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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DDX17
Full Name:
Probable ATP-dependent RNA helicase DDX17
Alias:
DEAD box protein 17; DEAD box protein p72; RNA-dependent helicase p72
Type:
Nucleus protein
Mass (Da):
72371
Number AA:
650
UniProt ID:
Q92841
International Prot ID:
IPI00023785
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0043226
GO:0043227
Uniprot
OncoNet
Molecular Function:
GO:0000166
GO:0003676
GO:0003723
PhosphoSite+
KinaseNET
Biological Process:
GO:0006139
GO:0006396
GO:0008152
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S46
R
K
K
K
W
D
L
S
E
L
P
K
F
E
K
Site 2
Y56
P
K
F
E
K
N
F
Y
V
E
H
P
E
V
A
Site 3
T66
H
P
E
V
A
R
L
T
P
Y
E
V
D
E
L
Site 4
Y68
E
V
A
R
L
T
P
Y
E
V
D
E
L
R
R
Site 5
T80
L
R
R
K
K
E
I
T
V
R
G
G
D
V
C
Site 6
Y102
H
H
A
N
F
P
Q
Y
V
M
D
V
L
M
D
Site 7
T116
D
Q
H
F
T
E
P
T
P
I
Q
C
Q
G
F
Site 8
S140
V
G
I
A
Q
T
G
S
G
K
T
L
A
Y
L
Site 9
Y159
V
H
I
N
H
Q
P
Y
L
E
R
G
D
G
P
Site 10
Y188
V
Q
Q
V
A
D
D
Y
G
K
C
S
R
L
K
Site 11
S192
A
D
D
Y
G
K
C
S
R
L
K
S
T
C
I
Site 12
S196
G
K
C
S
R
L
K
S
T
C
I
Y
G
G
A
Site 13
Y200
R
L
K
S
T
C
I
Y
G
G
A
P
K
G
P
Site 14
T222
G
V
E
I
C
I
A
T
P
G
R
L
I
D
F
Site 15
T235
D
F
L
E
S
G
K
T
N
L
R
R
C
T
Y
Site 16
T241
K
T
N
L
R
R
C
T
Y
L
V
L
D
E
A
Site 17
Y242
T
N
L
R
R
C
T
Y
L
V
L
D
E
A
D
Site 18
T279
Q
T
L
M
W
S
A
T
W
P
K
E
V
R
Q
Site 19
Y295
A
E
D
F
L
R
D
Y
T
Q
I
N
V
G
N
Site 20
T296
E
D
F
L
R
D
Y
T
Q
I
N
V
G
N
L
Site 21
S306
N
V
G
N
L
E
L
S
A
N
H
N
I
L
Q
Site 22
T348
K
T
I
I
F
V
E
T
K
R
R
C
D
D
L
Site 23
T356
K
R
R
C
D
D
L
T
R
R
M
R
R
D
G
Site 24
S374
M
C
I
H
G
D
K
S
Q
P
E
R
D
W
V
Site 25
Y414
D
V
K
F
V
I
N
Y
D
Y
P
N
S
S
E
Site 26
Y416
K
F
V
I
N
Y
D
Y
P
N
S
S
E
D
Y
Site 27
Y423
Y
P
N
S
S
E
D
Y
V
H
R
I
G
R
T
Site 28
S433
R
I
G
R
T
A
R
S
T
N
K
G
T
A
Y
Site 29
T434
I
G
R
T
A
R
S
T
N
K
G
T
A
Y
T
Site 30
Y440
S
T
N
K
G
T
A
Y
T
F
F
T
P
G
N
Site 31
T441
T
N
K
G
T
A
Y
T
F
F
T
P
G
N
L
Site 32
T444
G
T
A
Y
T
F
F
T
P
G
N
L
K
Q
A
Site 33
S486
G
G
G
G
G
G
R
S
R
Y
R
T
T
S
S
Site 34
Y488
G
G
G
G
R
S
R
Y
R
T
T
S
S
A
N
Site 35
T490
G
G
R
S
R
Y
R
T
T
S
S
A
N
N
P
Site 36
T491
G
R
S
R
Y
R
T
T
S
S
A
N
N
P
N
Site 37
S492
R
S
R
Y
R
T
T
S
S
A
N
N
P
N
L
Site 38
S493
S
R
Y
R
T
T
S
S
A
N
N
P
N
L
M
Site 39
Y501
A
N
N
P
N
L
M
Y
Q
D
E
C
D
R
R
Site 40
S520
K
D
G
G
R
R
D
S
A
S
Y
R
D
R
S
Site 41
S522
G
G
R
R
D
S
A
S
Y
R
D
R
S
E
T
Site 42
Y523
G
R
R
D
S
A
S
Y
R
D
R
S
E
T
D
Site 43
S527
S
A
S
Y
R
D
R
S
E
T
D
R
A
G
Y
Site 44
T529
S
Y
R
D
R
S
E
T
D
R
A
G
Y
A
N
Site 45
Y534
S
E
T
D
R
A
G
Y
A
N
G
S
G
Y
G
Site 46
S538
R
A
G
Y
A
N
G
S
G
Y
G
S
P
N
S
Site 47
Y540
G
Y
A
N
G
S
G
Y
G
S
P
N
S
A
F
Site 48
S542
A
N
G
S
G
Y
G
S
P
N
S
A
F
G
A
Site 49
S545
S
G
Y
G
S
P
N
S
A
F
G
A
Q
A
G
Site 50
Y554
F
G
A
Q
A
G
Q
Y
T
Y
G
Q
G
T
Y
Site 51
S570
A
A
A
Y
G
T
S
S
Y
T
A
Q
E
Y
G
Site 52
Y576
S
S
Y
T
A
Q
E
Y
G
A
G
T
Y
G
A
Site 53
S584
G
A
G
T
Y
G
A
S
S
T
T
S
T
G
R
Site 54
S585
A
G
T
Y
G
A
S
S
T
T
S
T
G
R
S
Site 55
S588
Y
G
A
S
S
T
T
S
T
G
R
S
S
Q
S
Site 56
T589
G
A
S
S
T
T
S
T
G
R
S
S
Q
S
S
Site 57
S592
S
T
T
S
T
G
R
S
S
Q
S
S
S
Q
Q
Site 58
S593
T
T
S
T
G
R
S
S
Q
S
S
S
Q
Q
F
Site 59
S595
S
T
G
R
S
S
Q
S
S
S
Q
Q
F
S
G
Site 60
S596
T
G
R
S
S
Q
S
S
S
Q
Q
F
S
G
I
Site 61
S597
G
R
S
S
Q
S
S
S
Q
Q
F
S
G
I
G
Site 62
S601
Q
S
S
S
Q
Q
F
S
G
I
G
R
S
G
Q
Site 63
S615
Q
Q
P
Q
P
L
M
S
Q
Q
F
A
Q
P
P
Site 64
Y636
G
Y
M
G
Q
T
A
Y
Q
Y
P
P
P
P
P
Site 65
Y638
M
G
Q
T
A
Y
Q
Y
P
P
P
P
P
P
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation