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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SYN2
Full Name:
Synapsin-2
Alias:
synapsin II; SYNII; SYNIIa; SYNIIb
Type:
Vesicle protein
Mass (Da):
62847
Number AA:
582
UniProt ID:
Q92777
International Prot ID:
IPI00023302
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030054
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0003824
PhosphoSite+
KinaseNET
Biological Process:
GO:0007269
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S10
N
F
L
R
R
R
L
S
D
S
S
F
I
A
N
Site 2
S12
L
R
R
R
L
S
D
S
S
F
I
A
N
L
P
Site 3
S13
R
R
R
L
S
D
S
S
F
I
A
N
L
P
N
Site 4
T36
P
E
P
Q
Q
A
P
T
P
P
P
P
G
P
G
Site 5
S46
P
P
G
P
G
A
A
S
A
S
A
A
P
P
T
Site 6
S48
G
P
G
A
A
S
A
S
A
A
P
P
T
A
S
Site 7
T53
S
A
S
A
A
P
P
T
A
S
P
G
P
E
R
Site 8
S55
S
A
A
P
P
T
A
S
P
G
P
E
R
T
P
Site 9
T61
A
S
P
G
P
E
R
T
P
P
A
A
S
A
P
Site 10
S66
E
R
T
P
P
A
A
S
A
P
A
P
P
P
A
Site 11
T75
P
A
P
P
P
A
R
T
P
S
V
G
S
S
L
Site 12
S77
P
P
P
A
R
T
P
S
V
G
S
S
L
F
S
Site 13
S80
A
R
T
P
S
V
G
S
S
L
F
S
S
L
S
Site 14
S81
R
T
P
S
V
G
S
S
L
F
S
S
L
S
Q
Site 15
S87
S
S
L
F
S
S
L
S
Q
A
V
K
Q
T
A
Site 16
Y139
G
K
K
V
L
G
D
Y
D
I
K
V
E
Q
A
Site 17
T172
M
Q
V
L
R
N
G
T
K
V
V
R
S
F
R
Site 18
S177
N
G
T
K
V
V
R
S
F
R
P
D
F
V
L
Site 19
S218
P
S
I
N
S
L
E
S
I
Y
N
F
C
D
K
Site 20
T250
K
F
P
L
I
E
Q
T
Y
Y
P
N
H
K
E
Site 21
Y251
F
P
L
I
E
Q
T
Y
Y
P
N
H
K
E
M
Site 22
Y252
P
L
I
E
Q
T
Y
Y
P
N
H
K
E
M
L
Site 23
T260
P
N
H
K
E
M
L
T
L
P
T
F
P
V
V
Site 24
S275
V
K
I
G
H
A
H
S
G
M
G
K
V
K
V
Site 25
Y312
E
P
F
I
D
S
K
Y
D
I
R
V
Q
K
I
Site 26
Y326
I
G
N
N
Y
K
A
Y
M
R
T
S
I
S
G
Site 27
T337
S
I
S
G
N
W
K
T
N
T
G
S
A
M
L
Site 28
T339
S
G
N
W
K
T
N
T
G
S
A
M
L
E
Q
Site 29
S341
N
W
K
T
N
T
G
S
A
M
L
E
Q
I
A
Site 30
Y353
Q
I
A
M
S
D
R
Y
K
L
W
V
D
T
C
Site 31
Y383
H
G
K
D
G
K
D
Y
I
F
E
V
M
D
C
Site 32
S419
S
K
M
N
Q
L
L
S
R
T
P
A
L
S
P
Site 33
T421
M
N
Q
L
L
S
R
T
P
A
L
S
P
Q
R
Site 34
S425
L
S
R
T
P
A
L
S
P
Q
R
P
L
T
T
Site 35
T431
L
S
P
Q
R
P
L
T
T
Q
Q
P
Q
S
G
Site 36
T432
S
P
Q
R
P
L
T
T
Q
Q
P
Q
S
G
T
Site 37
S437
L
T
T
Q
Q
P
Q
S
G
T
L
K
D
P
D
Site 38
S445
G
T
L
K
D
P
D
S
S
K
T
P
P
Q
R
Site 39
S446
T
L
K
D
P
D
S
S
K
T
P
P
Q
R
P
Site 40
T448
K
D
P
D
S
S
K
T
P
P
Q
R
P
P
P
Site 41
S482
R
R
L
P
P
G
P
S
L
P
P
S
S
S
S
Site 42
S486
P
G
P
S
L
P
P
S
S
S
S
S
S
S
S
Site 43
S487
G
P
S
L
P
P
S
S
S
S
S
S
S
S
S
Site 44
S488
P
S
L
P
P
S
S
S
S
S
S
S
S
S
S
Site 45
S489
S
L
P
P
S
S
S
S
S
S
S
S
S
S
S
Site 46
S490
L
P
P
S
S
S
S
S
S
S
S
S
S
S
A
Site 47
S491
P
P
S
S
S
S
S
S
S
S
S
S
S
A
P
Site 48
S492
P
S
S
S
S
S
S
S
S
S
S
S
A
P
Q
Site 49
S493
S
S
S
S
S
S
S
S
S
S
S
A
P
Q
R
Site 50
S494
S
S
S
S
S
S
S
S
S
S
A
P
Q
R
P
Site 51
S495
S
S
S
S
S
S
S
S
S
A
P
Q
R
P
G
Site 52
S496
S
S
S
S
S
S
S
S
A
P
Q
R
P
G
G
Site 53
T505
P
Q
R
P
G
G
P
T
T
H
G
D
A
P
S
Site 54
T506
Q
R
P
G
G
P
T
T
H
G
D
A
P
S
S
Site 55
S512
T
T
H
G
D
A
P
S
S
S
S
S
L
A
E
Site 56
S513
T
H
G
D
A
P
S
S
S
S
S
L
A
E
A
Site 57
S514
H
G
D
A
P
S
S
S
S
S
L
A
E
A
Q
Site 58
S516
D
A
P
S
S
S
S
S
L
A
E
A
Q
P
P
Site 59
S540
P
H
P
Q
L
N
K
S
Q
S
L
T
N
A
F
Site 60
S542
P
Q
L
N
K
S
Q
S
L
T
N
A
F
S
F
Site 61
T544
L
N
K
S
Q
S
L
T
N
A
F
S
F
S
E
Site 62
S548
Q
S
L
T
N
A
F
S
F
S
E
S
S
F
F
Site 63
S550
L
T
N
A
F
S
F
S
E
S
S
F
F
R
S
Site 64
S552
N
A
F
S
F
S
E
S
S
F
F
R
S
S
A
Site 65
S553
A
F
S
F
S
E
S
S
F
F
R
S
S
A
N
Site 66
S557
S
E
S
S
F
F
R
S
S
A
N
E
D
E
A
Site 67
S558
E
S
S
F
F
R
S
S
A
N
E
D
E
A
K
Site 68
S571
A
K
A
E
T
I
R
S
L
R
K
S
F
A
S
Site 69
S575
T
I
R
S
L
R
K
S
F
A
S
L
F
S
D
Site 70
S578
S
L
R
K
S
F
A
S
L
F
S
D
_
_
_
Site 71
S581
K
S
F
A
S
L
F
S
D
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation