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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NEO1
Full Name:
Neogenin
Alias:
HsT17534; IGDCC2; Immunoglobulin superfamily DCC subclass member 2; Immunoglobulin superfamily, DCC subclass, member 2; Neogenin; Neogenin 1; NGN
Type:
Receptor, misc.
Mass (Da):
160017
Number AA:
1461
UniProt ID:
Q92859
International Prot ID:
IPI00023814
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005887
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0007155
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S12
R
G
A
R
R
L
L
S
T
P
S
F
W
L
Y
Site 2
T51
G
A
S
I
R
T
F
T
P
F
Y
F
L
V
E
Site 3
Y164
Q
P
E
P
S
S
V
Y
A
G
N
N
A
I
L
Site 4
S256
L
V
F
L
K
Q
P
S
P
L
V
R
V
I
G
Site 5
Y548
P
A
P
N
L
R
A
Y
A
A
S
P
T
S
I
Site 6
Y572
G
N
G
E
I
Q
N
Y
K
L
Y
Y
M
E
K
Site 7
Y602
T
I
N
G
L
K
K
Y
T
E
Y
S
F
R
V
Site 8
T603
I
N
G
L
K
K
Y
T
E
Y
S
F
R
V
V
Site 9
Y891
K
I
T
D
S
R
Y
Y
T
V
R
W
K
T
N
Site 10
Y905
N
I
P
A
N
T
K
Y
K
N
A
N
A
T
T
Site 11
Y915
A
N
A
T
T
L
S
Y
L
V
T
G
L
K
P
Site 12
T955
T
T
F
E
L
V
P
T
S
P
P
K
D
V
T
Site 13
S956
T
F
E
L
V
P
T
S
P
P
K
D
V
T
V
Site 14
S1056
F
R
T
P
K
A
D
S
S
D
K
M
P
N
D
Site 15
S1057
R
T
P
K
A
D
S
S
D
K
M
P
N
D
Q
Site 16
S1066
K
M
P
N
D
Q
A
S
G
S
G
G
K
G
S
Site 17
S1068
P
N
D
Q
A
S
G
S
G
G
K
G
S
R
L
Site 18
T1131
A
V
F
C
T
R
R
T
T
S
H
Q
K
K
K
Site 19
T1132
V
F
C
T
R
R
T
T
S
H
Q
K
K
K
R
Site 20
S1133
F
C
T
R
R
T
T
S
H
Q
K
K
K
R
A
Site 21
S1144
K
K
R
A
A
C
K
S
V
N
G
S
H
K
Y
Site 22
S1148
A
C
K
S
V
N
G
S
H
K
Y
K
G
N
S
Site 23
Y1151
S
V
N
G
S
H
K
Y
K
G
N
S
K
D
V
Site 24
S1178
E
L
K
P
I
D
K
S
P
D
P
N
P
I
M
Site 25
T1186
P
D
P
N
P
I
M
T
D
T
P
I
P
R
N
Site 26
T1188
P
N
P
I
M
T
D
T
P
I
P
R
N
S
Q
Site 27
S1194
D
T
P
I
P
R
N
S
Q
D
I
T
P
V
D
Site 28
T1198
P
R
N
S
Q
D
I
T
P
V
D
N
S
M
D
Site 29
S1203
D
I
T
P
V
D
N
S
M
D
S
N
I
H
Q
Site 30
S1206
P
V
D
N
S
M
D
S
N
I
H
Q
R
R
N
Site 31
S1214
N
I
H
Q
R
R
N
S
Y
R
G
H
E
S
E
Site 32
Y1215
I
H
Q
R
R
N
S
Y
R
G
H
E
S
E
D
Site 33
S1220
N
S
Y
R
G
H
E
S
E
D
S
M
S
T
L
Site 34
S1223
R
G
H
E
S
E
D
S
M
S
T
L
A
G
R
Site 35
S1225
H
E
S
E
D
S
M
S
T
L
A
G
R
R
G
Site 36
S1243
K
M
M
M
P
F
D
S
Q
P
P
Q
P
V
I
Site 37
S1251
Q
P
P
Q
P
V
I
S
A
H
P
I
H
S
L
Site 38
S1267
N
P
H
H
H
F
H
S
S
S
L
A
S
P
A
Site 39
S1268
P
H
H
H
F
H
S
S
S
L
A
S
P
A
R
Site 40
S1269
H
H
H
F
H
S
S
S
L
A
S
P
A
R
S
Site 41
S1272
F
H
S
S
S
L
A
S
P
A
R
S
H
L
Y
Site 42
S1276
S
L
A
S
P
A
R
S
H
L
Y
H
P
G
S
Site 43
Y1279
S
P
A
R
S
H
L
Y
H
P
G
S
P
W
P
Site 44
S1283
S
H
L
Y
H
P
G
S
P
W
P
I
G
T
S
Site 45
T1289
G
S
P
W
P
I
G
T
S
M
S
L
S
D
R
Site 46
S1290
S
P
W
P
I
G
T
S
M
S
L
S
D
R
A
Site 47
S1292
W
P
I
G
T
S
M
S
L
S
D
R
A
N
S
Site 48
S1294
I
G
T
S
M
S
L
S
D
R
A
N
S
T
E
Site 49
S1299
S
L
S
D
R
A
N
S
T
E
S
V
R
N
T
Site 50
T1300
L
S
D
R
A
N
S
T
E
S
V
R
N
T
P
Site 51
S1302
D
R
A
N
S
T
E
S
V
R
N
T
P
S
T
Site 52
T1306
S
T
E
S
V
R
N
T
P
S
T
D
T
M
P
Site 53
S1308
E
S
V
R
N
T
P
S
T
D
T
M
P
A
S
Site 54
T1309
S
V
R
N
T
P
S
T
D
T
M
P
A
S
S
Site 55
T1311
R
N
T
P
S
T
D
T
M
P
A
S
S
S
Q
Site 56
S1315
S
T
D
T
M
P
A
S
S
S
Q
T
C
C
T
Site 57
S1317
D
T
M
P
A
S
S
S
Q
T
C
C
T
D
H
Site 58
T1322
S
S
S
Q
T
C
C
T
D
H
Q
D
P
E
G
Site 59
S1332
Q
D
P
E
G
A
T
S
S
S
Y
L
A
S
S
Site 60
S1333
D
P
E
G
A
T
S
S
S
Y
L
A
S
S
Q
Site 61
S1334
P
E
G
A
T
S
S
S
Y
L
A
S
S
Q
E
Site 62
Y1335
E
G
A
T
S
S
S
Y
L
A
S
S
Q
E
E
Site 63
S1338
T
S
S
S
Y
L
A
S
S
Q
E
E
D
S
G
Site 64
S1339
S
S
S
Y
L
A
S
S
Q
E
E
D
S
G
Q
Site 65
S1344
A
S
S
Q
E
E
D
S
G
Q
S
L
P
T
A
Site 66
T1350
D
S
G
Q
S
L
P
T
A
H
V
R
P
S
H
Site 67
S1356
P
T
A
H
V
R
P
S
H
P
L
K
S
F
A
Site 68
S1361
R
P
S
H
P
L
K
S
F
A
V
P
A
I
P
Site 69
T1374
I
P
P
P
G
P
P
T
Y
D
P
A
L
P
S
Site 70
Y1375
P
P
P
G
P
P
T
Y
D
P
A
L
P
S
T
Site 71
S1381
T
Y
D
P
A
L
P
S
T
P
L
L
S
Q
Q
Site 72
T1382
Y
D
P
A
L
P
S
T
P
L
L
S
Q
Q
A
Site 73
S1386
L
P
S
T
P
L
L
S
Q
Q
A
L
N
H
H
Site 74
S1396
A
L
N
H
H
I
H
S
V
K
T
A
S
I
G
Site 75
T1404
V
K
T
A
S
I
G
T
L
G
R
S
R
P
P
Site 76
S1408
S
I
G
T
L
G
R
S
R
P
P
M
P
V
V
Site 77
T1425
S
A
P
E
V
Q
E
T
T
R
M
L
E
D
S
Site 78
S1432
T
T
R
M
L
E
D
S
E
S
S
Y
E
P
D
Site 79
S1434
R
M
L
E
D
S
E
S
S
Y
E
P
D
E
L
Site 80
S1435
M
L
E
D
S
E
S
S
Y
E
P
D
E
L
T
Site 81
Y1436
L
E
D
S
E
S
S
Y
E
P
D
E
L
T
K
Site 82
T1442
S
Y
E
P
D
E
L
T
K
E
M
A
H
L
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation