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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
HEAB
Full Name:
Polyribonucleotide 5'-hydroxyl-kinase Clp1
Alias:
ATP/GTPbinding protein; ATP/GTP-binding protein; ATP_GTP binding protein; CLP1; CLP1, cleavage and polyadenylation factor I subunit,; Pre-mRNA cleavage complex II protein Clp1
Type:
RNA binding protein
Mass (Da):
47646
Number AA:
125
UniProt ID:
Q92989
International Prot ID:
IPI00024381
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0000214
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0046404
GO:0051736
PhosphoSite+
KinaseNET
Biological Process:
GO:0031124
GO:0000398
GO:0035087
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T21
K
F
E
L
E
R
E
T
E
L
R
F
E
V
E
Site 2
S30
L
R
F
E
V
E
A
S
Q
S
V
Q
L
E
L
Site 3
S32
F
E
V
E
A
S
Q
S
V
Q
L
E
L
L
T
Site 4
T47
G
M
A
E
I
F
G
T
E
L
T
R
N
K
K
Site 5
T56
L
T
R
N
K
K
F
T
F
D
A
G
A
K
V
Site 6
S76
H
G
C
S
V
Q
L
S
G
R
T
E
V
A
Y
Site 7
Y83
S
G
R
T
E
V
A
Y
V
S
K
D
T
P
M
Site 8
Y93
K
D
T
P
M
L
L
Y
L
N
T
H
T
A
L
Site 9
T146
V
R
L
G
R
R
P
T
Y
V
E
L
D
V
G
Site 10
Y147
R
L
G
R
R
P
T
Y
V
E
L
D
V
G
Q
Site 11
Y167
P
G
T
M
G
A
L
Y
I
E
R
P
A
D
V
Site 12
S190
P
L
V
Y
H
F
G
S
T
T
P
G
T
N
I
Site 13
T192
V
Y
H
F
G
S
T
T
P
G
T
N
I
K
L
Site 14
T195
F
G
S
T
T
P
G
T
N
I
K
L
Y
N
K
Site 15
Y200
P
G
T
N
I
K
L
Y
N
K
I
T
S
R
L
Site 16
Y263
V
L
D
Q
E
R
L
Y
N
E
L
K
R
D
L
Site 17
S282
R
T
V
L
L
P
K
S
G
G
V
V
E
R
S
Site 18
S289
S
G
G
V
V
E
R
S
K
D
F
R
R
E
C
Site 19
Y304
R
D
E
R
I
R
E
Y
F
Y
G
F
R
G
C
Site 20
Y306
E
R
I
R
E
Y
F
Y
G
F
R
G
C
F
Y
Site 21
S344
S
C
L
P
L
G
M
S
Q
E
D
N
Q
L
K
Site 22
T356
Q
L
K
L
V
P
V
T
P
G
R
D
M
V
H
Site 23
S369
V
H
H
L
L
S
V
S
T
A
E
G
T
E
E
Site 24
S379
E
G
T
E
E
N
L
S
E
T
S
V
A
G
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation