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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CDS1
Full Name:
Phosphatidate cytidylyltransferase 1
Alias:
CDP-DAG synthase 1; CDP-DG synthetase 1; CDP-diacylglycerol synthase 1; CDP-diglyceride pyrophosphorylase 1; CDP-diglyceride synthetase 1; CDS 1; CTP:phosphatidate cytidylyltransferase 1; EC 2.7.7.41
Type:
Enzyme - Synthetase. Phospholipid synthesis.
Mass (Da):
53304
Number AA:
461
UniProt ID:
Q92903
International Prot ID:
IPI00024234
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0004142
GO:0000287
GO:0004605
PhosphoSite+
KinaseNET
Biological Process:
GO:0008654
GO:0007165
GO:0007601
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
L
E
L
R
H
R
G
S
C
P
G
P
R
E
A
Site 2
S18
P
G
P
R
E
A
V
S
P
P
H
R
E
G
E
Site 3
T33
A
A
G
G
D
H
E
T
E
S
T
S
D
K
E
Site 4
S35
G
G
D
H
E
T
E
S
T
S
D
K
E
T
D
Site 5
T36
G
D
H
E
T
E
S
T
S
D
K
E
T
D
I
Site 6
S37
D
H
E
T
E
S
T
S
D
K
E
T
D
I
D
Site 7
T41
E
S
T
S
D
K
E
T
D
I
D
D
R
Y
G
Site 8
Y47
E
T
D
I
D
D
R
Y
G
D
L
D
S
R
T
Site 9
S52
D
R
Y
G
D
L
D
S
R
T
D
S
D
I
P
Site 10
T54
Y
G
D
L
D
S
R
T
D
S
D
I
P
E
I
Site 11
S56
D
L
D
S
R
T
D
S
D
I
P
E
I
P
P
Site 12
S64
D
I
P
E
I
P
P
S
S
D
R
T
P
E
I
Site 13
S65
I
P
E
I
P
P
S
S
D
R
T
P
E
I
L
Site 14
T68
I
P
P
S
S
D
R
T
P
E
I
L
K
K
A
Site 15
S77
E
I
L
K
K
A
L
S
G
L
S
S
R
W
K
Site 16
Y134
I
T
I
G
Y
R
V
Y
H
S
Y
D
L
P
W
Site 17
Y137
G
Y
R
V
Y
H
S
Y
D
L
P
W
F
R
T
Site 18
Y165
Y
G
E
T
V
A
D
Y
F
A
T
F
V
Q
R
Site 19
T168
T
V
A
D
Y
F
A
T
F
V
Q
R
E
E
Q
Site 20
Y207
L
S
L
V
K
K
H
Y
R
L
Q
F
Y
M
F
Site 21
S272
R
T
P
L
I
K
L
S
P
K
K
T
W
E
G
Site 22
T276
I
K
L
S
P
K
K
T
W
E
G
F
I
G
G
Site 23
S286
G
F
I
G
G
F
F
S
T
V
V
F
G
F
I
Site 24
S312
V
C
P
V
E
Y
R
S
D
V
N
S
F
V
T
Site 25
S316
E
Y
R
S
D
V
N
S
F
V
T
E
C
E
P
Site 26
S324
F
V
T
E
C
E
P
S
E
L
F
Q
L
Q
T
Site 27
Y332
E
L
F
Q
L
Q
T
Y
S
L
P
P
F
L
K
Site 28
S348
V
L
R
Q
E
R
V
S
L
Y
P
F
Q
I
H
Site 29
Y350
R
Q
E
R
V
S
L
Y
P
F
Q
I
H
S
I
Site 30
S424
F
I
R
G
P
N
P
S
K
V
L
Q
Q
L
L
Site 31
Y442
P
E
Q
Q
L
N
I
Y
K
T
L
K
T
H
L
Site 32
T444
Q
Q
L
N
I
Y
K
T
L
K
T
H
L
I
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation