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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TFG
Full Name:
Protein TFG
Alias:
FLJ36137; TF6; TRK-fused gene; TRK-fused gene (NOTE: non-standard symbol and name); TRK-fused gene protein; TRKT3; TRKT3 oncogene
Type:
Adaptor/scaffold
Mass (Da):
43448
Number AA:
400
UniProt ID:
Q92734
International Prot ID:
IPI00294619
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0044424
GO:0044464
Uniprot
OncoNet
Molecular Function:
GO:0004871
GO:0005488
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0009966
GO:0009967
GO:0010627
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
N
G
Q
L
D
L
S
G
K
L
I
I
K
A
Site 2
T32
P
I
H
N
E
D
I
T
Y
D
E
L
V
L
M
Site 3
Y33
I
H
N
E
D
I
T
Y
D
E
L
V
L
M
M
Site 4
S50
V
F
R
G
K
L
L
S
N
D
E
V
T
I
K
Site 5
Y58
N
D
E
V
T
I
K
Y
K
D
E
D
G
D
L
Site 6
T67
D
E
D
G
D
L
I
T
I
F
D
S
S
D
L
Site 7
S99
G
Q
P
R
P
L
E
S
S
Q
V
K
Y
L
R
Site 8
S100
Q
P
R
P
L
E
S
S
Q
V
K
Y
L
R
R
Site 9
Y104
L
E
S
S
Q
V
K
Y
L
R
R
E
L
I
E
Site 10
S122
K
V
N
R
L
L
D
S
L
E
P
P
G
E
P
Site 11
S132
P
P
G
E
P
G
P
S
T
N
I
P
E
N
D
Site 12
T133
P
G
E
P
G
P
S
T
N
I
P
E
N
D
T
Site 13
T140
T
N
I
P
E
N
D
T
V
D
G
R
E
E
K
Site 14
S148
V
D
G
R
E
E
K
S
A
S
D
S
S
G
K
Site 15
S150
G
R
E
E
K
S
A
S
D
S
S
G
K
Q
S
Site 16
S152
E
E
K
S
A
S
D
S
S
G
K
Q
S
T
Q
Site 17
S153
E
K
S
A
S
D
S
S
G
K
Q
S
T
Q
V
Site 18
S157
S
D
S
S
G
K
Q
S
T
Q
V
M
A
A
S
Site 19
S183
E
I
N
K
N
V
M
S
A
F
G
L
T
D
D
Site 20
S193
G
L
T
D
D
Q
V
S
G
P
P
S
A
P
A
Site 21
S197
D
Q
V
S
G
P
P
S
A
P
A
E
D
R
S
Site 22
S204
S
A
P
A
E
D
R
S
G
T
P
D
S
I
A
Site 23
T206
P
A
E
D
R
S
G
T
P
D
S
I
A
S
S
Site 24
S209
D
R
S
G
T
P
D
S
I
A
S
S
S
S
A
Site 25
S212
G
T
P
D
S
I
A
S
S
S
S
A
A
H
P
Site 26
S213
T
P
D
S
I
A
S
S
S
S
A
A
H
P
P
Site 27
S214
P
D
S
I
A
S
S
S
S
A
A
H
P
P
G
Site 28
S215
D
S
I
A
S
S
S
S
A
A
H
P
P
G
V
Site 29
Y229
V
Q
P
Q
Q
P
P
Y
T
G
A
Q
T
Q
A
Site 30
Y244
G
Q
I
E
G
Q
M
Y
Q
Q
Y
Q
Q
Q
A
Site 31
Y247
E
G
Q
M
Y
Q
Q
Y
Q
Q
Q
A
G
Y
G
Site 32
Y272
P
Q
Q
Y
G
I
Q
Y
S
A
S
Y
S
Q
Q
Site 33
S273
Q
Q
Y
G
I
Q
Y
S
A
S
Y
S
Q
Q
T
Site 34
S275
Y
G
I
Q
Y
S
A
S
Y
S
Q
Q
T
G
P
Site 35
S277
I
Q
Y
S
A
S
Y
S
Q
Q
T
G
P
Q
Q
Site 36
S297
G
Y
G
Q
Q
P
T
S
Q
A
P
A
P
A
F
Site 37
S305
Q
A
P
A
P
A
F
S
G
Q
P
Q
Q
L
P
Site 38
Y324
Q
Q
Y
Q
A
S
N
Y
P
A
Q
T
Y
T
A
Site 39
Y329
S
N
Y
P
A
Q
T
Y
T
A
Q
T
S
Q
P
Site 40
S334
Q
T
Y
T
A
Q
T
S
Q
P
T
N
Y
T
V
Site 41
T340
T
S
Q
P
T
N
Y
T
V
A
P
A
S
Q
P
Site 42
S345
N
Y
T
V
A
P
A
S
Q
P
G
M
A
P
S
Site 43
S352
S
Q
P
G
M
A
P
S
Q
P
G
A
Y
Q
P
Site 44
Y357
A
P
S
Q
P
G
A
Y
Q
P
R
P
G
F
T
Site 45
S365
Q
P
R
P
G
F
T
S
L
P
G
S
T
M
T
Site 46
S369
G
F
T
S
L
P
G
S
T
M
T
P
P
P
S
Site 47
T370
F
T
S
L
P
G
S
T
M
T
P
P
P
S
G
Site 48
T372
S
L
P
G
S
T
M
T
P
P
P
S
G
P
N
Site 49
S376
S
T
M
T
P
P
P
S
G
P
N
P
Y
A
R
Site 50
Y381
P
P
S
G
P
N
P
Y
A
R
N
R
P
P
F
Site 51
Y392
R
P
P
F
G
Q
G
Y
T
Q
P
G
P
G
Y
Site 52
T393
P
P
F
G
Q
G
Y
T
Q
P
G
P
G
Y
R
Site 53
Y399
Y
T
Q
P
G
P
G
Y
R
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation