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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PRCC
Full Name:
Proline-rich protein PRCC
Alias:
Papillary renal cell carcinoma (translocation-associated); Papillary renal cell carcinoma translocation associated gene protein; Papillary renal cell carcinoma translocation-associated gene protein; Pr; RCCP1
Type:
Unknown function
Mass (Da):
52418
Number AA:
491
UniProt ID:
Q92733
International Prot ID:
IPI00294618
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y6
_
_
M
S
L
V
A
Y
A
S
S
D
E
S
E
Site 2
S8
M
S
L
V
A
Y
A
S
S
D
E
S
E
P
D
Site 3
S9
S
L
V
A
Y
A
S
S
D
E
S
E
P
D
E
Site 4
S12
A
Y
A
S
S
D
E
S
E
P
D
E
A
E
P
Site 5
T72
P
L
L
L
P
P
P
T
G
D
P
R
L
Q
P
Site 6
S97
F
P
P
P
P
G
V
S
P
A
E
A
A
G
V
Site 7
S114
G
L
G
L
G
L
P
S
P
R
G
P
G
L
N
Site 8
S157
P
E
L
H
K
G
D
S
D
S
E
E
D
E
P
Site 9
S159
L
H
K
G
D
S
D
S
E
E
D
E
P
T
K
Site 10
T165
D
S
E
E
D
E
P
T
K
K
K
T
I
L
Q
Site 11
T169
D
E
P
T
K
K
K
T
I
L
Q
G
S
S
E
Site 12
S174
K
K
T
I
L
Q
G
S
S
E
G
T
G
L
S
Site 13
S175
K
T
I
L
Q
G
S
S
E
G
T
G
L
S
A
Site 14
S181
S
S
E
G
T
G
L
S
A
L
L
P
Q
P
K
Site 15
T191
L
P
Q
P
K
N
L
T
V
K
E
T
N
R
L
Site 16
T195
K
N
L
T
V
K
E
T
N
R
L
L
L
P
H
Site 17
S205
L
L
L
P
H
A
F
S
R
K
P
S
D
G
S
Site 18
S209
H
A
F
S
R
K
P
S
D
G
S
P
D
T
K
Site 19
S212
S
R
K
P
S
D
G
S
P
D
T
K
P
S
R
Site 20
T215
P
S
D
G
S
P
D
T
K
P
S
R
L
A
S
Site 21
S218
G
S
P
D
T
K
P
S
R
L
A
S
K
T
K
Site 22
S222
T
K
P
S
R
L
A
S
K
T
K
T
S
S
L
Site 23
T224
P
S
R
L
A
S
K
T
K
T
S
S
L
A
P
Site 24
T226
R
L
A
S
K
T
K
T
S
S
L
A
P
V
V
Site 25
S228
A
S
K
T
K
T
S
S
L
A
P
V
V
G
T
Site 26
T237
A
P
V
V
G
T
T
T
T
T
P
S
P
S
A
Site 27
T238
P
V
V
G
T
T
T
T
T
P
S
P
S
A
I
Site 28
T239
V
V
G
T
T
T
T
T
P
S
P
S
A
I
K
Site 29
S241
G
T
T
T
T
T
P
S
P
S
A
I
K
A
A
Site 30
S243
T
T
T
T
P
S
P
S
A
I
K
A
A
A
K
Site 31
T261
L
Q
V
T
K
Q
I
T
Q
E
E
D
D
S
D
Site 32
S267
I
T
Q
E
E
D
D
S
D
E
E
V
A
P
E
Site 33
S278
V
A
P
E
N
F
F
S
L
P
E
K
A
E
P
Site 34
Y291
E
P
P
G
V
E
P
Y
P
Y
P
I
P
T
V
Site 35
Y293
P
G
V
E
P
Y
P
Y
P
I
P
T
V
P
E
Site 36
T297
P
Y
P
Y
P
I
P
T
V
P
E
E
L
P
P
Site 37
Y342
M
P
K
P
G
D
D
Y
S
Y
N
Q
F
S
T
Site 38
S343
P
K
P
G
D
D
Y
S
Y
N
Q
F
S
T
Y
Site 39
Y344
K
P
G
D
D
Y
S
Y
N
Q
F
S
T
Y
G
Site 40
Y360
A
N
A
A
G
A
Y
Y
Q
D
Y
Y
S
G
G
Site 41
Y363
A
G
A
Y
Y
Q
D
Y
Y
S
G
G
Y
Y
P
Site 42
Y364
G
A
Y
Y
Q
D
Y
Y
S
G
G
Y
Y
P
A
Site 43
Y369
D
Y
Y
S
G
G
Y
Y
P
A
Q
D
P
A
L
Site 44
S387
Q
E
I
A
P
D
A
S
F
I
D
D
E
A
F
Site 45
S429
A
Q
Q
W
M
T
K
S
L
T
E
E
K
T
M
Site 46
T431
Q
W
M
T
K
S
L
T
E
E
K
T
M
K
S
Site 47
T435
K
S
L
T
E
E
K
T
M
K
S
F
S
K
K
Site 48
S438
T
E
E
K
T
M
K
S
F
S
K
K
K
G
E
Site 49
S440
E
K
T
M
K
S
F
S
K
K
K
G
E
Q
P
Site 50
T458
Q
R
R
K
H
Q
I
T
Y
L
I
H
Q
A
K
Site 51
Y459
R
R
K
H
Q
I
T
Y
L
I
H
Q
A
K
E
Site 52
T474
R
E
L
E
L
K
N
T
W
S
E
N
K
L
S
Site 53
S476
L
E
L
K
N
T
W
S
E
N
K
L
S
R
R
Site 54
S481
T
W
S
E
N
K
L
S
R
R
Q
T
Q
A
K
Site 55
T485
N
K
L
S
R
R
Q
T
Q
A
K
Y
G
F
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation