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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ATP2A3
Full Name:
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3
Alias:
AT2A3; Calcium pump 3; EC 3.6.3.8; SERCA3; SR Ca(2 )-ATPase 3
Type:
Sarcoplasmic reticulum membrane, Nuclear membrane, Membrane, Nucleus, Integral membrane protein
Mass (Da):
113977
Number AA:
1043
UniProt ID:
Q93084
International Prot ID:
IPI00748794
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
GO:0005634
GO:0016529
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0005509
GO:0005388
PhosphoSite+
KinaseNET
Biological Process:
GO:0006754
GO:0006816
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y36
V
T
G
A
R
E
R
Y
G
P
N
E
L
P
S
Site 2
S43
Y
G
P
N
E
L
P
S
E
E
G
K
S
L
W
Site 3
S48
L
P
S
E
E
G
K
S
L
W
E
L
V
L
E
Site 4
T84
W
F
E
E
G
E
E
T
T
T
A
F
V
E
P
Site 5
T86
E
E
G
E
E
T
T
T
A
F
V
E
P
L
V
Site 6
Y122
A
I
E
A
L
K
E
Y
E
P
E
M
G
K
V
Site 7
S132
E
M
G
K
V
I
R
S
D
R
K
G
V
Q
R
Site 8
S170
L
R
L
I
E
I
K
S
T
T
L
R
V
D
Q
Site 9
T171
R
L
I
E
I
K
S
T
T
L
R
V
D
Q
S
Site 10
S178
T
T
L
R
V
D
Q
S
I
L
T
G
E
S
V
Site 11
T181
R
V
D
Q
S
I
L
T
G
E
S
V
S
V
T
Site 12
S184
Q
S
I
L
T
G
E
S
V
S
V
T
K
H
T
Site 13
S186
I
L
T
G
E
S
V
S
V
T
K
H
T
E
A
Site 14
T188
T
G
E
S
V
S
V
T
K
H
T
E
A
I
P
Site 15
S210
D
K
K
N
M
L
F
S
G
T
N
I
T
S
G
Site 16
T212
K
N
M
L
F
S
G
T
N
I
T
S
G
K
A
Site 17
T226
A
V
G
V
A
V
A
T
G
L
H
T
E
L
G
Site 18
T230
A
V
A
T
G
L
H
T
E
L
G
K
I
R
S
Site 19
S237
T
E
L
G
K
I
R
S
Q
M
A
A
V
E
P
Site 20
T247
A
A
V
E
P
E
R
T
P
L
Q
R
K
L
D
Site 21
S287
A
D
P
A
H
G
G
S
W
L
R
G
A
V
Y
Site 22
S335
R
K
N
A
I
V
R
S
L
P
S
V
E
T
L
Site 23
T353
S
V
I
C
S
D
K
T
G
T
L
T
T
N
Q
Site 24
T357
S
D
K
T
G
T
L
T
T
N
Q
M
S
V
C
Site 25
S385
L
L
H
E
F
T
I
S
G
T
T
Y
T
P
E
Site 26
Y389
F
T
I
S
G
T
T
Y
T
P
E
G
E
V
R
Site 27
T390
T
I
S
G
T
T
Y
T
P
E
G
E
V
R
Q
Site 28
Y427
C
N
D
S
A
L
D
Y
N
E
A
K
G
V
Y
Site 29
Y434
Y
N
E
A
K
G
V
Y
E
K
V
G
E
A
T
Site 30
T441
Y
E
K
V
G
E
A
T
E
T
A
L
T
C
L
Site 31
T446
E
A
T
E
T
A
L
T
C
L
V
E
K
M
N
Site 32
T457
E
K
M
N
V
F
D
T
D
L
Q
A
L
S
R
Site 33
T473
E
R
A
G
A
C
N
T
V
I
K
Q
L
M
R
Site 34
T484
Q
L
M
R
K
E
F
T
L
E
F
S
R
D
R
Site 35
S488
K
E
F
T
L
E
F
S
R
D
R
K
S
M
S
Site 36
S493
E
F
S
R
D
R
K
S
M
S
V
Y
C
T
P
Site 37
S495
S
R
D
R
K
S
M
S
V
Y
C
T
P
T
R
Site 38
Y497
D
R
K
S
M
S
V
Y
C
T
P
T
R
P
H
Site 39
T499
K
S
M
S
V
Y
C
T
P
T
R
P
H
P
T
Site 40
S510
P
H
P
T
G
Q
G
S
K
M
F
V
K
G
A
Site 41
S520
F
V
K
G
A
P
E
S
V
I
E
R
C
S
S
Site 42
S526
E
S
V
I
E
R
C
S
S
V
R
V
G
S
R
Site 43
S527
S
V
I
E
R
C
S
S
V
R
V
G
S
R
T
Site 44
S532
C
S
S
V
R
V
G
S
R
T
A
P
L
T
P
Site 45
T534
S
V
R
V
G
S
R
T
A
P
L
T
P
T
S
Site 46
T538
G
S
R
T
A
P
L
T
P
T
S
R
E
Q
I
Site 47
S541
T
A
P
L
T
P
T
S
R
E
Q
I
L
A
K
Site 48
S554
A
K
I
R
D
W
G
S
G
S
D
T
L
R
C
Site 49
T558
D
W
G
S
G
S
D
T
L
R
C
L
A
L
A
Site 50
T645
R
L
G
I
F
G
D
T
E
D
V
A
G
K
A
Site 51
S662
G
R
E
F
D
D
L
S
P
E
Q
Q
R
Q
A
Site 52
T672
Q
Q
R
Q
A
C
R
T
A
R
C
F
A
R
V
Site 53
S685
R
V
E
P
A
H
K
S
R
I
V
E
N
L
Q
Site 54
S693
R
I
V
E
N
L
Q
S
F
N
E
I
T
A
M
Site 55
Y754
V
E
E
G
R
A
I
Y
S
N
M
K
Q
F
I
Site 56
Y763
N
M
K
Q
F
I
R
Y
L
I
S
S
N
V
G
Site 57
S823
I
M
E
K
L
P
R
S
P
R
E
A
L
I
S
Site 58
S830
S
P
R
E
A
L
I
S
G
W
L
F
F
R
Y
Site 59
Y868
E
G
P
H
I
N
F
Y
Q
L
R
N
F
L
K
Site 60
S915
E
M
C
N
A
L
N
S
V
S
E
N
Q
S
L
Site 61
S917
C
N
A
L
N
S
V
S
E
N
Q
S
L
L
R
Site 62
S921
N
S
V
S
E
N
Q
S
L
L
R
M
P
P
W
Site 63
Y986
L
L
D
E
A
L
K
Y
L
S
R
N
H
M
H
Site 64
T1003
L
Y
P
G
L
L
R
T
V
S
Q
A
W
S
R
Site 65
S1005
P
G
L
L
R
T
V
S
Q
A
W
S
R
Q
P
Site 66
S1009
R
T
V
S
Q
A
W
S
R
Q
P
L
T
T
S
Site 67
T1014
A
W
S
R
Q
P
L
T
T
S
W
T
P
D
H
Site 68
T1015
W
S
R
Q
P
L
T
T
S
W
T
P
D
H
T
Site 69
S1016
S
R
Q
P
L
T
T
S
W
T
P
D
H
T
G
Site 70
T1018
Q
P
L
T
T
S
W
T
P
D
H
T
G
R
N
Site 71
T1022
T
S
W
T
P
D
H
T
G
R
N
E
P
E
V
Site 72
S1037
S
A
G
N
R
V
E
S
P
V
C
T
S
D
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation