PhosphoNET

           
Protein Info 
   
Short Name:  UBE2F
Full Name:  NEDD8-conjugating enzyme UBE2F
Alias:  NCE2; NEDD8 conjugating enzyme; ubiquitin-conjugating enzyme E2F
Type:  Ubiquitin ligase; Ligase; EC 6.3.2.-
Mass (Da):  21080
Number AA:  185
UniProt ID:  Q969M7
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:  GO:0005524  GO:0019788  GO:0005515 PhosphoSite+ KinaseNET
Biological Process:  GO:0019941  GO:0045116  GO:0051246 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S17RDDGLKGSRTAATAS
Site 2T19DGLKGSRTAATASDS
Site 3T22KGSRTAATASDSTRR
Site 4S26TAATASDSTRRVSVR
Site 5T27AATASDSTRRVSVRD
Site 6S31SDSTRRVSVRDKLLV
Site 7T68KLHCFQLTVTPDEGY
Site 8T70HCFQLTVTPDEGYYQ
Site 9Y75TVTPDEGYYQGGKFQ
Site 10Y76VTPDEGYYQGGKFQF
Site 11T85GGKFQFETEVPDAYN
Site 12Y91ETEVPDAYNMVPPKV
Site 13S118ETGEICLSLLREHSI
Site 14S124LSLLREHSIDGTGWA
Site 15T128REHSIDGTGWAPTRT
Site 16T135TGWAPTRTLKDVVWG
Site 17Y179FRNKVDDYIKRYAR_
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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