KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
CENPI
Full Name:
Centromere protein I
Alias:
Interphase centromere complex protein 19
Type:
Mass (Da):
86720
Number AA:
756
UniProt ID:
Q92674
International Prot ID:
IPI00552142
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0000775
GO:0005634
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0007548;
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T16
N
V
Q
A
Q
N
R
T
S
Q
G
S
S
S
F
Site 2
S17
V
Q
A
Q
N
R
T
S
Q
G
S
S
S
F
Q
Site 3
S20
Q
N
R
T
S
Q
G
S
S
S
F
Q
T
T
L
Site 4
S21
N
R
T
S
Q
G
S
S
S
F
Q
T
T
L
S
Site 5
S22
R
T
S
Q
G
S
S
S
F
Q
T
T
L
S
A
Site 6
T25
Q
G
S
S
S
F
Q
T
T
L
S
A
W
K
V
Site 7
T26
G
S
S
S
F
Q
T
T
L
S
A
W
K
V
K
Site 8
S28
S
S
F
Q
T
T
L
S
A
W
K
V
K
Q
D
Site 9
S37
W
K
V
K
Q
D
P
S
N
S
K
N
I
S
K
Site 10
S39
V
K
Q
D
P
S
N
S
K
N
I
S
K
H
G
Site 11
S43
P
S
N
S
K
N
I
S
K
H
G
Q
N
N
P
Site 12
Y54
Q
N
N
P
V
G
D
Y
E
H
A
D
D
Q
A
Site 13
S81
E
K
G
P
I
K
A
S
Q
N
K
D
K
T
L
Site 14
T87
A
S
Q
N
K
D
K
T
L
E
K
H
L
K
T
Site 15
T94
T
L
E
K
H
L
K
T
V
E
N
V
A
W
K
Site 16
Y206
P
Y
V
C
H
L
L
Y
L
L
T
K
K
E
N
Site 17
Y261
L
P
V
R
K
K
I
Y
F
K
N
S
E
N
L
Site 18
S284
K
Q
R
N
R
G
P
S
P
E
P
L
K
L
M
Site 19
S308
K
R
K
W
N
S
L
S
V
I
P
V
L
N
S
Site 20
S315
S
V
I
P
V
L
N
S
S
S
Y
T
K
E
C
Site 21
S317
I
P
V
L
N
S
S
S
Y
T
K
E
C
G
K
Site 22
Y318
P
V
L
N
S
S
S
Y
T
K
E
C
G
K
K
Site 23
S328
E
C
G
K
K
E
M
S
L
S
D
C
L
N
R
Site 24
S330
G
K
K
E
M
S
L
S
D
C
L
N
R
S
G
Site 25
S336
L
S
D
C
L
N
R
S
G
S
F
P
L
E
Q
Site 26
S338
D
C
L
N
R
S
G
S
F
P
L
E
Q
L
Q
Site 27
S346
F
P
L
E
Q
L
Q
S
F
P
Q
L
L
Q
N
Site 28
S365
E
L
P
S
Q
M
G
S
V
L
N
N
S
L
L
Site 29
Y440
Y
S
C
E
A
F
L
Y
K
S
L
P
L
W
D
Site 30
S492
S
T
I
Y
F
K
C
S
V
L
Q
S
L
K
E
Site 31
S496
F
K
C
S
V
L
Q
S
L
K
E
L
L
Q
N
Site 32
T518
D
I
H
M
K
P
V
T
N
S
P
L
E
T
T
Site 33
S520
H
M
K
P
V
T
N
S
P
L
E
T
T
L
G
Site 34
T524
V
T
N
S
P
L
E
T
T
L
G
G
S
M
N
Site 35
T525
T
N
S
P
L
E
T
T
L
G
G
S
M
N
S
Site 36
S532
T
L
G
G
S
M
N
S
V
S
K
L
I
H
Y
Site 37
S552
T
T
A
M
R
L
E
S
N
N
T
F
L
L
H
Site 38
Y572
Y
E
K
V
C
D
I
Y
I
N
Y
N
L
P
L
Site 39
T626
K
N
E
L
V
Q
K
T
K
S
E
F
N
F
S
Site 40
S628
E
L
V
Q
K
T
K
S
E
F
N
F
S
S
K
Site 41
S633
T
K
S
E
F
N
F
S
S
K
T
Y
Q
E
F
Site 42
Y637
F
N
F
S
S
K
T
Y
Q
E
F
N
H
Y
L
Site 43
Y643
T
Y
Q
E
F
N
H
Y
L
T
S
M
V
G
C
Site 44
T653
S
M
V
G
C
L
W
T
S
K
P
F
G
K
G
Site 45
Y662
K
P
F
G
K
G
I
Y
I
D
P
E
I
L
E
Site 46
S679
G
V
A
E
Y
K
N
S
L
N
V
V
H
H
P
Site 47
S700
V
S
F
L
L
Q
E
S
P
E
E
R
T
V
N
Site 48
T705
Q
E
S
P
E
E
R
T
V
N
V
S
S
I
R
Site 49
S709
E
E
R
T
V
N
V
S
S
I
R
G
K
K
W
Site 50
S710
E
R
T
V
N
V
S
S
I
R
G
K
K
W
S
Site 51
Y719
R
G
K
K
W
S
W
Y
L
D
Y
L
F
S
Q
Site 52
Y722
K
W
S
W
Y
L
D
Y
L
F
S
Q
G
L
Q
Site 53
S725
W
Y
L
D
Y
L
F
S
Q
G
L
Q
G
L
K
Site 54
S742
I
R
S
S
V
H
H
S
S
I
P
R
A
E
G
Site 55
S743
R
S
S
V
H
H
S
S
I
P
R
A
E
G
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation