
F
V
P
L
S
R
K
Site 80
S415
A
E
Y
F
V
P
L
S
R
K
S
K
L
E
T
Site 81
S418
F
V
P
L
S
R
K
S
K
L
E
T
T
Y
R
Site 82
T422
S
R
K
S
K
L
E
T
T
Y
R
N
R
Q
D
Site 83
T423
R
K
S
K
L
E
T
T
Y
R
N
R
Q
D
T
Site 84
T430
T
Y
R
N
R
Q
D
T
S
D
L
T
S
E
A
Site 85
S431
Y
R
N
R
Q
D
T
S
D
L
T
S
E
A
V
Site 86
T434
R
Q
D
T
S
D
L
T
S
E
A
V
E
E
L
Site 87
S435
Q
D
T
S
D
L
T
S
E
A
V
E
E
L
S
Site 88
S442
S
E
A
V
E
E
L
S
E
S
V
H
G
L
C
Site 89
T458
S
N
N
N
L
H
K
T
Y
L
A
A
G
T
F
Site 90
Y459
N
N
N
L
H
K
T
Y
L
A
A
G
T
F
I
Site 91
S487
D
I
D
L
T
G
T
S
L
C
S
L
P
E
D
Site 92
S490
L
T
G
T
S
L
C
S
L
P
E
D
N
K
Y
Site 93
Y497
S
L
P
E
D
N
K
Y
L
D
D
I
H
L
S
Site 94
S517
Y
E
V
D
I
D
Q
S
M
L
D
P
G
A
S
Site 95
S524
S
M
L
D
P
G
A
S
E
T
M
Q
G
E
S
Site 96
S541
L
K
M
I
R
Q
K
S
K
E
N
T
D
F
E
Site 97
T545
R
Q
K
S
K
E
N
T
D
F
E
A
E
C
C
Site 98
T568
Q
G
E
R
A
I
W
T
D
S
T
S
S
V
G
Site 99
S570
E
R
A
I
W
T
D
S
T
S
S
V
G
A
E
Site 100
T571
R
A
I
W
T
D
S
T
S
S
V
G
A
E
G
Site 101
S595
A
Q
F
W
E
C
C
S
S
S
S
G
D
A
D
Site 102
S596
Q
F
W
E
C
C
S
S
S
S
G
D
A
D
G
Site 103
S605
S
G
D
A
D
G
E
S
F
G
G
D
S
P
V
Site 104
S610
G
E
S
F
G
G
D
S
P
V
R
L
S
P
I
Site 105
S615
G
D
S
P
V
R
L
S
P
I
L
D
S
T
V
Site 106
S636
A
G
N
Q
E
L
F
S
D
I
N
E
G
S
G
Site 107
S642
F
S
D
I
N
E
G
S
G
I
N
S
C
F
S
Site 108
T674
L
N
L
G
N
E
N
T
D
S
S
A
N
M
L
Site 109
S676
L
G
N
E
N
T
D
S
S
A
N
M
L
G
K
Site 110
T684
S
A
N
M
L
G
K
T
Q
S
R
L
L
I
W
Site 111
S686
N
M
L
G
K
T
Q
S
R
L
L
I
W
T
K
Site 112
T692
Q
S
R
L
L
I
W
T
K
N
S
A
F
E
E
Site 113
T708
E
H
C
S
N
L
S
T
R
T
C
S
P
W
S
Site 114
T710
C
S
N
L
S
T
R
T
C
S
P
W
S
H
S
Site 115
S712
N
L
S
T
R
T
C
S
P
W
S
H
S
E
E
Site 116
S715
T
R
T
C
S
P
W
S
H
S
E
E
T
R
S
Site 117
S717
T
C
S
P
W
S
H
S
E
E
T
R
S
D
N
Site 118
S722
S
H
S
E
E
T
R
S
D
N
E
T
L
N
I
Site 119
T726
E
T
R
S
D
N
E
T
L
N
I
Q
F
E
E
Site 120
Y744
F
N
A
E
D
I
N
Y
V
V
P
R
V
S
S
Site 121
S750
N
Y
V
V
P
R
V
S
S
N
Y
V
D
E
E
Site 122
S751
Y
V
V
P
R
V
S
S
N
Y
V
D
E
E
L
Site 123
Y753
V
P
R
V
S
S
N
Y
V
D
E
E
L
L
D
Site 124
T766
L
D
F
L
Q
D
E
T
C
Q
Q
N
S
R
T
Site 125
T773
T
C
Q
Q
N
S
R
T
L
G
E
I
P
T
L
Site 126
T779
R
T
L
G
E
I
P
T
L
V
F
K
K
T
S
Site 127
T785
P
T
L
V
F
K
K
T
S
K
L
E
S
V
C
Site 128
S790
K
K
T
S
K
L
E
S
V
C
G
I
Q
L
E
Site 129
S814
T
T
Q
V
C
N
E
S
P
H
G
D
G
Y
S
Site 130
Y820
E
S
P
H
G
D
G
Y
S
S
G
V
I
K
D
Site 131
S821
S
P
H
G
D
G
Y
S
S
G
V
I
K
D
I
Site 132
T835
I
W
T
K
M
A
D
T
N
S
V
A
T
V
E
Site 133
S837
T
K
M
A
D
T
N
S
V
A
T
V
E
I
E
Site 134
T846
A
T
V
E
I
E
R
T
D
A
E
L
F
S
A
Site 135
S881
P
D
K
A
V
R
R
S
E
Y
H
L
W
E
G
Site 136
Y883
K
A
V
R
R
S
E
Y
H
L
W
E
G
Q
K
Site 137
S892
L
W
E
G
Q
K
E
S
L
E
K
R
A
F
A
Site 138
S900
L
E
K
R
A
F
A
S
S
E
L
S
N
V
D
Site 139
S901
E
K
R
A
F
A
S
S
E
L
S
N
V
D
G
Site 140
S904
A
F
A
S
S
E
L
S
N
V
D
G
G
D
Y
Site 141
Y911
S
N
V
D
G
G
D
Y
T
T
P
S
K
P
W
Site 142
T912
N
V
D
G
G
D
Y
T
T
P
S
K
P
W
D
Site 143
T913
V
D
G
G
D
Y
T
T
P
S
K
P
W
D
V
Site 144
S915
G
G
D
Y
T
T
P
S
K
P
W
D
V
A
Q
Site 145
T939
G
V
Y
G
E
L
K
T
F
N
S
D
G
E
W
Site 146
S942
G
E
L
K
T
F
N
S
D
G
E
W
A
V
V
Site 147
S952
E
W
A
V
V
P
P
S
H
T
K
G
S
L
L
Site 148
S981
V
F
M
T
P
G
N
S
F
A
P
G
H
R
Q
Site 149
S995
Q
L
W
K
P
F
V
S
F
E
Q
N
D
Q
P
Site 150
S1004
E
Q
N
D
Q
P
K
S
G
E
N
G
L
N
K
Site 151
S1014
N
G
L
N
K
G
F
S
F
I
F
H
E
D
L
Site 152
S1038
E
D
P
G
L
E
Y
S
F
S
S
F
D
L
S
Site 153
S1040
P
G
L
E
Y
S
F
S
S
F
D
L
S
N
P
Site 154
S1041
G
L
E
Y
S
F
S
S
F
D
L
S
N
P
F
Site 155
S1045
S
F
S
S
F
D
L
S
N
P
F
S
Q
V
L
Site 156
S1065
F
E
P
E
G
I
A
S
F
S
P
S
F
K
P
Site 157
S1067
P
E
G
I
A
S
F
S
P
S
F
K
P
K
S
Site 158
S1074
S
P
S
F
K
P
K
S
I
L
C
S
D
S
D
Site 159
S1078
K
P
K
S
I
L
C
S
D
S
D
S
E
V
F
Site 160
S1080
K
S
I
L
C
S
D
S
D
S
E
V
F
H
P
Site 161
S1082
I
L
C
S
D
S
D
S
E
V
F
H
P
R
I
Site 162
T1095
R
I
C
G
V
D
R
T
Q
Y
R
A
I
R
I
Site 163
Y1097
C
G
V
D
R
T
Q
Y
R
A
I
R
I
S
P
Site 164
S1103
Q
Y
R
A
I
R
I
S
P
R
T
H
F
R
P
Site 165
T1106
A
I
R
I
S
P
R
T
H
F
R
P
I
S
A
Site 166
S1112
R
T
H
F
R
P
I
S
A
S
E
L
S
P
G
Site 167
S1114
H
F
R
P
I
S
A
S
E
L
S
P
G
G
G
Site 168
S1117
P
I
S
A
S
E
L
S
P
G
G
G
S
E
S
Site 169
S1122
E
L
S
P
G
G
G
S
E
S
E
F
E
S
E
Site 170
S1124
S
P
G
G
G
S
E
S
E
F
E
S
E
K
D
Site 171
S1128
G
S
E
S
E
F
E
S
E
K
D
E
A
N
I
Site 172
S1139
E
A
N
I
P
I
P
S
Q
V
D
I
F
E
D
Site 173
Y1165
A
E
K
E
G
H
Y
Y
G
K
S
E
L
E
S
Site 174
S1168
E
G
H
Y
Y
G
K
S
E
L
E
S
G
K
F
Site 175
S1172
Y
G
K
S
E
L
E
S
G
K
F
L
P
R
L
Site 176
S1182
F
L
P
R
L
K
K
S
G
M
E
K
S
A
Q
Site 177
S1187
K
K
S
G
M
E
K
S
A
Q
T
S
L
D
S
Site 178
S1191
M
E
K
S
A
Q
T
S
L
D
S
Q
E
E
S
Site 179
S1194
S
A
Q
T
S
L
D
S
Q
E
E
S
T
G
I
Site 180
S1198
S
L
D
S
Q
E
E
S
T
G
I
L
S
V
G
Site 181
S1203
E
E
S
T
G
I
L
S
V
G
K
Q
N
Q
C
Site 182
S1218
L
E
C
S
M
N
E
S
L
E
I
D
L
E
S
Site 183
S1225
S
L
E
I
D
L
E
S
S
E
A
N
C
K
I
Site 184
Y1255
A
G
C
Q
F
P
A
Y
E
D
N
P
V
S
S
Site 185
Y1293
T
W
W
E
K
A
L
Y
S
P
L
F
P
A
S
Site 186
S1294
W
W
E
K
A
L
Y
S
P
L
F
P
A
S
E
Site 187
S1300
Y
S
P
L
F
P
A
S
E
C
E
E
C
Y
T
Site 188
Y1306
A
S
E
C
E
E
C
Y
T
N
A
K
G
E
S
Site 189
T1307
S
E
C
E
E
C
Y
T
N
A
K
G
E
S
G
Site 190
Y1318
G
E
S
G
L
E
E
Y
P
D
A
K
E
T
P
Site 191
T1324
E
Y
P
D
A
K
E
T
P
S
N
E
E
R
L
Site 192
S1326
P
D
A
K
E
T
P
S
N
E
E
R
L
L
D
Site 193
S1338
L
L
D
F
N
R
V
S
S
V
Y
E
A
R
C
Site 194
S1339
L
D
F
N
R
V
S
S
V
Y
E
A
R
C
T
Site 195
Y1341
F
N
R
V
S
S
V
Y
E
A
R
C
T
G
E
Site 196
T1346
S
V
Y
E
A
R
C
T
G
E
R
D
S
G
A
Site 197
S1351
R
C
T
G
E
R
D
S
G
A
K
S
D
G
F
Site 198
S1355
E
R
D
S
G
A
K
S
D
G
F
R
G
K
M
Site 199
S1364
G
F
R
G
K
M
C
S
S
A
S
S
T
S
E
Site 200
S1365
F
R
G
K
M
C
S
S
A
S
S
T
S
E
E
Site 201
S1367
G
K
M
C
S
S
A
S
S
T
S
E
E
T
G
Site 202
S1368
K
M
C
S
S
A
S
S
T
S
E
E
T
G
S
Site 203
T1369
M
C
S
S
A
S
S
T
S
E
E
T
G
S
E
Site 204
S1370
C
S
S
A
S
S
T
S
E
E
T
G
S
E
G
Site 205
S1375
S
T
S
E
E
T
G
S
E
G
G
G
E
W
V
Site 206
S1385
G
G
E
W
V
G
P
S
E
E
E
L
F
S
R
Site 207
S1391
P
S
E
E
E
L
F
S
R
T
H
L
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation