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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZKSCAN4
Full Name:
Zinc finger protein with KRAB and SCAN domains 4
Alias:
Zinc finger protein 307
Type:
Mass (Da):
61579
Number AA:
545
UniProt ID:
Q969J2
International Prot ID:
IPI00005191
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003700
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0006355
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T24
E
D
Q
T
G
L
L
T
V
K
V
E
K
E
E
Site 2
S44
A
E
V
R
A
P
C
S
P
A
R
G
P
E
R
Site 3
S52
P
A
R
G
P
E
R
S
R
Q
R
F
R
G
F
Site 4
Y61
Q
R
F
R
G
F
R
Y
P
E
A
A
G
P
R
Site 5
S72
A
G
P
R
E
A
L
S
R
L
R
E
L
C
G
Site 6
S111
I
L
P
G
N
L
Q
S
W
V
R
E
Q
H
P
Site 7
S120
V
R
E
Q
H
P
E
S
G
E
E
V
V
V
L
Site 8
T160
C
C
K
M
A
L
L
T
Q
T
Q
G
S
Q
S
Site 9
T162
K
M
A
L
L
T
Q
T
Q
G
S
Q
S
S
Q
Site 10
S165
L
L
T
Q
T
Q
G
S
Q
S
S
Q
C
Q
P
Site 11
S167
T
Q
T
Q
G
S
Q
S
S
Q
C
Q
P
M
K
Site 12
S168
Q
T
Q
G
S
Q
S
S
Q
C
Q
P
M
K
A
Site 13
S181
K
A
L
F
K
H
E
S
L
G
S
Q
P
L
H
Site 14
S184
F
K
H
E
S
L
G
S
Q
P
L
H
D
R
V
Site 15
S217
A
S
R
L
T
P
G
S
Q
G
L
L
K
M
E
Site 16
T229
K
M
E
D
V
A
L
T
L
T
P
G
W
T
Q
Site 17
T231
E
D
V
A
L
T
L
T
P
G
W
T
Q
L
D
Site 18
T235
L
T
L
T
P
G
W
T
Q
L
D
S
S
Q
V
Site 19
S239
P
G
W
T
Q
L
D
S
S
Q
V
N
L
Y
R
Site 20
S240
G
W
T
Q
L
D
S
S
Q
V
N
L
Y
R
D
Site 21
S254
D
E
K
Q
E
N
H
S
S
L
V
S
L
G
G
Site 22
S255
E
K
Q
E
N
H
S
S
L
V
S
L
G
G
E
Site 23
S258
E
N
H
S
S
L
V
S
L
G
G
E
I
Q
T
Site 24
S267
G
G
E
I
Q
T
K
S
R
D
L
P
P
V
K
Site 25
Y321
A
I
G
S
R
R
H
Y
C
H
E
C
G
K
S
Site 26
S328
Y
C
H
E
C
G
K
S
F
A
Q
S
S
G
L
Site 27
S332
C
G
K
S
F
A
Q
S
S
G
L
T
K
H
R
Site 28
S333
G
K
S
F
A
Q
S
S
G
L
T
K
H
R
R
Site 29
T336
F
A
Q
S
S
G
L
T
K
H
R
R
I
H
T
Site 30
T343
T
K
H
R
R
I
H
T
G
E
K
P
Y
E
C
Site 31
T356
E
C
E
D
C
G
K
T
F
I
G
S
S
A
L
Site 32
T371
V
I
H
Q
R
V
H
T
G
E
K
P
Y
E
C
Site 33
Y376
V
H
T
G
E
K
P
Y
E
C
E
E
C
G
K
Site 34
S386
E
E
C
G
K
V
F
S
H
S
S
N
L
I
K
Site 35
S388
C
G
K
V
F
S
H
S
S
N
L
I
K
H
Q
Site 36
S389
G
K
V
F
S
H
S
S
N
L
I
K
H
Q
R
Site 37
T397
N
L
I
K
H
Q
R
T
H
T
G
E
K
P
Y
Site 38
T399
I
K
H
Q
R
T
H
T
G
E
K
P
Y
E
C
Site 39
Y404
T
H
T
G
E
K
P
Y
E
C
D
D
C
G
K
Site 40
T412
E
C
D
D
C
G
K
T
F
S
Q
S
C
S
L
Site 41
S414
D
D
C
G
K
T
F
S
Q
S
C
S
L
L
E
Site 42
S416
C
G
K
T
F
S
Q
S
C
S
L
L
E
H
H
Site 43
S418
K
T
F
S
Q
S
C
S
L
L
E
H
H
K
I
Site 44
T427
L
E
H
H
K
I
H
T
G
E
K
P
Y
Q
C
Site 45
Y432
I
H
T
G
E
K
P
Y
Q
C
N
M
C
G
K
Site 46
S445
G
K
A
F
R
R
N
S
H
L
L
R
H
Q
R
Site 47
S467
Q
N
P
E
H
G
E
S
W
E
S
Q
G
R
T
Site 48
S470
E
H
G
E
S
W
E
S
Q
G
R
T
E
S
Q
Site 49
T474
S
W
E
S
Q
G
R
T
E
S
Q
W
E
N
T
Site 50
S476
E
S
Q
G
R
T
E
S
Q
W
E
N
T
E
A
Site 51
T481
T
E
S
Q
W
E
N
T
E
A
P
V
S
Y
K
Site 52
S495
K
C
N
E
C
E
R
S
F
T
R
N
R
S
L
Site 53
T497
N
E
C
E
R
S
F
T
R
N
R
S
L
I
E
Site 54
S501
R
S
F
T
R
N
R
S
L
I
E
H
Q
K
I
Site 55
T510
I
E
H
Q
K
I
H
T
G
E
K
P
Y
Q
C
Site 56
Y515
I
H
T
G
E
K
P
Y
Q
C
D
T
C
G
K
Site 57
S528
G
K
G
F
T
R
T
S
Y
L
V
Q
H
Q
R
Site 58
Y529
K
G
F
T
R
T
S
Y
L
V
Q
H
Q
R
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation