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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LPP
Full Name:
Lipoma-preferred partner
Alias:
LIM domain containing preferred translocation partner in lipoma; LIPOMA PREFERRED partner
Type:
Cytoskeletal protein, adapter/scaffold protein
Mass (Da):
65746
Number AA:
612
UniProt ID:
Q93052
International Prot ID:
IPI00023704
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005925
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0007155
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
P
S
W
L
P
P
K
S
T
G
E
P
L
G
H
Site 2
T12
S
W
L
P
P
K
S
T
G
E
P
L
G
H
V
Site 3
T25
H
V
P
A
R
M
E
T
T
H
S
F
G
N
P
Site 4
S28
A
R
M
E
T
T
H
S
F
G
N
P
S
I
S
Site 5
S33
T
H
S
F
G
N
P
S
I
S
V
S
T
Q
Q
Site 6
S35
S
F
G
N
P
S
I
S
V
S
T
Q
Q
P
P
Site 7
S37
G
N
P
S
I
S
V
S
T
Q
Q
P
P
K
K
Site 8
Y55
V
V
A
P
K
P
K
Y
N
P
Y
K
Q
P
G
Site 9
Y58
P
K
P
K
Y
N
P
Y
K
Q
P
G
G
E
G
Site 10
S78
P
P
P
P
L
D
D
S
S
A
L
P
S
I
S
Site 11
S79
P
P
P
L
D
D
S
S
A
L
P
S
I
S
G
Site 12
S83
D
D
S
S
A
L
P
S
I
S
G
N
F
P
P
Site 13
S85
S
S
A
L
P
S
I
S
G
N
F
P
P
P
P
Site 14
T109
Q
G
N
P
G
G
K
T
L
E
E
R
R
S
S
Site 15
S115
K
T
L
E
E
R
R
S
S
L
D
A
E
I
D
Site 16
S116
T
L
E
E
R
R
S
S
L
D
A
E
I
D
S
Site 17
S126
A
E
I
D
S
L
T
S
I
L
A
D
L
E
C
Site 18
S134
I
L
A
D
L
E
C
S
S
P
Y
K
P
R
P
Site 19
S135
L
A
D
L
E
C
S
S
P
Y
K
P
R
P
P
Site 20
S144
Y
K
P
R
P
P
Q
S
S
T
G
S
T
A
S
Site 21
S145
K
P
R
P
P
Q
S
S
T
G
S
T
A
S
P
Site 22
T146
P
R
P
P
Q
S
S
T
G
S
T
A
S
P
P
Site 23
S148
P
P
Q
S
S
T
G
S
T
A
S
P
P
V
S
Site 24
T149
P
Q
S
S
T
G
S
T
A
S
P
P
V
S
T
Site 25
S151
S
S
T
G
S
T
A
S
P
P
V
S
T
P
V
Site 26
S155
S
T
A
S
P
P
V
S
T
P
V
T
G
H
K
Site 27
T156
T
A
S
P
P
V
S
T
P
V
T
G
H
K
R
Site 28
T159
P
P
V
S
T
P
V
T
G
H
K
R
M
V
I
Site 29
T173
I
P
N
Q
P
P
L
T
A
T
K
K
S
T
L
Site 30
T175
N
Q
P
P
L
T
A
T
K
K
S
T
L
K
P
Site 31
T179
L
T
A
T
K
K
S
T
L
K
P
Q
P
A
P
Site 32
T198
I
P
V
A
P
I
G
T
L
K
P
Q
P
Q
P
Site 33
S209
Q
P
Q
P
V
P
A
S
Y
T
T
A
S
T
S
Site 34
Y210
P
Q
P
V
P
A
S
Y
T
T
A
S
T
S
S
Site 35
T211
Q
P
V
P
A
S
Y
T
T
A
S
T
S
S
R
Site 36
T212
P
V
P
A
S
Y
T
T
A
S
T
S
S
R
P
Site 37
S214
P
A
S
Y
T
T
A
S
T
S
S
R
P
T
F
Site 38
S216
S
Y
T
T
A
S
T
S
S
R
P
T
F
N
V
Site 39
T220
A
S
T
S
S
R
P
T
F
N
V
Q
V
K
S
Site 40
S227
T
F
N
V
Q
V
K
S
A
Q
P
S
P
H
Y
Site 41
S231
Q
V
K
S
A
Q
P
S
P
H
Y
M
A
A
P
Site 42
Y234
S
A
Q
P
S
P
H
Y
M
A
A
P
S
S
G
Site 43
S239
P
H
Y
M
A
A
P
S
S
G
Q
I
Y
G
S
Site 44
S240
H
Y
M
A
A
P
S
S
G
Q
I
Y
G
S
G
Site 45
Y244
A
P
S
S
G
Q
I
Y
G
S
G
P
Q
G
Y
Site 46
S246
S
S
G
Q
I
Y
G
S
G
P
Q
G
Y
N
T
Site 47
Y251
Y
G
S
G
P
Q
G
Y
N
T
Q
P
V
P
V
Site 48
T253
S
G
P
Q
G
Y
N
T
Q
P
V
P
V
S
G
Site 49
S259
N
T
Q
P
V
P
V
S
G
Q
C
P
P
P
S
Site 50
S266
S
G
Q
C
P
P
P
S
T
R
G
G
M
D
Y
Site 51
Y273
S
T
R
G
G
M
D
Y
A
Y
I
P
P
P
G
Site 52
Y275
R
G
G
M
D
Y
A
Y
I
P
P
P
G
L
Q
Site 53
Y287
G
L
Q
P
E
P
G
Y
G
Y
A
P
N
Q
G
Site 54
Y289
Q
P
E
P
G
Y
G
Y
A
P
N
Q
G
R
Y
Site 55
Y296
Y
A
P
N
Q
G
R
Y
Y
E
G
Y
Y
A
A
Site 56
Y297
A
P
N
Q
G
R
Y
Y
E
G
Y
Y
A
A
G
Site 57
Y300
Q
G
R
Y
Y
E
G
Y
Y
A
A
G
P
G
Y
Site 58
Y301
G
R
Y
Y
E
G
Y
Y
A
A
G
P
G
Y
G
Site 59
Y307
Y
Y
A
A
G
P
G
Y
G
G
R
N
D
S
D
Site 60
S313
G
Y
G
G
R
N
D
S
D
P
T
Y
G
Q
Q
Site 61
T316
G
R
N
D
S
D
P
T
Y
G
Q
Q
G
H
P
Site 62
Y317
R
N
D
S
D
P
T
Y
G
Q
Q
G
H
P
N
Site 63
T325
G
Q
Q
G
H
P
N
T
W
K
R
E
P
G
Y
Site 64
Y332
T
W
K
R
E
P
G
Y
T
P
P
G
A
G
N
Site 65
T333
W
K
R
E
P
G
Y
T
P
P
G
A
G
N
Q
Site 66
Y346
N
Q
N
P
P
G
M
Y
P
V
T
G
P
K
K
Site 67
T349
P
P
G
M
Y
P
V
T
G
P
K
K
T
Y
I
Site 68
T357
G
P
K
K
T
Y
I
T
D
P
V
S
A
P
C
Site 69
S375
L
Q
P
K
G
G
H
S
G
Q
L
G
P
S
S
Site 70
S381
H
S
G
Q
L
G
P
S
S
V
A
P
S
F
R
Site 71
S382
S
G
Q
L
G
P
S
S
V
A
P
S
F
R
P
Site 72
S386
G
P
S
S
V
A
P
S
F
R
P
E
D
E
L
Site 73
T397
E
D
E
L
E
H
L
T
K
K
M
L
Y
D
M
Site 74
Y402
H
L
T
K
K
M
L
Y
D
M
E
N
P
P
A
Site 75
Y412
E
N
P
P
A
D
E
Y
F
G
R
C
A
R
C
Site 76
Y457
K
L
R
G
Q
P
F
Y
A
V
E
K
K
A
Y
Site 77
Y464
Y
A
V
E
K
K
A
Y
C
E
P
C
Y
I
N
Site 78
Y469
K
A
Y
C
E
P
C
Y
I
N
T
L
E
Q
C
Site 79
T491
M
E
R
I
L
R
A
T
G
K
A
Y
H
P
H
Site 80
S537
K
K
F
A
P
R
C
S
V
C
K
E
P
I
M
Site 81
T552
P
A
P
G
Q
E
E
T
V
R
I
V
A
L
D
Site 82
Y567
R
D
F
H
V
H
C
Y
R
C
E
D
C
G
G
Site 83
S577
E
D
C
G
G
L
L
S
E
G
D
N
Q
G
C
Site 84
Y585
E
G
D
N
Q
G
C
Y
P
L
D
G
H
I
L
Site 85
T595
D
G
H
I
L
C
K
T
C
N
S
A
R
I
R
Site 86
S609
R
V
L
T
A
K
A
S
T
D
L
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation