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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
EXTL1
Full Name:
Exostosin-like 1
Alias:
Exostosin-L;Glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase;Multiple exostosis-like protein
Type:
Mass (Da):
74697
Number AA:
676
UniProt ID:
Q92935
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
Q
S
W
R
R
R
K
S
L
W
L
A
L
S
A
Site 2
S43
P
R
P
R
P
G
A
S
Q
G
W
P
R
W
L
Site 3
S57
L
D
A
E
L
L
Q
S
F
S
Q
P
G
E
L
Site 4
S59
A
E
L
L
Q
S
F
S
Q
P
G
E
L
P
E
Site 5
S70
E
L
P
E
D
A
V
S
P
P
Q
A
P
H
G
Site 6
S108
Y
P
A
V
G
T
I
S
E
T
H
R
R
I
L
Site 7
T110
A
V
G
T
I
S
E
T
H
R
R
I
L
A
S
Site 8
S117
T
H
R
R
I
L
A
S
I
E
G
S
R
F
Y
Site 9
Y124
S
I
E
G
S
R
F
Y
T
F
S
P
A
G
A
Site 10
T143
L
L
S
L
D
A
Q
T
G
E
C
S
S
M
P
Site 11
T172
H
P
A
P
C
P
R
T
F
Q
L
G
Q
A
M
Site 12
S184
Q
A
M
V
A
E
A
S
P
T
V
D
S
F
R
Site 13
T186
M
V
A
E
A
S
P
T
V
D
S
F
R
P
G
Site 14
S189
E
A
S
P
T
V
D
S
F
R
P
G
F
D
V
Site 15
S219
P
G
Q
L
R
Q
H
S
P
Q
P
G
V
A
L
Site 16
T238
E
E
R
G
G
W
R
T
A
D
T
G
S
S
A
Site 17
T241
G
G
W
R
T
A
D
T
G
S
S
A
C
P
W
Site 18
T266
G
Q
T
Q
R
Q
E
T
L
P
N
A
T
F
C
Site 19
T271
Q
E
T
L
P
N
A
T
F
C
L
I
S
G
H
Site 20
S284
G
H
R
P
E
A
A
S
R
F
L
Q
A
L
Q
Site 21
Y354
T
Q
F
L
W
D
A
Y
F
S
S
V
E
K
V
Site 22
S377
Q
D
R
I
F
G
T
S
A
H
P
S
L
L
W
Site 23
S381
F
G
T
S
A
H
P
S
L
L
W
N
S
P
P
Site 24
S400
A
L
S
T
F
S
T
S
P
Q
D
F
P
F
Y
Site 25
Y407
S
P
Q
D
F
P
F
Y
Y
L
Q
Q
G
S
R
Site 26
Y408
P
Q
D
F
P
F
Y
Y
L
Q
Q
G
S
R
P
Site 27
S420
S
R
P
E
G
R
F
S
A
L
I
W
V
G
P
Site 28
S453
A
Q
I
L
V
L
W
S
N
E
R
P
L
P
S
Site 29
S460
S
N
E
R
P
L
P
S
R
W
P
E
T
A
V
Site 30
T470
P
E
T
A
V
P
L
T
V
I
D
G
H
R
K
Site 31
S479
I
D
G
H
R
K
V
S
D
R
F
Y
P
Y
S
Site 32
Y483
R
K
V
S
D
R
F
Y
P
Y
S
T
I
R
T
Site 33
S486
S
D
R
F
Y
P
Y
S
T
I
R
T
D
A
I
Site 34
T487
D
R
F
Y
P
Y
S
T
I
R
T
D
A
I
L
Site 35
T490
Y
P
Y
S
T
I
R
T
D
A
I
L
S
L
D
Site 36
S501
L
S
L
D
A
R
S
S
L
S
T
S
E
V
D
Site 37
S503
L
D
A
R
S
S
L
S
T
S
E
V
D
F
A
Site 38
T504
D
A
R
S
S
L
S
T
S
E
V
D
F
A
F
Site 39
T526
E
R
M
V
G
F
L
T
S
S
H
F
W
D
E
Site 40
S549
A
E
R
T
N
E
F
S
M
V
L
T
T
A
A
Site 41
T553
N
E
F
S
M
V
L
T
T
A
A
F
Y
H
R
Site 42
Y562
A
A
F
Y
H
R
Y
Y
H
T
L
F
T
H
S
Site 43
S649
F
G
H
M
P
L
L
S
S
R
L
R
L
D
P
Site 44
S664
V
L
F
K
D
P
V
S
V
Q
R
K
K
Y
R
Site 45
Y670
V
S
V
Q
R
K
K
Y
R
S
L
E
K
P
_
Site 46
S672
V
Q
R
K
K
Y
R
S
L
E
K
P
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation