PhosphoNET

           
Protein Info 
   
Short Name:  UBE2E3
Full Name:  Ubiquitin-conjugating enzyme E2 E3
Alias:  UB2E3; UB6C; UBCE4; UbcH9; UbcM2; UBE2E4P; Ubiquitin carrier protein E3; Ubiquitin-conjugating enzyme E2-23 kDa; Ubiquitin-protein ligase E3
Type:  Ubiquitin ligase; EC 6.3.2.19; Ubiquitin conjugating system; Ligase
Mass (Da):  22913
Number AA:  207
UniProt ID:  Q969T4
International Prot ID:  IPI00056504
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005737  GO:0005634   Uniprot OncoNet
Molecular Function:  GO:0005524  GO:0005515  GO:0004842 PhosphoSite+ KinaseNET
Biological Process:  GO:0019941  GO:0043687  GO:0040008 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S8MSSDRQRSDDESPST
Site 2S12RQRSDDESPSTSSGS
Site 3S14RSDDESPSTSSGSSD
Site 4T15SDDESPSTSSGSSDA
Site 5S16DDESPSTSSGSSDAD
Site 6S20PSTSSGSSDADQRDP
Site 7S41EQEERKPSATQQKKN
Site 8T43EERKPSATQQKKNTK
Site 9T55NTKLSSKTTAKLSTS
Site 10T56TKLSSKTTAKLSTSA
Site 11S60SKTTAKLSTSAKRIQ
Site 12S62TTAKLSTSAKRIQKE
Site 13T74QKELAEITLDPPPNC
Site 14S82LDPPPNCSAGPKGDN
Site 15Y91GPKGDNIYEWRSTIL
Site 16S95DNIYEWRSTILGPPG
Site 17T96NIYEWRSTILGPPGS
Site 18S117FFLDITFSSDYPFKP
Site 19S118FLDITFSSDYPFKPP
Site 20Y120DITFSSDYPFKPPKV
Site 21T128PFKPPKVTFRTRIYH
Site 22Y134VTFRTRIYHCNINSQ
Site 23S154DILKDNWSPALTISK
Site 24Y187VGSIATQYLTNRAEH
Site 25T189SIATQYLTNRAEHDR
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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