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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PVRL2
Full Name:
Poliovirus receptor-related protein 2
Alias:
CD112; CD112 antigen; Herpes virus entry mediator B; Herpesvirus entry mediator B; HveB; HVEB; Nectin-2; Poliovirus receptor related protein 2; Poliovirus receptor-related 2; PRR2; PVR2; PVRR2
Type:
Adhesion protein
Mass (Da):
57742
Number AA:
538
UniProt ID:
Q92692
International Prot ID:
IPI00022661
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0009986
GO:0016021
GO:0005915
Uniprot
OncoNet
Molecular Function:
GO:0050839
GO:0015026
GO:0042803
PhosphoSite+
KinaseNET
Biological Process:
GO:0051856
GO:0007156
GO:0002891
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S10
R
A
A
A
L
L
P
S
R
S
P
P
T
P
L
Site 2
T172
Q
A
E
A
Q
K
V
T
F
S
Q
D
P
T
T
Site 3
S185
T
T
V
A
L
C
I
S
K
E
G
R
P
P
A
Site 4
S228
S
R
F
T
L
V
P
S
G
R
A
D
G
V
T
Site 5
T390
R
Q
Q
R
K
E
Q
T
L
Q
G
A
E
E
D
Site 6
S405
E
D
L
E
G
P
P
S
Y
K
P
P
T
P
K
Site 7
Y406
D
L
E
G
P
P
S
Y
K
P
P
T
P
K
A
Site 8
T410
P
P
S
Y
K
P
P
T
P
K
A
K
L
E
A
Site 9
T426
E
M
P
S
Q
L
F
T
L
G
A
S
E
H
S
Site 10
S433
T
L
G
A
S
E
H
S
P
L
K
T
P
Y
F
Site 11
T437
S
E
H
S
P
L
K
T
P
Y
F
D
A
G
A
Site 12
Y439
H
S
P
L
K
T
P
Y
F
D
A
G
A
S
C
Site 13
S445
P
Y
F
D
A
G
A
S
C
T
E
Q
E
M
P
Site 14
Y454
T
E
Q
E
M
P
R
Y
H
E
L
P
T
L
E
Site 15
T459
P
R
Y
H
E
L
P
T
L
E
E
R
S
G
P
Site 16
T472
G
P
L
H
P
G
A
T
S
L
G
S
P
I
P
Site 17
S491
P
P
A
V
E
D
V
S
L
D
L
E
D
E
E
Site 18
Y505
E
G
E
E
E
E
E
Y
L
D
K
I
N
P
I
Site 19
Y513
L
D
K
I
N
P
I
Y
D
A
L
S
Y
S
S
Site 20
S517
N
P
I
Y
D
A
L
S
Y
S
S
P
S
D
S
Site 21
Y518
P
I
Y
D
A
L
S
Y
S
S
P
S
D
S
Y
Site 22
S519
I
Y
D
A
L
S
Y
S
S
P
S
D
S
Y
Q
Site 23
S520
Y
D
A
L
S
Y
S
S
P
S
D
S
Y
Q
G
Site 24
S522
A
L
S
Y
S
S
P
S
D
S
Y
Q
G
K
G
Site 25
S524
S
Y
S
S
P
S
D
S
Y
Q
G
K
G
F
V
Site 26
Y525
Y
S
S
P
S
D
S
Y
Q
G
K
G
F
V
M
Site 27
Y537
F
V
M
S
R
A
M
Y
V
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation