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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SORL1
Full Name:
Sortilin-related receptor
Alias:
C11orf32; Gp250; LDLR relative with 11 ligand-binding repeats; Low-density lipoprotein receptor relative with 11 ligand-binding repeats; LR11; LRP9; SORL; SorLA; SorLA-1; Sortilin-related receptor; Sortilin-related receptor, L (DLR class) A repeats-containing; Sorting protein-related receptor containing LDLR class A repeats
Type:
Cell surface; Receptor, misc.
Mass (Da):
248441
Number AA:
2214
UniProt ID:
Q92673
International Prot ID:
IPI00022608
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005887
GO:0016020
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0004871
GO:0004872
GO:0004888
PhosphoSite+
KinaseNET
Biological Process:
GO:0006066
GO:0006629
GO:0006810
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S5
_
_
_
M
A
T
R
S
S
R
R
E
S
R
L
Site 2
S6
_
_
M
A
T
R
S
S
R
R
E
S
R
L
P
Site 3
S10
T
R
S
S
R
R
E
S
R
L
P
F
L
F
T
Site 4
T32
G
A
L
C
E
V
W
T
Q
R
L
H
G
G
S
Site 5
S39
T
Q
R
L
H
G
G
S
A
P
L
P
Q
D
R
Site 6
S70
R
G
D
A
R
G
A
S
R
A
D
E
K
P
L
Site 7
S82
K
P
L
R
R
K
R
S
A
A
L
Q
P
E
P
Site 8
S114
V
H
W
A
G
E
K
S
N
V
I
V
A
L
A
Site 9
Y136
R
P
K
S
S
D
V
Y
V
S
Y
D
Y
G
K
Site 10
Y139
S
S
D
V
Y
V
S
Y
D
Y
G
K
S
F
K
Site 11
S318
K
V
V
H
L
L
G
S
E
Q
Q
S
S
V
Q
Site 12
S322
L
L
G
S
E
Q
Q
S
S
V
Q
L
W
V
S
Site 13
S329
S
S
V
Q
L
W
V
S
F
G
R
K
P
M
R
Site 14
S375
N
R
T
N
L
Y
I
S
E
A
E
G
L
K
F
Site 15
S385
E
G
L
K
F
S
L
S
L
E
N
V
L
Y
Y
Site 16
T598
G
E
K
S
T
V
F
T
I
F
G
S
N
K
E
Site 17
S872
F
R
L
T
I
V
N
S
S
V
L
D
R
P
R
Site 18
S873
R
L
T
I
V
N
S
S
V
L
D
R
P
R
A
Site 19
Y1719
N
L
L
V
N
T
L
Y
T
V
R
V
A
A
V
Site 20
T1811
S
H
K
V
G
N
L
T
A
H
T
S
Y
E
I
Site 21
T1824
E
I
S
A
W
A
K
T
D
L
G
D
S
P
L
Site 22
Y1874
N
V
V
Y
G
I
F
Y
A
T
S
F
L
D
L
Site 23
Y2159
G
V
G
F
A
I
L
Y
T
K
H
R
R
L
Q
Site 24
T2160
V
G
F
A
I
L
Y
T
K
H
R
R
L
Q
S
Site 25
S2167
T
K
H
R
R
L
Q
S
S
F
T
A
F
A
N
Site 26
S2168
K
H
R
R
L
Q
S
S
F
T
A
F
A
N
S
Site 27
T2170
R
R
L
Q
S
S
F
T
A
F
A
N
S
H
Y
Site 28
S2175
S
F
T
A
F
A
N
S
H
Y
S
S
R
L
G
Site 29
Y2177
T
A
F
A
N
S
H
Y
S
S
R
L
G
S
A
Site 30
S2178
A
F
A
N
S
H
Y
S
S
R
L
G
S
A
I
Site 31
S2179
F
A
N
S
H
Y
S
S
R
L
G
S
A
I
F
Site 32
S2183
H
Y
S
S
R
L
G
S
A
I
F
S
S
G
D
Site 33
S2187
R
L
G
S
A
I
F
S
S
G
D
D
L
G
E
Site 34
S2188
L
G
S
A
I
F
S
S
G
D
D
L
G
E
D
Site 35
S2206
A
P
M
I
T
G
F
S
D
D
V
P
M
V
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation