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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GCN5-like 2
Full Name:
Histone acetyltransferase KAT2A
Alias:
GCN5; GCN5L2; GCNL2; General control of amino acid synthesis protein 5-like 2; HGCN5; Histone acetyltransferase GCN5; K (lysine) acetyltransferase 2A; PCAF-b; STAF97
Type:
EC 2.3.1.48; Acetyltransferase
Mass (Da):
93836
Number AA:
837
UniProt ID:
Q92830
International Prot ID:
IPI00306871
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030914
GO:0033276
Uniprot
OncoNet
Molecular Function:
GO:0004402
GO:0042826
GO:0003713
PhosphoSite+
KinaseNET
Biological Process:
GO:0006338
GO:0043966
GO:0016578
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T9
A
E
P
S
Q
A
P
T
P
A
P
A
A
Q
P
Site 2
S21
A
Q
P
R
P
L
Q
S
P
A
P
A
P
T
P
Site 3
T27
Q
S
P
A
P
A
P
T
P
T
P
A
P
S
P
Site 4
T29
P
A
P
A
P
T
P
T
P
A
P
S
P
A
S
Site 5
S33
P
T
P
T
P
A
P
S
P
A
S
A
P
I
P
Site 6
S36
T
P
A
P
S
P
A
S
A
P
I
P
T
P
T
Site 7
T41
P
A
S
A
P
I
P
T
P
T
P
A
P
A
P
Site 8
T43
S
A
P
I
P
T
P
T
P
A
P
A
P
A
P
Site 9
S67
T
G
G
P
G
V
G
S
G
G
A
G
S
G
G
Site 10
S72
V
G
S
G
G
A
G
S
G
G
D
P
A
R
P
Site 11
S82
D
P
A
R
P
G
L
S
Q
Q
Q
R
A
S
Q
Site 12
S88
L
S
Q
Q
Q
R
A
S
Q
R
K
A
Q
V
R
Site 13
T130
W
K
N
P
K
P
P
T
A
P
R
M
D
L
Q
Site 14
S144
Q
Q
P
A
A
N
L
S
E
L
C
R
S
C
E
Site 15
S149
N
L
S
E
L
C
R
S
C
E
H
P
L
A
D
Site 16
S159
H
P
L
A
D
H
V
S
H
L
E
N
V
S
E
Site 17
S185
D
V
E
N
L
F
M
S
V
H
K
E
E
D
T
Site 18
T192
S
V
H
K
E
E
D
T
D
T
K
Q
V
Y
F
Site 19
T194
H
K
E
E
D
T
D
T
K
Q
V
Y
F
Y
L
Site 20
Y198
D
T
D
T
K
Q
V
Y
F
Y
L
F
K
L
L
Site 21
Y200
D
T
K
Q
V
Y
F
Y
L
F
K
L
L
R
K
Site 22
S220
T
R
P
V
V
E
G
S
L
G
S
P
P
F
E
Site 23
S223
V
V
E
G
S
L
G
S
P
P
F
E
K
P
N
Site 24
T253
L
A
P
R
E
R
Q
T
M
F
E
L
S
K
M
Site 25
T272
L
N
Y
W
K
L
E
T
P
A
Q
F
R
Q
R
Site 26
S280
P
A
Q
F
R
Q
R
S
Q
A
E
D
V
A
T
Site 27
T287
S
Q
A
E
D
V
A
T
Y
K
V
N
Y
T
R
Site 28
S307
H
V
P
Q
S
C
D
S
L
P
R
Y
E
T
T
Site 29
Y311
S
C
D
S
L
P
R
Y
E
T
T
H
V
F
G
Site 30
T313
D
S
L
P
R
Y
E
T
T
H
V
F
G
R
S
Site 31
S324
F
G
R
S
L
L
R
S
I
F
T
V
T
R
R
Site 32
T329
L
R
S
I
F
T
V
T
R
R
Q
L
L
E
K
Site 33
T354
E
K
R
T
L
I
L
T
H
F
P
K
F
L
S
Site 34
S361
T
H
F
P
K
F
L
S
M
L
E
E
E
I
Y
Site 35
Y368
S
M
L
E
E
E
I
Y
G
A
N
S
P
I
W
Site 36
S372
E
E
I
Y
G
A
N
S
P
I
W
E
S
G
F
Site 37
S377
A
N
S
P
I
W
E
S
G
F
T
M
P
P
S
Site 38
T380
P
I
W
E
S
G
F
T
M
P
P
S
E
G
T
Site 39
S384
S
G
F
T
M
P
P
S
E
G
T
Q
L
V
P
Site 40
S408
V
P
S
T
P
I
F
S
P
S
M
G
G
G
S
Site 41
S410
S
T
P
I
F
S
P
S
M
G
G
G
S
N
S
Site 42
S415
S
P
S
M
G
G
G
S
N
S
S
L
S
L
D
Site 43
S417
S
M
G
G
G
S
N
S
S
L
S
L
D
S
A
Site 44
S418
M
G
G
G
S
N
S
S
L
S
L
D
S
A
G
Site 45
S420
G
G
S
N
S
S
L
S
L
D
S
A
G
A
E
Site 46
S423
N
S
S
L
S
L
D
S
A
G
A
E
P
M
P
Site 47
T435
P
M
P
G
E
K
R
T
L
P
E
N
L
T
L
Site 48
T441
R
T
L
P
E
N
L
T
L
E
D
A
K
R
L
Site 49
T489
A
N
A
A
R
D
E
T
A
R
L
E
E
R
R
Site 50
S507
E
F
H
V
I
G
N
S
L
T
P
K
A
N
R
Site 51
T509
H
V
I
G
N
S
L
T
P
K
A
N
R
R
V
Site 52
S528
V
G
L
Q
N
V
F
S
H
Q
L
P
R
M
P
Site 53
Y538
L
P
R
M
P
K
E
Y
I
A
R
L
V
F
D
Site 54
T550
V
F
D
P
K
H
K
T
L
A
L
I
K
D
G
Site 55
Y609
H
I
K
H
N
I
L
Y
F
L
T
Y
A
D
E
Site 56
Y617
F
L
T
Y
A
D
E
Y
A
I
G
Y
F
K
K
Site 57
Y621
A
D
E
Y
A
I
G
Y
F
K
K
Q
G
F
S
Site 58
S636
K
D
I
K
V
P
K
S
R
Y
L
G
Y
I
K
Site 59
Y645
Y
L
G
Y
I
K
D
Y
E
G
A
T
L
M
E
Site 60
Y661
E
L
N
P
R
I
P
Y
T
E
L
S
H
I
I
Site 61
T662
L
N
P
R
I
P
Y
T
E
L
S
H
I
I
K
Site 62
S665
R
I
P
Y
T
E
L
S
H
I
I
K
K
Q
K
Site 63
Y690
Q
A
Q
I
R
K
V
Y
P
G
L
S
C
F
K
Site 64
S694
R
K
V
Y
P
G
L
S
C
F
K
E
G
V
R
Site 65
T714
S
V
P
G
I
R
E
T
G
W
K
P
L
G
K
Site 66
Y734
L
K
D
P
D
Q
L
Y
T
T
L
K
N
L
L
Site 67
T736
D
P
D
Q
L
Y
T
T
L
K
N
L
L
A
Q
Site 68
S746
N
L
L
A
Q
I
K
S
H
P
S
A
W
P
F
Site 69
Y765
K
K
S
E
A
P
D
Y
Y
E
V
I
R
F
P
Site 70
Y766
K
S
E
A
P
D
Y
Y
E
V
I
R
F
P
I
Site 71
T777
R
F
P
I
D
L
K
T
M
T
E
R
L
R
S
Site 72
T779
P
I
D
L
K
T
M
T
E
R
L
R
S
R
Y
Site 73
S784
T
M
T
E
R
L
R
S
R
Y
Y
V
T
R
K
Site 74
Y786
T
E
R
L
R
S
R
Y
Y
V
T
R
K
L
F
Site 75
Y787
E
R
L
R
S
R
Y
Y
V
T
R
K
L
F
V
Site 76
Y807
V
I
A
N
C
R
E
Y
N
P
P
D
S
E
Y
Site 77
S812
R
E
Y
N
P
P
D
S
E
Y
C
R
C
A
S
Site 78
Y814
Y
N
P
P
D
S
E
Y
C
R
C
A
S
A
L
Site 79
Y826
S
A
L
E
K
F
F
Y
F
K
L
K
E
G
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation