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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KIAA0256
Full Name:
Selenocysteine insertion sequence-binding protein 2-like
Alias:
K0256; kiaa0256; Protein; SECIS binding protein 2-like
Type:
Unknown function
Mass (Da):
121776
Number AA:
1101
UniProt ID:
Q93073
International Prot ID:
IPI00004067
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T6
_
_
M
D
R
A
P
T
E
Q
N
V
K
L
S
Site 2
S25
P
F
I
P
Q
K
K
S
P
D
T
F
M
I
P
Site 3
T28
P
Q
K
K
S
P
D
T
F
M
I
P
M
A
L
Site 4
S41
A
L
P
N
D
N
G
S
V
S
G
V
E
P
T
Site 5
S43
P
N
D
N
G
S
V
S
G
V
E
P
T
P
I
Site 6
Y58
P
S
Y
L
I
T
C
Y
P
F
V
Q
E
N
Q
Site 7
Y73
S
N
R
Q
F
P
L
Y
N
N
D
I
R
W
Q
Site 8
Y90
N
P
N
P
T
G
P
Y
F
A
Y
P
I
I
S
Site 9
Y93
P
T
G
P
Y
F
A
Y
P
I
I
S
A
Q
P
Site 10
S103
I
S
A
Q
P
P
V
S
T
E
Y
T
Y
Y
Q
Site 11
T107
P
P
V
S
T
E
Y
T
Y
Y
Q
L
M
P
A
Site 12
Y108
P
V
S
T
E
Y
T
Y
Y
Q
L
M
P
A
P
Site 13
Y109
V
S
T
E
Y
T
Y
Y
Q
L
M
P
A
P
C
Site 14
T148
N
A
I
T
T
E
C
T
E
R
P
S
Q
L
G
Site 15
S152
T
E
C
T
E
R
P
S
Q
L
G
Q
V
F
P
Site 16
S161
L
G
Q
V
F
P
L
S
S
H
R
S
R
N
S
Site 17
S162
G
Q
V
F
P
L
S
S
H
R
S
R
N
S
N
Site 18
S165
F
P
L
S
S
H
R
S
R
N
S
N
R
G
S
Site 19
S168
S
S
H
R
S
R
N
S
N
R
G
S
V
V
P
Site 20
S172
S
R
N
S
N
R
G
S
V
V
P
K
Q
Q
L
Site 21
S186
L
L
Q
Q
H
I
K
S
K
R
P
L
V
K
N
Site 22
S207
T
N
A
A
G
P
D
S
R
S
K
I
V
L
L
Site 23
T221
L
V
D
A
S
Q
Q
T
D
F
P
S
D
I
A
Site 24
S225
S
Q
Q
T
D
F
P
S
D
I
A
N
K
S
L
Site 25
S231
P
S
D
I
A
N
K
S
L
S
E
T
T
A
T
Site 26
S233
D
I
A
N
K
S
L
S
E
T
T
A
T
M
L
Site 27
T235
A
N
K
S
L
S
E
T
T
A
T
M
L
W
K
Site 28
T238
S
L
S
E
T
T
A
T
M
L
W
K
S
K
G
Site 29
S243
T
A
T
M
L
W
K
S
K
G
R
R
R
R
A
Site 30
S251
K
G
R
R
R
R
A
S
H
P
T
A
E
S
S
Site 31
T254
R
R
R
A
S
H
P
T
A
E
S
S
S
E
Q
Site 32
S257
A
S
H
P
T
A
E
S
S
S
E
Q
G
A
S
Site 33
S258
S
H
P
T
A
E
S
S
S
E
Q
G
A
S
E
Site 34
S259
H
P
T
A
E
S
S
S
E
Q
G
A
S
E
A
Site 35
S264
S
S
S
E
Q
G
A
S
E
A
D
I
D
S
D
Site 36
S270
A
S
E
A
D
I
D
S
D
S
G
Y
C
S
P
Site 37
S272
E
A
D
I
D
S
D
S
G
Y
C
S
P
K
H
Site 38
Y274
D
I
D
S
D
S
G
Y
C
S
P
K
H
S
N
Site 39
S276
D
S
D
S
G
Y
C
S
P
K
H
S
N
N
Q
Site 40
S280
G
Y
C
S
P
K
H
S
N
N
Q
P
A
A
G
Site 41
S294
G
A
L
R
N
P
D
S
G
T
M
N
H
V
E
Site 42
T296
L
R
N
P
D
S
G
T
M
N
H
V
E
S
S
Site 43
T330
P
W
M
E
K
N
Q
T
F
S
R
G
G
R
Q
Site 44
T338
F
S
R
G
G
R
Q
T
E
Q
R
N
N
S
Q
Site 45
S344
Q
T
E
Q
R
N
N
S
Q
V
G
F
R
C
R
Site 46
S354
G
F
R
C
R
G
H
S
T
S
S
E
R
R
Q
Site 47
S356
R
C
R
G
H
S
T
S
S
E
R
R
Q
N
L
Site 48
S357
C
R
G
H
S
T
S
S
E
R
R
Q
N
L
Q
Site 49
S373
R
P
D
N
K
H
L
S
S
S
Q
S
H
R
S
Site 50
S375
D
N
K
H
L
S
S
S
Q
S
H
R
S
D
P
Site 51
S377
K
H
L
S
S
S
Q
S
H
R
S
D
P
N
S
Site 52
S380
S
S
S
Q
S
H
R
S
D
P
N
S
E
S
L
Site 53
S384
S
H
R
S
D
P
N
S
E
S
L
Y
F
E
D
Site 54
S386
R
S
D
P
N
S
E
S
L
Y
F
E
D
E
D
Site 55
Y388
D
P
N
S
E
S
L
Y
F
E
D
E
D
G
F
Site 56
S414
E
N
I
Q
Q
K
L
S
S
K
V
L
D
D
L
Site 57
S425
L
D
D
L
P
E
N
S
P
I
N
I
V
Q
T
Site 58
S439
T
P
I
P
I
T
T
S
V
P
K
R
A
K
S
Site 59
S446
S
V
P
K
R
A
K
S
Q
K
K
K
A
L
A
Site 60
T486
A
A
G
K
K
N
K
T
P
V
Q
L
D
L
G
Site 61
T512
A
M
K
A
R
Q
I
T
N
T
R
P
L
S
Y
Site 62
T514
K
A
R
Q
I
T
N
T
R
P
L
S
Y
T
V
Site 63
S526
Y
T
V
V
T
A
A
S
F
H
T
K
D
S
T
Site 64
S532
A
S
F
H
T
K
D
S
T
N
R
K
P
L
T
Site 65
T533
S
F
H
T
K
D
S
T
N
R
K
P
L
T
K
Site 66
T539
S
T
N
R
K
P
L
T
K
S
Q
P
C
L
T
Site 67
S541
N
R
K
P
L
T
K
S
Q
P
C
L
T
S
F
Site 68
T546
T
K
S
Q
P
C
L
T
S
F
N
S
V
D
I
Site 69
S547
K
S
Q
P
C
L
T
S
F
N
S
V
D
I
A
Site 70
S550
P
C
L
T
S
F
N
S
V
D
I
A
S
S
K
Site 71
S556
N
S
V
D
I
A
S
S
K
A
K
K
G
K
E
Site 72
T591
E
E
K
K
G
R
L
T
V
D
H
N
L
L
G
Site 73
S599
V
D
H
N
L
L
G
S
E
E
P
T
E
M
H
Site 74
T603
L
L
G
S
E
E
P
T
E
M
H
L
D
F
I
Site 75
S619
D
L
P
Q
E
I
V
S
Q
E
D
T
G
L
S
Site 76
T623
E
I
V
S
Q
E
D
T
G
L
S
M
P
S
D
Site 77
S626
S
Q
E
D
T
G
L
S
M
P
S
D
T
S
L
Site 78
S629
D
T
G
L
S
M
P
S
D
T
S
L
S
P
A
Site 79
S632
L
S
M
P
S
D
T
S
L
S
P
A
S
Q
N
Site 80
S634
M
P
S
D
T
S
L
S
P
A
S
Q
N
S
P
Site 81
S637
D
T
S
L
S
P
A
S
Q
N
S
P
Y
C
M
Site 82
S640
L
S
P
A
S
Q
N
S
P
Y
C
M
T
P
V
Site 83
Y642
P
A
S
Q
N
S
P
Y
C
M
T
P
V
S
Q
Site 84
T645
Q
N
S
P
Y
C
M
T
P
V
S
Q
G
S
P
Site 85
S648
P
Y
C
M
T
P
V
S
Q
G
S
P
A
S
S
Site 86
S651
M
T
P
V
S
Q
G
S
P
A
S
S
G
I
G
Site 87
S654
V
S
Q
G
S
P
A
S
S
G
I
G
S
P
M
Site 88
S655
S
Q
G
S
P
A
S
S
G
I
G
S
P
M
A
Site 89
S664
I
G
S
P
M
A
S
S
T
I
T
K
I
H
S
Site 90
T665
G
S
P
M
A
S
S
T
I
T
K
I
H
S
K
Site 91
T667
P
M
A
S
S
T
I
T
K
I
H
S
K
R
F
Site 92
Y677
H
S
K
R
F
R
E
Y
C
N
Q
V
L
C
K
Site 93
Y705
V
S
F
Q
E
R
I
Y
Q
K
D
P
V
R
A
Site 94
T726
V
M
G
L
R
E
V
T
K
H
M
K
L
N
K
Site 95
Y818
T
E
E
A
R
K
A
Y
K
D
M
V
A
A
M
Site 96
S847
V
P
H
H
M
G
H
S
R
N
P
S
A
A
S
Site 97
S851
M
G
H
S
R
N
P
S
A
A
S
A
I
S
F
Site 98
S867
S
V
I
S
E
P
I
S
E
V
N
E
K
E
Y
Site 99
Y874
S
E
V
N
E
K
E
Y
E
T
N
W
R
N
M
Site 100
T884
N
W
R
N
M
V
E
T
S
D
G
L
E
A
S
Site 101
S891
T
S
D
G
L
E
A
S
E
N
E
K
E
V
S
Site 102
S898
S
E
N
E
K
E
V
S
C
K
H
S
T
S
E
Site 103
S902
K
E
V
S
C
K
H
S
T
S
E
K
P
S
K
Site 104
S904
V
S
C
K
H
S
T
S
E
K
P
S
K
L
P
Site 105
S908
H
S
T
S
E
K
P
S
K
L
P
F
D
T
P
Site 106
T914
P
S
K
L
P
F
D
T
P
P
I
G
K
Q
P
Site 107
S922
P
P
I
G
K
Q
P
S
L
V
A
T
G
S
T
Site 108
T926
K
Q
P
S
L
V
A
T
G
S
T
T
S
A
T
Site 109
S934
G
S
T
T
S
A
T
S
A
G
K
S
T
A
S
Site 110
S938
S
A
T
S
A
G
K
S
T
A
S
D
K
E
E
Site 111
S941
S
A
G
K
S
T
A
S
D
K
E
E
V
K
P
Site 112
S955
P
D
D
L
E
W
A
S
Q
Q
S
T
E
T
G
Site 113
S958
L
E
W
A
S
Q
Q
S
T
E
T
G
S
L
D
Site 114
T959
E
W
A
S
Q
Q
S
T
E
T
G
S
L
D
G
Site 115
S963
Q
Q
S
T
E
T
G
S
L
D
G
S
C
R
D
Site 116
S967
E
T
G
S
L
D
G
S
C
R
D
L
L
N
S
Site 117
S974
S
C
R
D
L
L
N
S
S
I
T
S
T
T
S
Site 118
S975
C
R
D
L
L
N
S
S
I
T
S
T
T
S
T
Site 119
Y1002
D
E
E
E
E
E
D
Y
T
H
E
P
I
S
V
Site 120
T1003
E
E
E
E
E
D
Y
T
H
E
P
I
S
V
E
Site 121
S1008
D
Y
T
H
E
P
I
S
V
E
V
Q
L
N
S
Site 122
S1015
S
V
E
V
Q
L
N
S
R
I
E
S
W
V
S
Site 123
S1019
Q
L
N
S
R
I
E
S
W
V
S
E
T
Q
R
Site 124
S1022
S
R
I
E
S
W
V
S
E
T
Q
R
T
M
E
Site 125
T1024
I
E
S
W
V
S
E
T
Q
R
T
M
E
T
L
Site 126
T1027
W
V
S
E
T
Q
R
T
M
E
T
L
Q
L
G
Site 127
T1036
E
T
L
Q
L
G
K
T
L
N
G
S
E
E
D
Site 128
S1040
L
G
K
T
L
N
G
S
E
E
D
N
V
E
Q
Site 129
T1069
G
M
D
S
E
A
W
T
A
D
Q
Q
A
S
P
Site 130
S1075
W
T
A
D
Q
Q
A
S
P
G
Q
Q
K
S
S
Site 131
S1081
A
S
P
G
Q
Q
K
S
S
N
C
S
S
L
N
Site 132
S1082
S
P
G
Q
Q
K
S
S
N
C
S
S
L
N
K
Site 133
S1085
Q
Q
K
S
S
N
C
S
S
L
N
K
E
H
S
Site 134
S1086
Q
K
S
S
N
C
S
S
L
N
K
E
H
S
D
Site 135
S1092
S
S
L
N
K
E
H
S
D
S
N
Y
T
T
Q
Site 136
S1094
L
N
K
E
H
S
D
S
N
Y
T
T
Q
T
T
Site 137
Y1096
K
E
H
S
D
S
N
Y
T
T
Q
T
T
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation