KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
NELL1
Full Name:
Protein kinase C-binding protein NELL1
Alias:
FLJ45906; IDH3GL; Isocitrate dehydrogenase 3 gamma-like; NEL-like 1; Neural epidermal growth; NRP1; Protein kinase C-binding protein NELL1
Type:
Secreted protein
Mass (Da):
89607
Number AA:
810
UniProt ID:
Q92832
International Prot ID:
IPI00023754
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005576
Uniprot
OncoNet
Molecular Function:
GO:0005509
GO:0005198
PhosphoSite+
KinaseNET
Biological Process:
GO:0007155
GO:0007399
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S55
V
S
G
M
H
N
A
S
K
A
F
L
F
Q
D
Site 2
T92
S
E
F
T
I
L
A
T
V
Q
Q
K
P
S
T
Site 3
S100
V
Q
Q
K
P
S
T
S
G
V
I
L
S
I
R
Site 4
S105
S
T
S
G
V
I
L
S
I
R
E
L
E
H
S
Site 5
S112
S
I
R
E
L
E
H
S
Y
F
E
L
E
S
S
Site 6
Y113
I
R
E
L
E
H
S
Y
F
E
L
E
S
S
G
Site 7
S119
S
Y
F
E
L
E
S
S
G
L
R
D
E
I
R
Site 8
Y127
G
L
R
D
E
I
R
Y
H
Y
I
H
N
G
K
Site 9
Y129
R
D
E
I
R
Y
H
Y
I
H
N
G
K
P
R
Site 10
Y142
P
R
T
E
A
L
P
Y
R
M
A
D
G
Q
W
Site 11
Y171
H
V
D
C
N
R
I
Y
E
R
V
I
D
P
P
Site 12
T180
R
V
I
D
P
P
D
T
N
L
P
P
G
I
N
Site 13
T229
N
L
N
H
T
C
P
T
C
S
D
F
L
S
L
Site 14
Y280
C
Q
V
S
G
L
L
Y
R
D
Q
D
S
W
V
Site 15
T296
G
D
H
C
R
N
C
T
C
K
S
G
A
V
E
Site 16
S308
A
V
E
C
R
R
M
S
C
P
P
L
N
C
S
Site 17
S315
S
C
P
P
L
N
C
S
P
D
S
L
P
V
H
Site 18
T350
A
E
G
Q
R
I
L
T
K
S
C
R
E
C
R
Site 19
S352
G
Q
R
I
L
T
K
S
C
R
E
C
R
G
G
Site 20
Y422
T
C
E
C
K
S
G
Y
I
S
V
Q
G
D
S
Site 21
S424
E
C
K
S
G
Y
I
S
V
Q
G
D
S
A
Y
Site 22
Y431
S
V
Q
G
D
S
A
Y
C
E
D
I
D
E
C
Site 23
Y466
R
C
D
C
V
P
G
Y
I
R
V
D
D
F
S
Site 24
T503
T
V
Q
G
H
S
C
T
C
K
P
G
Y
V
G
Site 25
Y525
F
C
E
E
G
C
R
Y
G
G
T
C
V
A
P
Site 26
S544
C
P
S
G
F
T
G
S
H
C
E
K
D
I
D
Site 27
T586
S
G
F
H
D
D
G
T
Y
S
L
S
G
E
S
Site 28
Y587
G
F
H
D
D
G
T
Y
S
L
S
G
E
S
C
Site 29
S588
F
H
D
D
G
T
Y
S
L
S
G
E
S
C
I
Site 30
S590
D
D
G
T
Y
S
L
S
G
E
S
C
I
D
I
Site 31
T606
E
C
A
L
R
T
H
T
C
W
N
D
S
A
C
Site 32
S626
G
F
D
C
L
C
P
S
G
P
S
C
S
G
D
Site 33
S631
C
P
S
G
P
S
C
S
G
D
C
P
H
E
G
Site 34
S655
T
L
K
E
D
R
C
S
V
C
S
C
K
D
G
Site 35
T691
P
E
C
D
T
R
V
T
S
Q
C
L
D
Q
N
Site 36
S692
E
C
D
T
R
V
T
S
Q
C
L
D
Q
N
G
Site 37
Y703
D
Q
N
G
H
K
L
Y
R
S
G
D
N
W
T
Site 38
T738
P
N
L
S
C
E
Y
T
A
I
L
E
G
E
C
Site 39
T760
P
C
L
A
D
N
I
T
Y
D
I
R
K
T
C
Site 40
T766
I
T
Y
D
I
R
K
T
C
L
D
S
Y
G
V
Site 41
S770
I
R
K
T
C
L
D
S
Y
G
V
S
R
L
S
Site 42
Y771
R
K
T
C
L
D
S
Y
G
V
S
R
L
S
G
Site 43
T782
R
L
S
G
S
V
W
T
M
A
G
S
P
C
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation