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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NKD1
Full Name:
Protein naked cuticle homolog 1
Alias:
Type:
Mass (Da):
52285
Number AA:
470
UniProt ID:
Q969G9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S17
A
V
C
K
R
R
E
S
P
E
G
D
S
F
A
Site 2
S22
R
E
S
P
E
G
D
S
F
A
V
S
A
A
W
Site 3
S26
E
G
D
S
F
A
V
S
A
A
W
A
R
K
G
Site 4
S48
Q
R
C
P
G
G
V
S
G
P
R
Q
L
R
L
Site 5
T58
R
Q
L
R
L
A
G
T
I
G
R
S
T
R
E
Site 6
S62
L
A
G
T
I
G
R
S
T
R
E
L
V
G
D
Site 7
T63
A
G
T
I
G
R
S
T
R
E
L
V
G
D
V
Site 8
T74
V
G
D
V
L
R
D
T
L
S
E
E
E
E
D
Site 9
S76
D
V
L
R
D
T
L
S
E
E
E
E
D
D
F
Site 10
T94
V
A
L
P
P
E
K
T
D
G
L
G
S
G
D
Site 11
S109
E
K
K
M
E
R
V
S
E
P
C
P
G
S
K
Site 12
S115
V
S
E
P
C
P
G
S
K
K
Q
L
K
F
E
Site 13
S129
E
E
L
Q
C
D
V
S
M
E
E
D
S
R
Q
Site 14
S134
D
V
S
M
E
E
D
S
R
Q
E
W
T
F
T
Site 15
Y143
Q
E
W
T
F
T
L
Y
D
F
D
N
N
G
K
Site 16
S158
V
T
R
E
D
I
T
S
L
L
H
T
I
Y
E
Site 17
S169
T
I
Y
E
V
V
D
S
S
V
N
H
S
P
T
Site 18
S170
I
Y
E
V
V
D
S
S
V
N
H
S
P
T
S
Site 19
S174
V
D
S
S
V
N
H
S
P
T
S
S
K
M
L
Site 20
T176
S
S
V
N
H
S
P
T
S
S
K
M
L
R
V
Site 21
S177
S
V
N
H
S
P
T
S
S
K
M
L
R
V
K
Site 22
S178
V
N
H
S
P
T
S
S
K
M
L
R
V
K
L
Site 23
T186
K
M
L
R
V
K
L
T
V
A
P
D
G
S
Q
Site 24
S192
L
T
V
A
P
D
G
S
Q
S
K
R
S
V
L
Site 25
S194
V
A
P
D
G
S
Q
S
K
R
S
V
L
V
N
Site 26
S197
D
G
S
Q
S
K
R
S
V
L
V
N
Q
A
D
Site 27
S207
V
N
Q
A
D
L
Q
S
A
R
P
R
A
E
T
Site 28
T214
S
A
R
P
R
A
E
T
K
P
T
E
D
L
R
Site 29
T217
P
R
A
E
T
K
P
T
E
D
L
R
S
W
E
Site 30
S222
K
P
T
E
D
L
R
S
W
E
K
K
Q
R
A
Site 31
S237
P
L
R
F
Q
G
D
S
R
L
E
Q
S
G
C
Site 32
Y245
R
L
E
Q
S
G
C
Y
H
H
C
V
D
E
N
Site 33
Y259
N
I
E
R
R
N
H
Y
L
D
L
A
G
I
E
Site 34
Y268
D
L
A
G
I
E
N
Y
T
S
Q
F
G
P
G
Site 35
S270
A
G
I
E
N
Y
T
S
Q
F
G
P
G
S
P
Site 36
S276
T
S
Q
F
G
P
G
S
P
S
V
A
Q
K
S
Site 37
S278
Q
F
G
P
G
S
P
S
V
A
Q
K
S
E
L
Site 38
S283
S
P
S
V
A
Q
K
S
E
L
P
P
R
T
S
Site 39
T289
K
S
E
L
P
P
R
T
S
N
P
T
R
S
R
Site 40
S290
S
E
L
P
P
R
T
S
N
P
T
R
S
R
S
Site 41
T293
P
P
R
T
S
N
P
T
R
S
R
S
H
E
P
Site 42
S295
R
T
S
N
P
T
R
S
R
S
H
E
P
E
A
Site 43
S297
S
N
P
T
R
S
R
S
H
E
P
E
A
I
H
Site 44
S317
P
Q
G
V
D
P
A
S
F
H
F
L
D
T
P
Site 45
T338
L
Q
Q
R
L
R
G
T
Q
D
G
S
K
H
F
Site 46
S348
G
S
K
H
F
V
R
S
P
K
A
Q
G
K
S
Site 47
S355
S
P
K
A
Q
G
K
S
V
G
V
G
H
V
A
Site 48
S409
H
K
H
R
A
K
E
S
Q
Q
G
C
R
G
L
Site 49
Y441
E
L
P
A
L
V
V
Y
E
S
Q
A
G
Q
P
Site 50
S443
P
A
L
V
V
Y
E
S
Q
A
G
Q
P
V
Q
Site 51
Y468
H
H
H
Y
H
H
F
Y
Q
T
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation