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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TAF15
Full Name:
TATA-binding protein-associated factor 2N
Alias:
hTAFII68; Npl3; RBP56; RNA-binding protein 56; TAF(II)68; TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor; TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa; TAF2N; TAFII68; TATA-binding protein associated factor 2N
Type:
Translation; RNA binding protein
Mass (Da):
61830
Number AA:
592
UniProt ID:
Q92804
International Prot ID:
IPI00294426
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0003723
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
S
D
S
G
S
Y
G
Q
S
G
G
E
Site 2
S10
D
S
G
S
Y
G
Q
S
G
G
E
Q
Q
S
Y
Site 3
S16
Q
S
G
G
E
Q
Q
S
Y
S
T
Y
G
N
P
Site 4
Y17
S
G
G
E
Q
Q
S
Y
S
T
Y
G
N
P
G
Site 5
S18
G
G
E
Q
Q
S
Y
S
T
Y
G
N
P
G
S
Site 6
Y20
E
Q
Q
S
Y
S
T
Y
G
N
P
G
S
Q
G
Site 7
S25
S
T
Y
G
N
P
G
S
Q
G
Y
G
Q
A
S
Site 8
Y28
G
N
P
G
S
Q
G
Y
G
Q
A
S
Q
S
Y
Site 9
S32
S
Q
G
Y
G
Q
A
S
Q
S
Y
S
G
Y
G
Site 10
S34
G
Y
G
Q
A
S
Q
S
Y
S
G
Y
G
Q
T
Site 11
S36
G
Q
A
S
Q
S
Y
S
G
Y
G
Q
T
T
D
Site 12
Y38
A
S
Q
S
Y
S
G
Y
G
Q
T
T
D
S
S
Site 13
T41
S
Y
S
G
Y
G
Q
T
T
D
S
S
Y
G
Q
Site 14
S44
G
Y
G
Q
T
T
D
S
S
Y
G
Q
N
Y
S
Site 15
S45
Y
G
Q
T
T
D
S
S
Y
G
Q
N
Y
S
G
Site 16
Y46
G
Q
T
T
D
S
S
Y
G
Q
N
Y
S
G
Y
Site 17
Y50
D
S
S
Y
G
Q
N
Y
S
G
Y
S
S
Y
G
Site 18
S51
S
S
Y
G
Q
N
Y
S
G
Y
S
S
Y
G
Q
Site 19
Y53
Y
G
Q
N
Y
S
G
Y
S
S
Y
G
Q
S
Q
Site 20
S55
Q
N
Y
S
G
Y
S
S
Y
G
Q
S
Q
S
G
Site 21
Y56
N
Y
S
G
Y
S
S
Y
G
Q
S
Q
S
G
Y
Site 22
S59
G
Y
S
S
Y
G
Q
S
Q
S
G
Y
S
Q
S
Site 23
S61
S
S
Y
G
Q
S
Q
S
G
Y
S
Q
S
Y
G
Site 24
Y63
Y
G
Q
S
Q
S
G
Y
S
Q
S
Y
G
G
Y
Site 25
S64
G
Q
S
Q
S
G
Y
S
Q
S
Y
G
G
Y
E
Site 26
S66
S
Q
S
G
Y
S
Q
S
Y
G
G
Y
E
N
Q
Site 27
Y70
Y
S
Q
S
Y
G
G
Y
E
N
Q
K
Q
S
S
Site 28
S77
Y
E
N
Q
K
Q
S
S
Y
S
Q
Q
P
Y
N
Site 29
Y78
E
N
Q
K
Q
S
S
Y
S
Q
Q
P
Y
N
N
Site 30
S79
N
Q
K
Q
S
S
Y
S
Q
Q
P
Y
N
N
Q
Site 31
Y83
S
S
Y
S
Q
Q
P
Y
N
N
Q
G
Q
Q
Q
Site 32
S94
G
Q
Q
Q
N
M
E
S
S
G
S
Q
G
G
R
Site 33
S95
Q
Q
Q
N
M
E
S
S
G
S
Q
G
G
R
A
Site 34
S97
Q
N
M
E
S
S
G
S
Q
G
G
R
A
P
S
Site 35
S104
S
Q
G
G
R
A
P
S
Y
D
Q
P
D
Y
G
Site 36
Y105
Q
G
G
R
A
P
S
Y
D
Q
P
D
Y
G
Q
Site 37
Y110
P
S
Y
D
Q
P
D
Y
G
Q
Q
D
S
Y
D
Site 38
S115
P
D
Y
G
Q
Q
D
S
Y
D
Q
Q
S
G
Y
Site 39
Y116
D
Y
G
Q
Q
D
S
Y
D
Q
Q
S
G
Y
D
Site 40
Y122
S
Y
D
Q
Q
S
G
Y
D
Q
H
Q
G
S
Y
Site 41
S128
G
Y
D
Q
H
Q
G
S
Y
D
E
Q
S
N
Y
Site 42
Y129
Y
D
Q
H
Q
G
S
Y
D
E
Q
S
N
Y
D
Site 43
Y135
S
Y
D
E
Q
S
N
Y
D
Q
Q
H
D
S
Y
Site 44
Y142
Y
D
Q
Q
H
D
S
Y
S
Q
N
Q
Q
S
Y
Site 45
S148
S
Y
S
Q
N
Q
Q
S
Y
H
S
Q
R
E
N
Site 46
Y149
Y
S
Q
N
Q
Q
S
Y
H
S
Q
R
E
N
Y
Site 47
S151
Q
N
Q
Q
S
Y
H
S
Q
R
E
N
Y
S
H
Site 48
Y156
Y
H
S
Q
R
E
N
Y
S
H
H
T
Q
D
D
Site 49
S157
H
S
Q
R
E
N
Y
S
H
H
T
Q
D
D
R
Site 50
T160
R
E
N
Y
S
H
H
T
Q
D
D
R
R
D
V
Site 51
S168
Q
D
D
R
R
D
V
S
R
Y
G
E
D
N
R
Site 52
Y170
D
R
R
D
V
S
R
Y
G
E
D
N
R
G
Y
Site 53
Y177
Y
G
E
D
N
R
G
Y
G
G
S
Q
G
G
G
Site 54
S180
D
N
R
G
Y
G
G
S
Q
G
G
G
R
G
R
Site 55
Y190
G
G
R
G
R
G
G
Y
D
K
D
G
R
G
P
Site 56
T199
K
D
G
R
G
P
M
T
G
S
S
G
G
D
R
Site 57
S201
G
R
G
P
M
T
G
S
S
G
G
D
R
G
G
Site 58
S202
R
G
P
M
T
G
S
S
G
G
D
R
G
G
F
Site 59
Y218
N
F
G
G
H
R
D
Y
G
P
R
T
D
A
D
Site 60
T222
H
R
D
Y
G
P
R
T
D
A
D
S
E
S
D
Site 61
S226
G
P
R
T
D
A
D
S
E
S
D
N
S
D
N
Site 62
S228
R
T
D
A
D
S
E
S
D
N
S
D
N
N
T
Site 63
S231
A
D
S
E
S
D
N
S
D
N
N
T
I
F
V
Site 64
T235
S
D
N
S
D
N
N
T
I
F
V
Q
G
L
G
Site 65
S246
Q
G
L
G
E
G
V
S
T
D
Q
V
G
E
F
Site 66
T247
G
L
G
E
G
V
S
T
D
Q
V
G
E
F
F
Site 67
T262
K
Q
I
G
I
I
K
T
N
K
K
T
G
K
P
Site 68
T266
I
I
K
T
N
K
K
T
G
K
P
M
I
N
L
Site 69
Y274
G
K
P
M
I
N
L
Y
T
D
K
D
T
G
K
Site 70
T279
N
L
Y
T
D
K
D
T
G
K
P
K
G
E
A
Site 71
T287
G
K
P
K
G
E
A
T
V
S
F
D
D
P
P
Site 72
S289
P
K
G
E
A
T
V
S
F
D
D
P
P
S
A
Site 73
S295
V
S
F
D
D
P
P
S
A
K
A
A
I
D
W
Site 74
S316
H
G
N
I
I
K
V
S
F
A
T
R
R
P
E
Site 75
T319
I
I
K
V
S
F
A
T
R
R
P
E
F
M
R
Site 76
S330
E
F
M
R
G
G
G
S
G
G
G
R
R
G
R
Site 77
Y340
G
R
R
G
R
G
G
Y
R
G
R
G
G
F
Q
Site 78
S355
G
R
G
G
D
P
K
S
G
D
W
V
C
P
N
Site 79
S375
M
N
F
A
R
R
N
S
C
N
Q
C
N
E
P
Site 80
S387
N
E
P
R
P
E
D
S
R
P
S
G
G
D
F
Site 81
S390
R
P
E
D
S
R
P
S
G
G
D
F
R
G
R
Site 82
Y399
G
D
F
R
G
R
G
Y
G
G
E
R
G
Y
R
Site 83
Y405
G
Y
G
G
E
R
G
Y
R
G
R
G
G
R
G
Site 84
Y418
R
G
G
D
R
G
G
Y
G
G
D
R
S
G
G
Site 85
S423
G
G
Y
G
G
D
R
S
G
G
G
Y
G
G
D
Site 86
Y427
G
D
R
S
G
G
G
Y
G
G
D
R
S
S
G
Site 87
S432
G
G
Y
G
G
D
R
S
S
G
G
G
Y
S
G
Site 88
S433
G
Y
G
G
D
R
S
S
G
G
G
Y
S
G
D
Site 89
Y437
D
R
S
S
G
G
G
Y
S
G
D
R
S
G
G
Site 90
S438
R
S
S
G
G
G
Y
S
G
D
R
S
G
G
G
Site 91
S442
G
G
Y
S
G
D
R
S
G
G
G
Y
G
G
D
Site 92
Y446
G
D
R
S
G
G
G
Y
G
G
D
R
S
G
G
Site 93
Y455
G
D
R
S
G
G
G
Y
G
G
D
R
G
G
G
Site 94
Y463
G
G
D
R
G
G
G
Y
G
G
D
R
G
G
G
Site 95
Y479
G
G
D
R
G
G
G
Y
G
G
D
R
G
G
Y
Site 96
Y486
Y
G
G
D
R
G
G
Y
G
G
D
R
G
G
G
Site 97
Y501
Y
G
G
D
R
G
G
Y
G
G
D
R
G
G
Y
Site 98
Y522
Y
G
G
D
R
G
G
Y
G
G
D
R
S
R
G
Site 99
S527
G
G
Y
G
G
D
R
S
R
G
G
Y
G
G
D
Site 100
Y531
G
D
R
S
R
G
G
Y
G
G
D
R
G
G
G
Site 101
S539
G
G
D
R
G
G
G
S
G
Y
G
G
D
R
S
Site 102
Y541
D
R
G
G
G
S
G
Y
G
G
D
R
S
G
G
Site 103
S546
S
G
Y
G
G
D
R
S
G
G
Y
G
G
D
R
Site 104
Y549
G
G
D
R
S
G
G
Y
G
G
D
R
S
G
G
Site 105
Y573
Y
G
G
D
R
G
G
Y
G
G
K
M
G
G
R
Site 106
Y583
K
M
G
G
R
N
D
Y
R
N
D
Q
R
N
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation