PhosphoNET

           
Protein Info 
   
Short Name:  CNKSR1
Full Name:  Connector enhancer of kinase suppressor of ras 1
Alias:  CNK homolog protein 1; Connector enhancer of KSR-like
Type:  Adaptor/scaffold, G protein regulator, misc.
Mass (Da):  79706
Number AA:  720
UniProt ID:  Q969H4
International Prot ID:  IPI00299824
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005938  GO:0005911  GO:0019898 Uniprot OncoNet
Molecular Function:  GO:0030674     PhosphoSite+ KinaseNET
Biological Process:  GO:0007266  GO:0007169   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T8MEPVETWTPGKVATW
Site 2S22WLRGLDDSLQDYPFE
Site 3Y26LDDSLQDYPFEDWQL
Site 4S71VEQLQALSSRLQTEN
Site 5T76ALSSRLQTENLQSLT
Site 6S81LQTENLQSLTEGLLG
Site 7S154RDLLEELSQVLHEDG
Site 8T169PAAEKEGTVLRICSH
Site 9S206LEQVQLDSPLGLEIH
Site 10S223SNCQHFVSQVDTQVP
Site 11T227HFVSQVDTQVPTDSR
Site 12S278LREPAGLSLVLKKIP
Site 13T289KKIPIPETPPQTPPQ
Site 14T293IPETPPQTPPQVLDS
Site 15S300TPPQVLDSPHQRSPS
Site 16S305LDSPHQRSPSLSLAP
Site 17S307SPHQRSPSLSLAPLS
Site 18S309HQRSPSLSLAPLSPR
Site 19S314SLSLAPLSPRAPSED
Site 20S319PLSPRAPSEDVFAFD
Site 21S328DVFAFDLSSNPSPGP
Site 22S329VFAFDLSSNPSPGPS
Site 23S332FDLSSNPSPGPSPAW
Site 24S336SNPSPGPSPAWTDSA
Site 25T340PGPSPAWTDSASLGP
Site 26S342PSPAWTDSASLGPEP
Site 27S344PAWTDSASLGPEPLP
Site 28S373GTPGLPESPDKSPVG
Site 29S377LPESPDKSPVGRKKS
Site 30S384SPVGRKKSKGLATRL
Site 31S392KGLATRLSRRRVSCR
Site 32S397RLSRRRVSCRELGRP
Site 33Y437VLKGHTLYWYRQPQD
Site 34Y439KGHTLYWYRQPQDEK
Site 35S454AEGLINVSNYSLESG
Site 36Y456GLINVSNYSLESGHD
Site 37S457LINVSNYSLESGHDQ
Site 38Y468GHDQKKKYVFQLTHD
Site 39T473KKYVFQLTHDVYKPF
Site 40S502RHLITCISKYQSPGR
Site 41Y504LITCISKYQSPGRAP
Site 42S506TCISKYQSPGRAPPP
Site 43Y519PPREEDCYSETEAED
Site 44S520PREEDCYSETEAEDP
Site 45S533DPDDEAGSHSASPSP
Site 46S535DDEAGSHSASPSPAQ
Site 47S537EAGSHSASPSPAQAG
Site 48S539GSHSASPSPAQAGSP
Site 49S545PSPAQAGSPLHGDTS
Site 50S552SPLHGDTSPAATPTQ
Site 51T556GDTSPAATPTQRSPR
Site 52T558TSPAATPTQRSPRTS
Site 53S561AATPTQRSPRTSFGS
Site 54T564PTQRSPRTSFGSLTD
Site 55S565TQRSPRTSFGSLTDS
Site 56S568SPRTSFGSLTDSSEE
Site 57T570RTSFGSLTDSSEEAL
Site 58S572SFGSLTDSSEEALEG
Site 59S573FGSLTDSSEEALEGM
Site 60S590GLRQGGVSLLGQPQP
Site 61T599LGQPQPLTQEQWRSS
Site 62S605LTQEQWRSSFMRRNR
Site 63S606TQEQWRSSFMRRNRD
Site 64T629RVRALQSTLKAKLQE
Site 65Y665KEQNRELYSEGLGAW
Site 66S666EQNRELYSEGLGAWG
Site 67S680GVAQAEGSSHILTSD
Site 68T685EGSSHILTSDSTEQS
Site 69S686GSSHILTSDSTEQSP
Site 70S688SHILTSDSTEQSPHS
Site 71T689HILTSDSTEQSPHSL
Site 72S692TSDSTEQSPHSLPSD
Site 73S695STEQSPHSLPSDPEE
Site 74S698QSPHSLPSDPEEHSH
Site 75S704PSDPEEHSHLCPLTS
Site 76T710HSHLCPLTSESSLRP
Site 77S711SHLCPLTSESSLRPP
Site 78S714CPLTSESSLRPPDL_
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


2019 Kinexus Bioinformatics Corporation